Which statements are TRUE regarding internal standards?  I. The response factor is calculated by using a mixture containing known amounts of analyte and internal standard and by using detector response to the analyte and the internal standard. II. Internal standards are useful where instrument response or quantity of sample analyzed varies over time. III. Detector response is inversely proportional to concentration. IV. Detector response to analyte and internal standard is assumed to be constant over a range of concentrations A. I, II, and III         B. II, III, and IV         C. I and II       D. I, II, and IV

Fundamentals Of Analytical Chemistry
9th Edition
ISBN:9781285640686
Author:Skoog
Publisher:Skoog
Chapter8: Sampling, Standardization, And Calibration
Section: Chapter Questions
Problem 8.20QAP
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Which statements are TRUE regarding internal standards? 

I. The response factor is calculated by using a mixture containing known amounts of analyte and internal standard and by using detector response to the analyte and the internal standard.

II. Internal standards are useful where instrument response or quantity of sample analyzed varies over time.

III. Detector response is inversely proportional to concentration.

IV. Detector response to analyte and internal standard is assumed to be constant over a range of concentrations

A. I, II, and III         B. II, III, and IV         C. I and II       D. I, II, and IV

 

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