Why do you think antibodies against the N-terminal domain (NTD) provide protection against SARS-CoV2 when the NTD does not interact with the ACE2 receptor?   Question 23 options:   Binding causes steric hindrance of ACE2 to the receptor binding domain (RBD).   Antibodies interact with antigens using a lock-and-key interaction   Antibodies against the NTD recruit antibodies against the receptor binding domain (RBD).   Antibodies against the NTD are not protective.   Binding causes a conformational change in the RBD domain.

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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Why do you think antibodies against the N-terminal domain (NTD) provide protection against SARS-CoV2 when the NTD does not interact with the ACE2 receptor?

 

Question 23 options:

 

Binding causes steric hindrance of ACE2 to the receptor binding domain (RBD).

 

Antibodies interact with antigens using a lock-and-key interaction

 

Antibodies against the NTD recruit antibodies against the receptor binding domain (RBD).

 

Antibodies against the NTD are not protective.

 

Binding causes a conformational change in the RBD domain.

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