Same question but two different sections Why is the Ras small GTPase so dangerous when it is no longer able to hydrolyze GTP to GDP?O A. GTP will build up to toxic concentrations within the cell and trigger necrotic cell death.B. Ras-GTP will persist in the cell and trigger out of control cell proliferation.C. Phosphodiesterase will be inhibited and prevent PKA activation.D. Ras will no longer be able to efficiently bind to its downstream effectors in the crowded cytoplasm. Protein scaffolds are an important part of intracellular signaling following activation of receptors on the cell membrane. This isbecause scaffoldsA. cause conformational changes in G proteinsB. help proteins find each other to transmit signals in the dense cytoplasmC. initiate positive feedback loops to alter protein levels in the cytoplasmD. lead to changes in protein synthesis

Answered: Why is the Ras small GTPase so…

Why is the Ras small GTPase so dangerous when it is no longer able to hydrolyze GTP to GDP? O A CTD will build un to toxie coneentrotione within the ooll ond trigger pooretio ooll deoth

Human Physiology: From Cells to Systems (MindTap Course List)

9th Edition

ISBN:9781285866932

Author:Lauralee Sherwood

Publisher:Lauralee Sherwood

Chapter12: Body Defenses

Section: Chapter Questions

Problem 12RE

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Question

Same question but two different sections

Why is the Ras small GTPase so dangerous when it is no longer able to hydrolyze GTP to GDP?
O A. GTP will build up to toxic concentrations within the cell and trigger necrotic cell death.
B. Ras-GTP will persist in the cell and trigger out of control cell proliferation.
C. Phosphodiesterase will be inhibited and prevent PKA activation.
D. Ras will no longer be able to efficiently bind to its downstream effectors in the crowded cytoplasm.

Protein scaffolds are an important part of intracellular signaling following activation of receptors on the cell membrane. This is
because scaffolds
A. cause conformational changes in G proteins
B. help proteins find each other to transmit signals in the dense cytoplasm
C. initiate positive feedback loops to alter protein levels in the cytoplasm
D. lead to changes in protein synthesis

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RAS protein

RAS proteins are small group of GTPase which main function is to transmit signals within the cells.

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