With regard to the glyceraldehyde-3-phosphate dehydrogenase enzyme reaction: a) Write the mechanism of the reaction. b) What two enzyme intermediates are involved? One undergoes an oxidation-reduction step. What is oxidized and what is reduced? How are the electrons transferred? The second intermediate has some different chemistry than usual esters. Comment. c) What factors are operating here to bring about the catalysis that this enzyme carries out?

Question

With regard to the glyceraldehyde-3-phosphate dehydrogenase enzyme reaction:
a) Write the mechanism of the reaction.
b) What two enzyme intermediates are involved? One undergoes an oxidation-reduction step.
What is oxidized and what is reduced? How are the electrons transferred? The second
intermediate has some different chemistry than usual esters. Comment.
c) What factors are operating here to bring about the catalysis that this enzyme carries out?
d) The product of this reaction is “rather special”. Comment

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