Chapter 11, Problem 24RQ

A patient's medication history lists they are taking Drug C. The drug manual states that C Drug C relies heavily on CYP-450 for metabolism. The nurse best identifies need for a dosage adjustment by contacting the prescriber to:   A) Increase the dose of Drug C if ketoconazole is ordered. B ) Make them aware of potential toxicity if efavirenz is ordered.  C)  Make them aware of potential subtherapeutic drug levels if erythromycin is ordered. D ) Reduce the dose of Drug C if phenytoin is ordered