   Chapter 15, Problem 2CAQ2

Chapter
Section
Textbook Problem

Case 2Using the total oxygen delivery formula ( D O 2 ) (discussed in Chapter 6), calculate and compare the D O when the patient was receiving 5 cm H 2 O PEEP compared with 10 cm H 2 O PEEP.

Summary Introduction

To review:

The DO2, if a patient receiving 5 cm H2O would have received 10 cm H2O.

Introduction:

The partial pressure of oxygen in the sea is about 100 mm Hg while that in a solution is equal to 3 mL O2/L of blood. Oxygen is carried by the blood in two forms, that is, the dissolved form and bound to Hb (hemoglobin).

Please refer to Clinical Application Case-2 for further information.

Explanation

The total oxygen content of arterial blood is denoted by CaO2. It can be calculated by using the following formula:

CaO2(Hb × 1.34 × SaO2) + (PaO2× 0.003)

Putting the values of Hb as 15 g/dL, SaO2 as 91%, and PaO2 as 57% for calculating the CaO2 of Profile 1, we get:

CaO2(15 × 1.34 × 0.91) + (57× 0.003)CaO2(18.29) + (0.17)CaO2= 18.46

Putting the values of Hb as 15 g/dL, SaO2 as 90%, and PaO2 as 61% for calculating the CaO2 of Profile 2, we get:

CaO2(15 × 1.34 × 0.90) + (61× 0.003)CaO2(18.09) + (0.18)CaO2= 18.27

Total oxygen delivery can be calculated by using the following formula:

DO2= QT× CaO2× 10

Putting the values of QT as 3

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