Chapter 17, Problem 19CRQ

Which of the following sentences is correct regarding the pharmacokinetics: a. It deals with the molecular mechanisms of drugs in the body b. It concerns with new drugs synthesis and pharmaceutical formulations  c. It concerns with the therapeutic effects of drugs on the body d. It is the study of drug absorption, distribution and elimination over a course of time

(a)  What is the dosage form of the two above drugs?  (b)  What is the administration method for the two above drugs?   Molnupiravir has not been approved but has been authorized for emergency use by the FDA under an EUA to treat mild to moderate COVID-19 infection. Briefly explain this decision made by FDA based on the knowledge of clinical trials. Both drugs are not allowed to be prescribed to person under 18 years old due to insufficient clinical data. Why is it necessary to separately conduct clinical trials for a younger age group?

During therapy with an intravenous aminoglycoside, the patient calls the nurse and says, “I’m hearing some odd sounds, like ringing, in my ears.” What is the nurse’s priority action at this time?a) Reassure the patient that these are expected adverse effects.b) Reduce the rate of the intravenous infusion.c) Increase the rate of the intravenous infusion.d) Stop the infusion immediately.