Chapter 8, Problem 26RQ

As a pharmacist, propose some improvement that can be implemented to further improve the formulation stability. Please Answer this case study using your own words.

Classification (Chemical and Therapeutic) of the Pexidartinib Trade Names of the Pexidartinib (international and national) and write Generic name/ Chemical name. Mechanism of action and effects of the Pexidartinib with diagrammatic representation Doses, dosage forms, routes of administration, clinical uses and off label use if any of the Pexidartinib Drug-drug or drug-food interactions Contraindications, Precautions and Counselling points of the medication all the Q about Pexidartinib drug

Give an example of N-dealkylation and oxidative deamination over the active molecule of a drug and indicate which type of metabolization they are.

What is meant by the rate-limiting step in drug bioavailability from a solid oral drug product? This under Bipharmaceurics and Pharmacokinetics subject

Routes of drug administration and factors that influence the choice.  Mechanisms of drug movement across biological membranes and factors that influence drug solubility and membrane permeability.  Factors that influence drug bioavailability

How much active ingredient in 20 cc of a 15% solution?     You have 1:1000 concentration of epinephrine. How many mLs do you need to draw up if you want to give 45 mg of the drug?     (I need help please :)

Drug Calculations. Solve all the questions

100. Unwanted but unavoidable pharmacodynamics effects of a drug at the therapeutic dose is known as?• Hypersensitivity• Side effects• Toxic effects• Idiosyncrasy.

Identify the binding interactions that might be possible for the drug reported below. Rank these interactions by increasing energy.