Aldosterone

Primary Adrenal Insufficiency, better known as Addison disease is a chronic endocrine disorder that is only present in only one in 100,000 people. Addison’s disease is seen in two forms called primary and secondary insufficiency. Primary adrenal insufficiency hails from the adrenal glands when specific hormones like mineralocorticoids, glucocorticoids, and androgens stop functioning due to damage from autoimmune diseases, which makes the body attack itself because the immune system is being tricked

Assessment of cortisol concentration saliva as alternative to blood has been validated and several species. Salvia collection is noninvasive and more convenient then blood or urine. Another important point is that the direct measurement of the free biologically active fraction of glucocotrcoid hormones is possible without further laboratory work therefore concentrations are less affected corticosteroid proteins and plasma values. Activation of the HPA access is affected by a variety of factors.

Adrenoleukodystrophy, or ALD, is a deadly genetic disease that affects 1 in 35, 000 people. It most severely affects boys and men. It knows no racial, ethnic, or geographic barriers. ALD is currently not curable, but doctors can help slow progression. Symptoms of ALD include weak muscles, poor appetite, weight loss, paralysis, seizures, developmental delay , mental retardation , and vision and hearing impairment. Treatment methods differ depending on the type of ALD one has. Steroids can be used

RAAS can be good for blood pressure maintenance there are some drawbacks. Angiotensin II can cause structural changes of the heart and blood vessels. It can be implicated hypertrophy and remodeling within the heart. Aldosterone also has adverse effects. Like angiotensin II, aldosterone can cause cardiac remodeling as well as a decreased reuptake of norepinephrine in the heart. This can increase the chances of dysrhythmias (Burchum 472). In a healthy heart these adverse effects would not be seen, but

Aldosterone is the mineralocorticoid steroid which is release from the adrenal gland, situated superior to the kidney. Aldosterone play a major role for the retention of water and sodium in the nephrone (10) in the patient with congestive heart failure, cirrhosis, and nephrotic syndrome (25). The level of the Aldosterone will increase in the patient of heart failure when angiotensin I receptors is activated by Angiotensin II leading to fluid overload (10). Mineralocorticoid/aldosterone receptor

Abstract Addison’s Disease goes unnoticed in a lot of people. Addison’s is sometimes called the uncommon common disease because people are walking around with it but the symptoms are so closely associated with other illnesses, go undetected. Knowledgeable professionals are even hard to find. People knowing living with Addison’s Disease are constantly in fear not knowing if they were to go in a crisis, who would have enough knowledge about the disease to assist. Yes, most first responders, ER staff

Stress is what happens when the body responds to a threat. When the brain feels that the body is being threatened or the brain feels pressure the brain causes the nervous system to release stress hormones and “awakens” or alarms the body to create stress. Stress can also be explained as when you are mentally or emotionally strained or tired from difficult or very demanding tasks. Another way to define stress is when you feel as though something or someone is making you feel like everything is very

Dwight Ingle noticed the relationship between adrenal cortices and cortin; however, administration of adrenotropic principle had shown to prevent deterioration in the adrenal cortex. He then conducted a study on the effects of cortin on adrenal cortices of normal and hypophysectomized rats. This to the hypothesis that cortin is mediated through the anterior lobe of the pituitary, which may regulate the adrenotropic principle activity. He analyzed the data by comparing the combined weights of adrenal

nervous system. According to the website Symptomfind.com, the average amount of potassium in the blood should be between 3.5 to 5.0 mEq/L. (Symptomfind.com, 2017) An increase of the potassium levels stimulates the release of aldosterone from the renin-angiotensin-aldosterone mechanism or by directly releasing it from the adrenal cortex cells In case of a decrease of the potassium level, the amount of secretion and excretion is kept to a minimum level due to the low osmotic pressure of this electrolyte

Renin Angiotensin Aldosterone System (RAAS) is the system that regulates blood pressure in the body. When the body detects low blood pressure (low fluid/low salts), the liver releases angiotensinogen (Bayer pharma, 2015). The release of the angiotensinogen is the beginning of the signal transduction pathway (Bayer pharma, 2015). The angiotensinogen and renin react together to form angiotensin I, then angiotensin-converting enzyme (ACE) converts angiotensin I into angiotensin II (Bayer pharma