Neoplasm

Prolactinoma is usually a benign tumor that appears as a result of the monoclonal expansion of a cell line of adenohypophysis lactotrope cells [1]. Pituitary tumors represent the most common intracranial neoplasms accompanying serious morbidity through mass effects, and inappropriate secretion of pituitary hormones [2]. Prolactin-secreting tumor (prolactinomas) is the most frequently occurring pituitary tumor. Prolactinomas (PRLoman) are thought to have a prevalence of 100/million population [3]

literature. Hepatocellular carcinoma is the most common hepatic malignancy. Extrahepatic metastasis of liver cancers occurs through three routes including hematogenous, lymphogenous, and direct invasion1-3. Direct serosal invasion by contiguous neoplasm was the major mode of GI tract involvement with unusual clinical presentations. The presumed mode of direct involvement of the GI tract is initiated by the adhesion of the serosal side of the adjacent organ with a bulky, exophytic tumor. Direct invasion

inter-variability among neuropathologist experts. More importantly, 2007 WHO grading doesn’t contemplate the continuum between grade II and III. In fact, many DLGG has an “intermediate” behavior, with some more aggressive microfoci lodged in the core of the neoplasm (19,23,24). Hence, the term diffuse low-grade glioma is preferred in this article. In fact, DLGG is slower

Tumors are abnormal mass of tissue that is filled with fluid or is solid and are also called neoplasm. Tumors has three different stages-benign, pre-malignant and malignant. Benign is a tumor that is not cancerous, pre-malignant is a pre-cancerous tumor, and malignant is a cancerous tumor. Three types of tumors I am going to discuss are glioma, lipoma, and fibroma. These three tumors are classified as benign tumors. Glioma is a tumor that occurs in the brain and different parts of the nervous system

Cancer is a systemic disease and advanced cancers can be locally advanced or metastatic. Generally, the metastatic potential is through to be due to tumor heterogeneities which origin from the differences generated in the evolution process of cancer itself as well as host microenvironment. The capability of invasion and metastasis is closely related to cell motility and requires the cytoskeleton that is essential during mitoses[18]. Since malignancy criteria are mainly related to the phenotype of

Methotrexate is an antimetabolite of folic acid that blocks the formation of thymine within the cell, rendering it incapable of DNA replication. As a chemotherapeutic agent, it is also employed as an alternative treatment for psoriasis and rheumatoid arthritis when they are unresponsive to conventional therapies. Methotrexate (MTX) induces an effect similar to 5-fluorouracil (5-FU) by interrupting the formation of thymine within the cell, which leads to the inability to replicate DNA. Unlike 5-FU

Sweat gland neoplasms are extremely rare neoplasms. They can be classified into benign and malignant variety. The benign variety have been sub divided into subtypes such as nodular, apocrine and clear cell based on their histo-pathological presentation. The malignant form or sweat gland carcinomas are those that possess an infiltrative and/or metastatic potential. They are generally classified into two groups. The first group comprises malignant tumours that closely mimic their benign counterparts

trillion US dollars per year as of 2010. The development of mathematical models of tumor cells is important to the growth kinetics, which may lead to the development of successful treatment strategies. Because of the great variance in malignant neoplasms (the cause of cancer), research has not been great enough to save the

Biotechnological solutions to a variety of illnesses, surgical procedures, genetic exploits and a myriad of other things are now in the form of nanotechnology. Big pharmaceutical companies now refer to many of their medications, in fact, as nanomedicines, which alludes to the nanotechnological inputs in pills that improve delivery methods and even deploy nanoparticles for specific purposes on occasion. A new study actually illustrates how attaching RNA nanoparticles that masquerade as antibodies

Pediatric low-grade gliomas (pLGG) are the most common pediatric brain tumor and account for 35% of central nervous system tumors in children (1–4). pLGG includes a range of histologic types with WHO grade I pilocytic astrocytoma being the most frequent (3). Clinically, pLGGs are generally slow growing lesions that can occur throughout the central nervous system and are surgically removedwhen possible.Complete surgical resection is the most significant predictor of improved survival in pLGG (5)