Neoplasm

As immuno-oncology takes the spotlight in cancer therapeutics and pharma companies race to develop new treatments, improvements in the detection of cancers may be just as impactful. Liquid biopsies, top ten technology MIT Technology Review 2015 breakthroughs, are diagnostic tests to detect cancer biomarkers in the blood, urine, and now saliva. Liquid biopsies have been recent blood based tests that analyze circulating tumor DNA (ctDNA) or circulating tumor cells (CTCs) in lieu of the standard tissue

Dr. Tullio Simoncini conducted research on Candida and cancer and found that 79 to 97 percent of all cancer patients also have Candida infection. Now here’s the “rationale” behind this whole dubious idea: Dr. Simoncini’s explanation how Candida is linked to cancer: 1.Candida roots itself in your deep connective tissue in various organs. 2.As a result, this evokes an organic defensive reaction as the connective tissue of your invaded organ attempts to encyst the fungin colonies through cellular

Lymphoma comes in two types Hodgkin’s and non-Hodgkin's Both types are a cancer based disease of the cells. The body constantly makes new cells to help us grow, replace worn-out tissue and heal injuries.Cancer occurs when the cells don't grow, divide and die in the usual way. This then causes blood of lymph fluid in the body to become abnormal, or form a lump called a tumour. These types of tumors are the Benign tumor which the cells are confined into one area and are not able to spread to other

Choroidal melanoma is the most common intraocular (inside the eye) tumor in adults. Choroidal melanoma is the most common cancer of the eye. It originates from the pigmented cells of the choroid of the eye, it is not like other tumors that starts in other parts of the body and then spreads to the eye. Choroidal melanoma is malignant; it can metastasize and eventually spread to other parts of the body. In COMS (The Collaborative Ocular Melanoma Study) states that choroidal melanoma initially appearing

Brain tumor Clinical feature A brain tumor is an abnormal development of tissue in the brain or central spine, which is accountable for appropriate brain functionality. Brain and spinal cord tumors are atypical growths of tissue found inside the skull or the bony spinal column, which are the chief constituents of the central nervous system (CNS). Benign tumors are noncancerous and malignant tumors are cancerous. The central nervous system (CNS) is accommodated within rigid, bony quarters (i.e., the

The echinococcus granulosus has been described as the most frequent cause of the hydatid cysts. Humans are the incidental intermediate host. Larvae emerge from the eggs in the intestine; and after invasion to the blood vessels, they can migrate into almost every part of the body.The usual destination is the liver via the portal tract, but sometimes the larvae pass through the liver barrier and reach the lungs and all the other viscera, where they transform into small cysts.The cyst of echinococcus

The average tumor size on imaging was 10.2x10.4 cm and ranged from 5x6cm to 16x13cm. Older children had comparatively larger tumor sizes. In malignant GCTs, no significant reduction in the average tumor size was noticed post neoadjuvant chemotherapy. On gross examination the tumors were heterogenous, lobulated with cystic and solid areas and occasional calcification. Histology revealed 9 (75%) as mature teratomas and 3 (25%) as immature teratomas. The immature teratomas presented with raised αFP

Therefore, a cancer that involves a mutation in these BRAC1 and BRAC2 genes (BRCAness) can be effectively treated with PARP1 inhibitors, which may represent very efficient therapies for TNBC because of the high sensitivity of these tumours to the inhibitor and moreimportantly, it is devoid of harmful effects on the remaining healthy cells. This contrasts with conventional chemotherapies, which are highly toxic to all cells and can provoke DNA damage in healthy cells that may further lead to secondary

WEfforts over the past decade to characterize the genetic alterations in human cancers have led to a better understanding of molecular drivers of this complex set of diseases. Although we in the cancer field hoped that this would lead to more effective drugs, historically, our ability to translate cancer research to clinical success has been remarkably low1. Sadly, clinical trials in oncology have the highest failure rate compared with other therapeutic areas. Given the high unmet need in oncology

Stereotactic radiosurgery works the same as all other forms of radiation treatment. It does not remove the tumor or lesion, but is distorts the DNA of the tumor cells. The cells then lose their ability to reproduce and retain fluids. The tumor reduction occurs at the rate of normal growth for the specific tumor cell. In lesions such as AVMs (a tangle of blood vessels in the brain), radiosurgery causes the blood vessels to thicken and close off. The shrinking of a tumor or closing off of a vessel