Progesterone

applicator is inserted into the vagina daily or as directed by the doctor, starting a day after ovulation or between the 18th day to 20th day of menstrual cycle. If pregnancy occurs, continue using the gel until the placenta is producing adequate progesterone to maintain the pregnancy; Crinone 8 gel is used for at least the first 12 weeks after conception. Some women find it uncomfortable inserting the medication in the vagina, however, if the doctor has prescribed the drug it is important to use

Since the standard enzyme immunoassay identification of progesterone (EIA) is currently performed and standardized using microtitre plates.This technique was a starting point and need Ab raised against other innocent animals. Therefore there is an urgent need for development of artificial and low cost recognition sites for progesterone detection. Progesterone is known as a “hormone of pregnancy”. As in cyclic non-pregnant animal, the progesterone level in plasma and milk decreases during follicular

A secondary corpus luteum develops Progesterone is the most important hormone as after ovulation – (during the luteal phase) progesterone levels will increase slowly. This will suppress the GnRH release which in turn will diminish the release of LH and FSH (these hormones are not required at this stage of the cycle). Having reached its optimum level Oestrogen will now slowly decline. The main effect of progesterone is that it stimulates endometrium growth if an egg is implanted

In the current breeding practices, management of the estrous cycle is a common. Breeders want to know when their mare is in one phase or the other and also wants to be able to determine when she will ovulate. Manipulation of the estrous cycle is a practice of breeding management. Manipulation of estrous involves changing the normal cycle through hormone treatments or other methods. Managing and manipulating the estrous cycle allows breeders to have control over the phase the mare is experiencing

the preoptic and arcuate nucleus of the hypothalamus. The hormone is released into the hypophyseal portal system, and stimulates the pituitary follicles, which encourages hormone secretion. This in turn encourages the secretion of estradiol and progesterone by the ovaries. The hypothalamus-pituitary-adrenal axis (HPA) is part of the stress response system, and has the effect of changing the organism's behavior in order to increase the organism's chances to survive the stressful situation. When stress

2.10. MTT Assay 3-[4,5-dimethylthiazol-2-yl]2,5-diphenyltetrazolium bromide (MTT) is a yellow water soluble tetrazolium salt. A mitochondrial enzyme in living cells, succinate-dehydrogenase, cleaves the tetrazolium ring, converting the MTT to an insoluble purple formazan. Therefore, the amount of formazan produced is directly proportional to the number of viable cells. After 48 h of incubation, 15
L of MTT (5 mg/mL) in phosphate buffered saline (PBS) was added to each well and incubated at 37˚C

for a female animal. The estrous cycle has four stages: proestrus, estrus, metestrus, and diestrus. Proestrus is the first stage, and lasts approximately three days. During this stage of estrus, follicle growth begins due to the decrease in progesterone and increase in follicle stimulating hormone and estrogen. The corpus luteum is disintegrated, and the endometrium (the uterine lining) begins developing. After proestrus, is estrus, which lasts approximately twelve to eighteen hours. Estrus

Researchers have found evidence of estrogen, progesterone, and testosterone receptors are found within human ACLs (Slauterbeck, Hardy, 196). An increase in the levels of estrogen in ACL tissue cultures found a decrease in fibrobasts and procollagen production (Slauterbeck, Hardy, 197). The results that were found suggest that the variation in steroid hormone levels during the menstrual cycle and its effects on MMPs and TIMPs genes that are found in the ACL (Slauterbeck, Hardy, 197). The MMPs found

and progesterone are hormones generated by the ovaries. These hormones have a variety of fundamental uses in the body of a female. Estrogen initiates thickening of the uterus wall in preparation for implantation of a fertilized ovum. Also, estrogen plays a role in the metabolism of calcium in the body. Apart from these two roles, estrogen also participates in the maintenance of cholesterol levels within the normal limits. Estrogen is also implicated in keeping the vagina healthy. Progesterone, on

In other words we can say that progesterone is a vital hormone to continue a pregnancy. Mifeprex composed of a synthetic steroidal derivative i.e. Mifepristone, which belongs to the category of Oxosteroids. It is an agonist of progesterone receptors, which performs anti-progesterone activity. It has a strong tendency to bind with progesterone receptors, which results in the prevention of the functioning of the endogenous or exogenous progesterone. This activity is useful to detach the fetus