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  • Comparison Of Thymus With Unhealthy Spleen

    1013 Words  | 5 Pages

    Introduction Purpose of this practical is to compare tissues in healthy spleen and thymus with unhealthy spleen and thymus of a mouse. Lymphoid organs consist of primary (thymus, bone marrow) and secondary (spleen, tonsils, lymphoid nodule in the intestine, and appendix) organs. In contrast, the primary organs do not depend on antigens such as thymus, and the secondary organs like spleen depend on antigens. Spleen Spleen is a small organ located behind the stomach in the left upper part of the

  • What Is Myasthenia Gravis?

    1096 Words  | 5 Pages

    important common neuromuscular disorders. Although it is categorized as a neuromuscular disease , there are few other factors other than acquired immunological abnormality , like genetic abnormality in neuromuscular junction , and some relations to thymus diseases and cancers. Myasthenia gravis presents clinically in a variety of ways, with varied symptoms that make it difficult to diagnose it in initial stages. As MG became the subject of interest to neurologists mostly in the past years , however

  • Deletion Syndrome Essay

    717 Words  | 3 Pages

    DiGeorge Syndrome 1 . What are the cellular/molecular mechanisms that underlie this disease? At a molecular level, it is a disease resulting from a sequence microdeletion on chromosome 22.1,4 Its current preferred name is 22q11.2 deletion syndrome.2 It is characterized as loss of about 30-40 genes, with some individuals having shorter deletions in the same region.1 One gene loss TBX1, attributes to heart defects, cleft palate, the distinctive facial feature of the disease, hearing loss and low

  • Cancer Kryptonite: Using Deadly Disease To Cure Deadly

    1879 Words  | 8 Pages

    Cancer Kryptonite: Using Deadly Disease to Cure Deadly Disease After reviewing the study of the effects of chimeric antigen receptor-modified T cells (CAR T-cells) on acute lymphocytic leukemia, it appears that this type of treatment shows promise for the treatment of this and many other difficult-to-kill cancers. This technique was pioneered and developed by Dr. Carl June. He began his research on T cells in the late 1980s to early 1990s while in the Navy. The research he would do and the other

  • Knocking Out Interleukin 2 : Developing Ulcerative Colitis

    2489 Words  | 10 Pages

    TITLE Knocking-out Interleukin-2: Developing Ulcerative Colitis, or a Way to Prevent it? INTRODUCTION It is of great interest to see how far the scientific community has come across with identifying the genes and functions of each encoding protein. The science brought different interventions, as each gene has the possibility of interaction and the whole cellular environment has a type of role to engage in the complex day to day regulation of our eukaryotic cells. It is very interesting to also

  • The Battle Between Cell in the Body and Pathogens in the Enviornment

    643 Words  | 3 Pages

    investigated and the development of T cells and B cells will be compared and contrasted. T and B cells both begin development in the bone marrow as haematopoietic stem cells(Liu et al., 2013). The cells that will become T cells then migrate to the thymus where they mature and the B cells stay in the bone marrow to mature. The function of each cell type is similar in that they both need to protect the body against pathogens; however the mechanisms that they do this differ. T cells bind to antigens

  • Dna Analysis : Dna Fragmentation Essay

    2433 Words  | 10 Pages

    DNA ladder assays were used to evaluate the DNA fragmentation triggered through apoptosis when thymocytes were exposed to various concentration of diethylstilbestrol (DES). There are numerous methods for the quantification of DNA fragmentation but for this study, a lysis and DMSO protocol were used for the detection of apoptosis. Apoptotic DNA fragmentation was analyzed using 2% agarose gels to reveal a ladder-like pattern within each sample. The present study demonstrates a comparison between two

  • Compare and contrast T-cell development with B-cell development

    878 Words  | 4 Pages

    killer T-cells, intraepithelial lymphocytes and regulatory T-cells. Also, the cells are yet to express CD4+ or CD8+ and only express c-kit (CD117) and CD25 on their cell membrane. DN2 is a vital phase, it occurs in the subcapsular cortex of the thymus. It is here that the “genes for the gamma, delta and beta T-cell receptor (TCR) chains” [3] start their rearrangement process. The alpha chain does not commence its rearrangement, as the recombinase machinery cannot reach its gene. In this phase,

  • Wound Healing Essay

    1286 Words  | 6 Pages

    Rosenthal, 2014). Additionally, research has demonstrated that during wound healing, changes occur in the thymus (the organ in which T-cell maturation occurs) revealing increases in thymus size, changes in morphology, and proliferation of a variety of immune cells within the medulla (Franchini & Bertolotti 2014). Research Goals We propose to study the relationship between the thymus, T-cells, and wound healing by performing larval thymectomy to generate T-cell-deficient tadpoles and frogs.

  • The Immune System: The Immune System

    833 Words  | 4 Pages

     "Immune System" Homework                                                                                                                                                                                                                                  The Thymus         At this very moment, an army is attacking you. You are fighting this war without lifting a finger. You are asleep. Eating. Talking. Breathing. Anything you do, you are fighting an army. It's called Influenza. Or pneumonia. Maybe it's bronchitis