Micro Research

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West Coast University *

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290

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Biology

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Feb 20, 2024

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1 Microbial Journal Article Review West Coast University - Miami MICR 290: Microbiology Professor Pedro Perez Diaz 5/22/22
2 Microbial Journal Article Review Question 1: Why did the scientists perform the study (i.e., description of background)? This review was conducted on the journal article, Pasteurized Akkermansia muciniphila increases whole-body energy expenditure and fecal energy excretion in diet-induced obese mice, published by the journal Gut Microbes Volume 11 Issue 5. The scientists conducted this study because the microbe Akkermansia muciniphila is proving to have helpful effects on the metabolism, and discoveries have been made suggesting that this bacterium is a next generation beneficial microbe (Depommier et al., 2020, para. 4). As reported by Pitras (2021, paras. 3–4), anaerobic gram-negative Akkermansia muciniphila is a microbiota of the intestines colonized in the mucus layer of intestinal epithelial cells degrading mucus enzymes as its source of nutrients. Question 2: What was the hypothesis (or hypotheses) under investigation? The hypotheses of this study was that pasteurized Akkermansia muciniphila given daily would reduce diet induced obesity and would influence the use of energy and physical activity (Depommier et al., 2020, para. 5). The scientist noted that other studies have been done showing how having a large amount of Akkermansia muciniphila in the system shows a positive effect but no studies showed how pasteurized Akkermansia muciniphila can effect whole body metabolism and they wanted to prove the effects (Depommier et al., 2020, para. 5). Question 3: What were the major results and did they support or negate the hypothesis? Which key techniques were used to achieve these results? The researched conducted by Depommier et al. (2020, para.17), confirmed their body weight and fat, and increased physical activity. They also found through the feces a high
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