LS7B _ W23 Midterm 1 (pdf) - Course Sidekick
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University of California, Los Angeles *
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LS7B
Subject
Biology
Date
Feb 20, 2024
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30
Uploaded by MagistrateFrogMaster960
3/20/23, 10:20 AM
Midterm I: 23W-LIFESCI-7B-LEC-1 Genetics, Evolution, and Ecology
This quiz has been regraded; your new score reflects 2 questions that were affected. Midterm I Due
Feb 3 at 11:59pm
Points
96
Questions
32 Available
Feb 3 at 6am - Mar 17 at 11:59pm
Time Limit
120 Minutes Instructions This quiz was locked Mar 17 at 11:59pm. Attempt History Attempt
Time
Score
Regraded LATEST
Attempt 1
120 minutes
72 out of 96
78 out of 96 Please READ this entirely before beginning your exam: The exam is available from 6AM PST to 11:59PM PST on Friday, Feb 3
. Once you begin the exam, you have 120 minutes (2 hours) to complete it. Once you start the exam, you must complete the exam. Any exam that is still open at 11:59PM PST, or open for longer than 120 minutes, will be automatically submitted. If you start the exam later than 9:59PM PST, then you will not have the full 120 minutes. The individual phase of the midterm has 32 questions, each worth three points. For multiple True/False questions, each question is independent of the other questions. The exam is open book and open note (you may use Achieve, Bruinlearn, and
your own
notes), but you may not use other internet sites or work with other students during the exam. Your performance on the exam is meant to evaluate your individual effort. You are not allowed to take screenshots for any reason, post questions to third party sites (e.g. Chegg), share any version of the exam you have with other students, or collaborate on this exam in any way. Any of these will be considered an act of academic misconduct and will be reported to the Dean of Students with no exceptions. Please email your instructor immediately if you experience any technical difficulties during the exam. rd
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Score for this quiz:
78
out of 96 Submitted Feb 3 at 11:50am This attempt took 120 minutes. 3/20/23, 10:20 AM
Midterm I: 23W-LIFESCI-7B-LEC-1 Genetics, Evolution, and Ecology [Questions 1-4] Imagine an autosomal co-dominant trait with three different alleles: D, E, and F. For each of the following families, identify the possible nondisjunction events (rare mistakes during meiosis) that could explain the genotype of the offspring. Assume no recombination occurs. 3 / 3 pts Question 1 The XX Parent has genotype EE and the XY Parent has genotype EF. They have a triploid XY offspring that has genotype EEF. This could have occurred through non-disjunction in meiosis II of the XY parent. True False Correct! Correct! Distinguish between sister chromatids and homologous chromosomes Visualize how meiosis produces four haploid gametes Week 1 handout and clicker questions Week 3 clicker questions 3 / 3 pts Question 2
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The XX Parent has genotype DF and the XY Parent has genotype EF. They have a triploid XX offspring that has genotype DFF. This could have occurred through non-disjunction in meiosis II of the XY parent. 3/20/23, 10:20 AM
Midterm I: 23W-LIFESCI-7B-LEC-1 Genetics, Evolution, and Ecology True Correct! Correct! False Distinguish between sister chromatids and homologous chromosomes Visualize how meiosis produces four haploid gametes Week 1 handout and clicker questions Week 3 clicker questions 3 / 3 pts Question 3 The XX Parent has genotype DF and the XY Parent has genotype EF. They have a triploid XY offspring that has genotype DEF. This could have occurred through non-disjunction in meiosis I of the XX Parent. True Correct! Correct! False Distinguish between sister chromatids and homologous chromosomes Visualize how meiosis produces four haploid gametes Week 1 handout and clicker questions Week 3 clicker questions
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3 / 3 pts Question 4 3/20/23, 10:20 AM
Midterm I: 23W-LIFESCI-7B-LEC-1 Genetics, Evolution, and Ecology The XX Parent has genotype DF and XY Parent has genotype DE. They have a triploid XX offspring that has genotype DEF. This could have occurred through non-disjunction in meiosis I of the XY Parent. True Correct! Correct! False Distinguish between sister chromatids and homologous chromosomes Visualize how meiosis produces four haploid gametes Week 1 handout and clicker questions Week 3 clicker questions [Questions 5 - 7] You are a genetic counselor and are meeting with a couple, one of which is affected by Familial glucose-galactose malabsorption (a rare recessive autosomal disorder). They are planning on starting a family and are interested in knowing the probability that their children may or may not have Familial glucose-galactose malabsorption. 3 / 3 pts Question 5
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If the XY parent is affected and they have two children, one XX and one XY offspring, the probability the XY offspring is affected is twice the probability that the XX offspring will be affected. True 3/20/23, 10:20 AM
Midterm I: 23W-LIFESCI-7B-LEC-1 Genetics, Evolution, and Ecology False Correct! Correct! Calculate the probability of a particular gamete being produced from an individual, assuming independent segregation of alleles Use pedigree analysis to calculate the likelihood an individual will have a particular genotype or phenotype Use the multiplication and sum rule Weeks 1 and 2 clicker questions Lab Weeks 3 and 4 3 / 3 pts Question 6 Assume the XY parent is affected, and the XX parent is a carrier. If they have two children, what is the probability that both children will be unaffected? 12/16 9/16 3/16 1 7/16
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None of the other answer choices are correct Correct! Correct! 3/20/23, 10:20 AM
Midterm I: 23W-LIFESCI-7B-LEC-1 Genetics, Evolution, and Ecology Calculate the probability of a particular gamete being produced from an individual, assuming independent segregation of alleles Use pedigree analysis to calculate the likelihood an individual will have a particular genotype or phenotype Use the multiplication and sum rule Weeks 1 and 2 clicker questions Lab Weeks 3 and 4 Original Score: 0 / 3 pts
Regraded Score: 3 / 3 pts Pregunta 7 ± This question has been regraded. Assume the XY parent is affected, and the XX parent is a carrier. If they have two children, what is the probability that both children will have the same genotype? 1/4 1/2 Correct! Correct! 9/16 3/16 None of the other answer choices are correct
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3/20/23, 10:20 AM
Midterm I: 23W-LIFESCI-7B-LEC-1 Genetics, Evolution, and Ecology Calculate the probability of a particular gamete being produced from an individual, assuming independent segregation of alleles Use pedigree analysis to calculate the likelihood an individual will have a particular genotype or phenotype Use the multiplication and sum rule Weeks 1 and 2 clicker questions Lab Weeks 3 and 4 [Questions 8-11] Sadie (an XX individual) and Peder (an XY individual) are concerned about the inheritance of a very rare condition "
A
"
in their family. Sadie's mother, Peder's mother, and Peder are all affected. Both Sadie's and Peder's maternal grandfathers are also affected. Sadie and Peder currently have four offspring two XY offspring that are unaffected and two XX offspring that are affected. No one else in either family has the condition. 0 / 3 pts Question 8 Condition "
A
"
is most-likely an X-linked recessive trait. True ou Answered ou Answered
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False orrect Answer orrect Answer 3/20/23, 10:20 AM
Midterm I: 23W-LIFESCI-7B-LEC-1 Genetics, Evolution, and Ecology Distinguish between dominant, recessive, autosomal,
X
-linked patterns of inheritance using pedigrees Create a pedigree from a scenario Clicker questions Weeks 2 and 3 Lab Week 3 3 / 3 pts Question 9 Based on their family history, what is the probability Sadie and Peder's fifth and sixth child will be affected for Condition "A" 1/36 1/4 Correct! Correct! 1/32 3/16 4/18 1/16 3/32 None of the other answer choices are correct 3/8
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3/20/23, 10:20 AM
Midterm I: 23W-LIFESCI-7B-LEC-1 Genetics, Evolution, and Ecology Distinguish between dominant, recessive, autosomal,
X-linked patterns of inheritance using pedigrees Create a pedigree from a scenario Clicker questions Weeks 2 and 3 Lab Week 3 3 / 3 pts Question 10 The couple is also concerned about color-blindness, another rare disease, which is X-linked. To Sadie and Peder's knowledge all the same individuals with Condition "A", are also color-blind. They do not know if individuals without condition "A" might also be color-blind. The probability that Sadie and Peder's fifth child is a color-blind XX individual is 1. True False Correct! Correct! Distinguish between dominant, recessive, autosomal,
X-linked patterns of inheritance using pedigrees Create a pedigree from a scenario Clicker questions Weeks 2 and 3 Lab Week 3
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0 / 3 pts Question 11 The couple is also concerned about color-blindness, another rare disease, which is X-linked. To Sadie and Peder's knowledge all the same 3/20/23, 10:20 AM
Midterm I: 23W-LIFESCI-7B-LEC-1 Genetics, Evolution, and Ecology individuals with Condition "
A
"
, are also color-blind. They do not know if individuals without condition "
A
"
might also be color-blind. The probability that Sadie and Peder's fifth and sixth child will be sons, and each affected by only one of the diseases is 1/16. True orrect Answer orrect Answer False ou Answered ou Answered Distinguish between dominant, recessive, autosomal,
X-linked patterns of inheritance using pedigrees Create a pedigree from a scenario Clicker questions Weeks 2 and 3 Lab Week 3 [Question 12-15] Scientists identified three colors in reedfish. Fish with a dominant allele (B) of gene B will produce a black pigment, and an individual with homozygous genotype for the recessive allele b will produce a brown pigment. However, gene A also affects the color of a fish. Individuals with a dominant allele (A allele) of gene A will synthesize a protease which destroys both black and brown pigments; therefore, these fish with A allele will be albino. For a fish to have either black or brown colors, it must be homozygous for recessive allele a. A true-breeding brown fish mated with a true-breeding albino fish. All F1 progeny were albino. When these F1 were allowed to cross with each other, they produced an F2 generation which included all three colors:
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black, brown, and albino. 0 / 3 pts Question 12 3/20/23, 10:20 AM
Midterm I: 23W-LIFESCI-7B-LEC-1 Genetics, Evolution, and Ecology The genotype of albino parent is: More than one of the answer choices are correct ou Answered ou Answered AABB orrect Answer orrect Answer AABb AAbb None of the other answer choices are correct AaBb Calculate the probability of a particular gamete being produced from an individual, assuming independent segregation of alleles Interpret the results of crosses and pedigrees whose results differ from Mendelian expectations because of incomplete dominance, epistasis, or hierarchy of dominance Week 2 clicker questions Week 4 lab 3 / 3 pts Question 13
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If the phenotype of one parent is black and the other's is brown, none of their offspring will be albino. True Correct! Correct! False 3/20/23, 10:20 AM
Midterm I: 23W-LIFESCI-7B-LEC-1 Genetics, Evolution, and Ecology Calculate the probability of a particular gamete being produced from an individual, assuming independent segregation of alleles Interpret the results of crosses and pedigrees whose results differ from Mendelian expectations because of incomplete dominance, epistasis, or hierarchy of dominance Week 2 clicker questions Week 4 lab 3 / 3 pts Question 14 Half of the F2 black would be heterozygous. True False Correct! Correct! Calculate the probability of a particular gamete being produced from an individual, assuming independent segregation of alleles Interpret the results of crosses and pedigrees whose results differ from Mendelian expectations because of incomplete dominance, epistasis, or hierarchy of dominance
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Week 2 clicker questions Week 4 lab 3/20/23, 10:20 AM
Midterm I: 23W-LIFESCI-7B-LEC-1 Genetics, Evolution, and Ecology 3 / 3 pts Question 15 If two black parents have some brown among their offspring, both parents must be heterozygous at one locus and homozygous at the other locus. True Correct! Correct! False Calculate the probability of a particular gamete being produced from an individual, assuming independent segregation of alleles Interpret the results of crosses and pedigrees whose results differ from Mendelian expectations because of incomplete dominance, epistasis, or hierarchy of dominance Week 2 clicker questions Week 4 lab 3 / 3 pts Question 16 [Question 16] The following two genotypes are crossed AaBbCcddEe X AabbCcDdEe. Which of the following genotypes will occur in the greatest proportion? (assume independent assortment of all loci) A bbC ddE
Correct!
Correct!
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AabbCcddEe Correct! Correct! AaBbCcDdee AABBCcddEE aabbccddee AabbCcddee 3/20/23, 10:20 AM
Midterm I: 23W-LIFESCI-7B-LEC-1 Genetics, Evolution, and Ecology Calculate the probability of a particular gamete being produced from an individual, assuming independent segregation of alleles [Questions 17 and 18] There is a native species of salamander in California where one phenotype has spots on their sides and the other phenotype does not have spots on their side (they are solid in color). The table shows parental crosses that were done and the phenotypes of the offspring from each cross. 3 / 3 pts Question 17 At least one parent in each cross is heterozygous. True False Correct! Correct!
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3/20/23, 10:20 AM
Midterm I: 23W-LIFESCI-7B-LEC-1 Genetics, Evolution, and Ecology Use pedigree analysis to calculate the likelihood an individual will have a particular genotype or phenotype Distinguish between dominant, recessive, autosomal,
X
-linked patterns of inheritance using pedigrees Clicker questions Weeks 1 and 2 Lab Week 3 3 / 3 pts Question 18 All of the offspring from Cross #2 are heterozygous. True Correct! Correct! False Use pedigree analysis to calculate the likelihood an individual will have a particular genotype or phenotype Distinguish between dominant, recessive, autosomal,
X
-linked patterns of inheritance using pedigrees Clicker questions Weeks 1 and 2 Lab Week 3
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[Questions 19-23] There is a species of treeshrew, which lives in a tropical forest in Indonesia. The fur color of its beautiful tail is determined by
a single autosomal
gene
with
three alleles
that exhibit an unknown hierarchy of dominance. Genetic testing shows that individuals I-1, I-4, III- 4, and III-5 are each homozygous. Use this information and the phenotypes in the pedigree to answer the following questions. 3/20/23, 10:20 AM
Midterm I: 23W-LIFESCI-7B-LEC-1 Genetics, Evolution, and Ecology 3 / 3 pts Question 19 Lucent is dominant over white. True Correct! Correct! False Interpret the results of crosses and pedigrees whose results differ from Mendelian expectations because of incomplete dominance,
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from Mendelian expectations because of incomplete dominance, epistasis, or hierarchy of dominance Use pedigree analysis to calculate the likelihood an individual will have a particular genotype or phenotype Week 2 clicker questions 3/20/23, 10:20 AM
Midterm I: 23W-LIFESCI-7B-LEC-1 Genetics, Evolution, and Ecology 3 / 3 pts Question 20 All white individuals are homozygous. True Correct! Correct! False Interpret the results of crosses and pedigrees whose results differ from Mendelian expectations because of incomplete dominance, epistasis, or hierarchy of dominance Use pedigree analysis to calculate the likelihood an individual will have a particular genotype or phenotype Week 2 clicker questions 0 / 3 pts Question 21 The probability that III-3 is homozygous is: 0 Unable to determine 1/3 orrect Answer orrect Answer
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1/2 1/4 ou Answered ou Answered 3/20/23, 10:20 AM
Midterm I: 23W-LIFESCI-7B-LEC-1 Genetics, Evolution, and Ecology Interpret the results of crosses and pedigrees whose results differ from Mendelian expectations because of incomplete dominance, epistasis, or hierarchy of dominance Use pedigree analysis to calculate the likelihood an individual will have a particular genotype or phenotype Week 2 clicker questions 3 / 3 pts Question 22 The probability that IV-3 and IV-4 have a white offspring is: 1/2 0 1/8 Correct! Correct! 1/4 1 Interpret the results of crosses and pedigrees whose results differ from Mendelian expectations because of incomplete dominance,
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epistasis, or hierarchy of dominance Use pedigree analysis to calculate the likelihood an individual will have a particular genotype or phenotype Week 2 clicker questions 3 / 3 pts Question 23 3/20/23, 10:20 AM
Midterm I: 23W-LIFESCI-7B-LEC-1 Genetics, Evolution, and Ecology Some black individuals are heterozygous. True False Correct! Correct! Interpret the results of crosses and pedigrees whose results differ from Mendelian expectations because of incomplete dominance, epistasis, or hierarchy of dominance Use pedigree analysis to calculate the likelihood an individual will have a particular genotype or phenotype Week 2 clicker questions Original Score: 0 / 3 pts
Regraded Score: 3 / 3 pts Question 24 ± This question has been regraded. [Question 24] In a species of beetles, the allele for a shiny shell (
C
) is dominant to the allele for a dull shell (
c
), and the allele for horns (
P
) is dominant to the allele for a lack of horns (
p
). Consider a cross between CcPp
and
Ccpp
. What proportion of offspring do you expect to have the same genotype as either one of the parents?
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3/16 1/4 3/4 1/2 Correct! Correct! 3/8 3/20/23, 10:20 AM
Midterm I: 23W-LIFESCI-7B-LEC-1 Genetics, Evolution, and Ecology Calculate the probability of a particular gamete being produced from an individual, assuming independent segregation of alleles Week 2 clicker questions [Questions 25-26] Recall that ABO blood groups exhibit a co-dominant pattern of inheritance: I
and I
are codominant and i is recessive to both I
and I
. A human pedigree and the ABO blood types of some of the members of the family are shown in the figure. A
B
A
B
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3 / 3 pts Question 25 Individual II-4 could be blood type B. 3/20/23, 10:20 AM
Midterm I: 23W-LIFESCI-7B-LEC-1 Genetics, Evolution, and Ecology True False Correct! Correct! Interpret the results of crosses and pedigrees whose results differ from Mendelian expectations because of incomplete dominance, epistasis, or hierarchy of dominance Use pedigree analysis to calculate the likelihood an individual will have a particular genotype or phenotype Week 2 clicker questions 3 / 3 pts Question 26 Individual IV-1 has an equal probability of being blood type AB or blood type A. True Correct! Correct! False h
l
f
d
di
h
l
diff
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Interpret the results of crosses and pedigrees whose results differ from Mendelian expectations because of incomplete dominance, epistasis, or hierarchy of dominance Use pedigree analysis to calculate the likelihood an individual will have a particular genotype or phenotype Week 2 clicker questions 3/20/23, 10:20 AM
Midterm I: 23W-LIFESCI-7B-LEC-1 Genetics, Evolution, and Ecology [Questions 27 - 30] Two generations of a family are depicted in this pedigree. The gel below shows the banding pattern for two VNTRs,
A
and
B
, each with three alleles (denoted
A
,
A
,
A
and
B
,
B
,
B
, respectively). A and B loci are linked on the same chromosome. Some individuals in the pedigree are also affected with an autosomal dominant disorder, and the gene for the disorder is also very close to both molecular markers. Affected individuals in the pedigree are shown by filled symbols. 1
2
3
1
2
3
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3 / 3 pts Question 27 Allele B2 could be a marker for the disorder. True Correct! Correct! 3/20/23, 10:20 AM
Midterm I: 23W-LIFESCI-7B-LEC-1 Genetics, Evolution, and Ecology False Evaluate whether a specific SNP or VNTR is associated with a specific disease Analyze VNTR DNA fingerprinting data to determine the genotypes and/or relatedness of individuals Determine if and where homologous recombination has occurred based on combinations of linked alleles Visualize how meiosis produces four haploid gametes CQs Week 3 PEQs Week 3 0 / 3 pts Question 28 The genotype of individual 3 is: A2B1/A1B3 orrect Answer orrect Answer A1A2/B1B3 ou Answered ou Answered A2B3/A2B3 A1B1/A2B3
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3/20/23, 10:20 AM
Midterm I: 23W-LIFESCI-7B-LEC-1 Genetics, Evolution, and Ecology Evaluate whether a specific SNP or VNTR is associated with a specific disease Analyze VNTR DNA fingerprinting data to determine the genotypes and/or relatedness of individuals Determine if and where homologous recombination has occurred based on combinations of linked alleles Visualize how meiosis produces four haploid gametes CQs Week 3 PEQs Week 3 3 / 3 pts Question 29 Individual 3 must have inherited a recombinant chromosome from their XX parent. True False Correct! Correct!
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3/20/23, 10:20 AM
Midterm I: 23W-LIFESCI-7B-LEC-1 Genetics, Evolution, and Ecology Evaluate whether a specific SNP or VNTR is associated with a specific disease Analyze VNTR DNA fingerprinting data to determine the genotypes and/or relatedness of individuals Determine if and where homologous recombination has occurred based on combinations of linked alleles Visualize how meiosis produces four haploid gametes CQs Week 3 PEQs Week 3 3 / 3 pts Question 30 Individual 1 inherited from their XX parent a chromosome with which of the following combinations of alleles? A1B2 Correct! Correct! A2B2 A1B3
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A2B3 3/20/23, 10:20 AM
Midterm I: 23W-LIFESCI-7B-LEC-1 Genetics, Evolution, and Ecology Evaluate whether a specific SNP or VNTR is associated with a specific disease Analyze VNTR DNA fingerprinting data to determine the genotypes and/or relatedness of individuals Determine if and where homologous recombination has occurred based on combinations of linked alleles Visualize how meiosis produces four haploid gametes CQs Week 3 PEQs Week 3 0 / 3 pts Question 31 [Question 31] In a particular strain of mice,
Gene M
controls fur color, and brown is dominant to white;
Gene N
determines a recessive genetic disorder. A particular group of brown mice without the disorder are known to have identical genotypes for these two genes. These mice were bred with a group of white mice with the disorder. The numbers of offspring with particular phenotypes are shown in the table.
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Based on these results, which of the diagrams below best characterizes the arrangement of these genes and alleles on the chromosomes of this group of mice? (Chromosomes shown as white bars, and genes as black bars crossing them.) (Ignore mutation and crossing-over.) 3/20/23, 10:20 AM
Midterm I: 23W-LIFESCI-7B-LEC-1 Genetics, Evolution, and Ecology Diagram B ou Answered ou Answered Diagram A Diagram E Diagram D orrect Answer orrect Answer Diagram C Determine if and where homologous recombination has occurred based on combinations of linked alleles Visualize how meiosis produces four haploid gametes 3 / 3 pts Question 32 [Question 32] Genes A, B and C are all linked on the same chromosome. The results of hundreds of matings show recombination between all of
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these genes. The recombination frequency between gene A and gene B is 16.8%, the recombination frequency between gene A and gene C is 21.1%, and the recombination frequency between gene B and gene C is 4.3%. Which of these is the correct order of these genes along this chromosome? ACB ABC Correct! Correct! 3/20/23, 10:20 AM
Midterm I: 23W-LIFESCI-7B-LEC-1 Genetics, Evolution, and Ecology BAC Determine if and where homologous recombination has occurred based on combinations of linked alleles Calculate genetic map distances among linked genes from the frequencies of progeny with recombinant phenotypes, and construct a genetic map from data provided Week 2 and 3 clicker questions Quiz Score:
78
out of 96
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