Chapter 12 Answers-Transport
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Chapter 12 Membrane Transport
1: Which of the following channels would not be expected to generate a change in voltage by movement of its substrate across the membrane where it is found?
a.
an aquaporin
b.
a sodium channel
c.
a calcium channel
d.
a proton channel
ANS: A
Aquaporin channels are found in the plasma membrane of some cells, where they facilitate the diffusion of water across the membrane. Because water is an uncharged molecule, its movement would not be expected to alter the voltage across the membrane.
DIF: Easy REF: 12.1 OBJ: 12.1.k Describe the ways in which water can move across cell membranes and articulate what governs whether water will enter or exit a cell. MSC: Understanding
2: Below is a list of molecules with different chemical characteristics. Knowing that all molecules will eventually diffuse across a phospholipid bilayer, select the option below that most accurately predicts the relative rates of diffusion of these molecules (fastest to
slowest).
alanine estrogenpropanolsodium
a. alanine >
propanol >
sodium >
estrogen
b. sodium >
propanol >
alanine >
estrogen
c. estrogen >
propanol >
sodium >
alanine
d. estrogen >
propanol >
alanine >
sodium
ANS: D
Estrogen is a steroid hormone and will diffuse the fastest across the membrane. Propanol
is a small, uncharged molecule with a polar group. Alanine is an amino acid, and although it has a small, nonpolar side group, amino acids are charged molecules. Sodium
is an ion and will move the slowest across the bilayer.
DIF: Easy REF: 12.1 OBJ: 12.1.c Review the properties that govern the rate at which a given solute can cross a protein-free lipid bilayer. MSC: Understanding
3: Cells use membranes to help maintain set ranges of ion concentrations inside and outside
the cell. Which of the following ions is the most abundant inside a typical mammalian cell?
a. Na
+
b. K
+
c. Ca
2+
d. Cl
−
ANS: B DIF: Easy REF: 12.1 OBJ: 12.1.e Indicate how the concentration of ions in the cell differs from that outside the cell. MSC: Remembering
4: Cells use membranes to help maintain set ranges of ion concentrations inside and outside
the cell. Which of the following ions is the most abundant outside a typical mammalian cell?
a. Na
+
b. K
+
c. Ca
2+
d. Cl
−
ANS: A DIF: Easy REF: 12.1 OBJ: 12.1.e Indicate how the concentration of ions in the cell differs from that outside the cell. MSC: Remembering
5: Which of the following statements about resting membrane potential is true?
a.
The resting membrane potential for most animal cells is 0 mV, because the positive and negative ions are in balance.
b.
The resting membrane potential for most animal cells is positive, because Na
+
ions are so plentiful inside cells.
c.
The resting membrane potential for most animal cells is negative, because the inside of the cell is more negatively charged than the outside of the cell.
d.
At the resting membrane potential, no ions enter or exit the cell.
ANS: C DIF: Easy REF: 12.1 OBJ: 12.1.f Define “resting membrane potential.” MSC: Understanding
6: A hungry yeast cell lands in a vat of grape juice and begins to feast on the sugars there, producing carbon dioxide and ethanol in the process:
C
6
H
12
O
6
+
2ADP +
2P
i
+
H
+
→
2CO
2
+
2CH
3
CH
2
OH +
2ATP +
2H
2
O
Unfortunately, the grape juice is contaminated with proteases that attack some of the transport proteins in the yeast cell membrane, and the yeast cell dies. Which of the following is the most likely cause of the yeast cell’s demise?
a.
toxic buildup of carbon dioxide inside the cell
b.
toxic buildup of ethanol inside the cell
c.
diffusion of ATP out of the cell
d.
inability to import sugar into the cell
ANS: D DIF: Moderate REF: 12.1 OBJ: 12.1.g Compare how transporters and channels discriminate among solutes, moving only a select subset across the membrane. MSC: Applying
7: Some cells express aquaporin proteins—they are channel proteins that facilitate the flow of water molecules through the plasma membrane. What regulates the rate and direction
of water diffusion across the membrane?
a.
aquaporin conformation
b.
resting membrane potential
c.
solute concentrations on either side of the membrane
d.
availability of ATP
ANS: C DIF: Easy REF: 12.1 OBJ: 12.1.k Describe the ways in which water can move across cell membranes and articulate what governs whether water will enter or exit a cell. MSC: Remembering
8: Pumps are transporters that are able to harness energy provided by other components in the cells to drive the movement of solutes across membranes, against their concentration gradient. This type of transport is called
a.
active transport.
b.
free diffusion.
c.
facilitated diffusion.
d.
passive transport.
ANS: A DIF: Easy REF: 12.1 OBJ: 12.1.h Distinguish between active and passive transport and indicate which type of membrane transport protein carries out each. MSC: Remembering
9: You have generated antibodies that recognize the extracellular domain of the Ca
2+
-pump. Adding these antibodies to animal cells blocks the active transport of Ca
2+
from the cytosol into the extracellular environment. What do you expect to observe with respect to intracellular Ca
2+
?
a. Ca
2+
-pumps in vesicle membranes keep cytosolic calcium levels low.
b. Ca
2+
-pumps in the endoplasmic reticulum membrane keep cytosolic calcium levels low.
c. Ca
2+
-pumps in the Golgi apparatus keep cytosolic calcium levels low.
d. Ca
2+
concentrations in the cytosol increase at a steady rate.
ANS: B
In addition to the Ca
2+
-pumps in the plasma membrane, Ca
2+
-pumps are also found in the membrane of the endoplasmic reticulum (ER). Those in the ER membrane will continue to
remove calcium ions from the cytosol, keeping calcium levels low.
DIF: Moderate REF: 12.2 OBJ: 12.2.e Explain why—and how—cells keep the cytosolic concentration of calcium ions low. MSC: Applying
10: Cells make use of H
+
electrochemical gradients in many ways. Which of the following proton transporters is used to regulate pH in animal cells?
a.
light-driven pump
b. H
+
ATPase
c. H
+
symporter
d. Na
+
-H
+
exchanger
ANS: D
The high extracellular concentration of Na
+
is employed by a transporter that pumps protons out of animal cells as Na
+
is brought into the cell. The other transporters are found only in bacterial cells.
DIF: Easy REF: 12.2 OBJ: 12.2.h Express how the sodium–proton exchanger in the plasma membrane allows animal cells to control the pH of their cytosol. MSC: Remembering
11: Ca
2+
-pumps in the plasma membrane and endoplasmic reticulum are important for
a.
maintaining osmotic balance.
b.
preventing Ca
2+
from altering the activity of molecules in the cytosol.
c.
providing enzymes in the endoplasmic reticulum with Ca
2+
ions that are necessary for their catalytic activity.
d.
maintaining a negative membrane potential.
ANS: B
The major purpose of the Ca
2+
-pumps is to keep the cytosolic concentration of Ca
2+
low. When Ca
2+
does move into the cytosol, it alters the activity of many proteins; hence, Ca
2+
is a powerful signaling molecule.
DIF: Easy REF: 12;2 OBJ: 12.2.e Explain why—and how—cells keep the cytosolic concentration of calcium ions low. MSC: Remembering
12: Which of the following occur WITHOUT coupling transport of the solute to the movement of a second solute?
a.
import of glucose into gut epithelial cells
b.
export of Ca
2+
from the cytosol
c.
export of H
+
from animal cells for pH regulation
d.
the export of Na
+
from cells to maintain resting membrane potential
ANS: B
Ca
2+
is exported using ATP-powered pumps. There are no other solutes that are being moved by these pumps.
DIF: Easy REF: 12.2 OBJ: 12.2.a Outline how the glucose transporter in the plasma membrane of mammalian cells imports glucose after a meal and exports glucose to provide fuel for other tissues in the body. | 12.2.e Explain why—and how—cells keep the
cytosolic concentration of calcium ions low. | 12.2.h Express how the sodium–proton exchanger in the plasma membrane allows animal cells to control the pH of their cytosol. MSC: Understanding
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Related Questions
A8.
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( Notes
1.Explain what will happen to an animal cell
when it is placed in a solution that has a
greater solute concentration than that inside
the cell.
2.How will a plant cell that is subjected to a
solute concentration that is less than that
of inside the cell will react?
3.What is the importance of the concentration
gidient in passive transport?
4.in which type of transport does the working
mechanism of a sodium-potassium
pump belongs to? Explain,
5.How do secretory cells perform exocytosis?
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1. Name the two forms of passive transport.
2. With reference to a named, specific example, describe the processes involved in channel mediated diffusion. In your answe state what kind of transport it is.
3. Explain why the graph obtained for facilitated diffusion when velocity of transport of a given molecule is plotted against its concentration is a hyperbola. In your answer, highlight the events that occur along the hyperbola.
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Item11
Item 11
The sodium-potassium ATPase functions by performing
Multiple Choice
a. primary active transport.
b. secondary active transport.
c. exocytosis.
d. both exocytosis and endocytosis.
e. receptor-mediated endocytosis.
Item12
Item 12
The uptake of cholesterol into cells is an example of
Multiple Choice
a. phagocytosis.
b. pinocytosis.
c. receptor-mediated endocytosis.
d. receptor-mediated exocytosis.
e. simple diffusion.
Item13
Item 13
The sodium-potassium pump moves
Multiple Choice
a. sodium and potassium into the cell.
b. sodium and potassium out of the cell.
c. sodium into the cell and potassium out of the cell.
d. sodium out of the cell and potassium into the cell.
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4. The graph below represents two different modes of transport across a biological membrane. One employs a
membrane protein and the other does not. Which line represents transport with a membrane protein? Label
each line with the mode of transport. There are three key characteristics of transport across a biological
membrane using a membrane protein. What are these three key features? List and describe each feature.
107
A
B
Concentration difference across the mebrane
Rate of Transport
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Matching
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20. Which of the following is NOT true of ABC transport?
A. An example of active transport systems
B. ATP-dependent process
C. Employ carrier proteins
D. It moves molecules against the concentration gradient
E. Observed only in Eukarya
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Jus give all answer only with little bit explanation
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33. Which statements concerning passive and active transport are correct?
A. Both passive and active transport requires cell energy
B. Passive requires cell energy while active transport does not
C. Active transport requires cell energy while passive does not
D. Neither passive nor active transport requires cell energy
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23. Look at the diagram of a cross-section of a cell membrane below.
CELL MEMBRANE
Low Concentration
of Substances
Outside Cell
Cell
Membrane
Inside Cell
High Concentration
of Substances
The molecules in the diagram are moving through a protein channel. What type of cellular transport does this
represent?
a. Passive Transport- Osmosis
b. Passive Transport- Facilitated Diffusion
c. Active Transport- Facilitated Diffusion
d. Active Transport- Endocytosis
Direction of Substance Movement
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rate of transport
Vmax
1/2Vmax
transporter-mecated
diffusion
Km
simple
diffusion
concentration of
transported molecule
The graph at left shows rates of movement
across a cell membrane for a substance
that uses simple diffusion (green) and a
transport mechanism (red). Which of the
following is TRUE about the transporters at
the point shown by the arrow?
A. The transporter proteins are operating
more slowly than at lower
concentrations.
B. The transporter proteins are operating
as fast as possible.
C. The transporters proteins shut off at that
concentration.
D. The rate slows because transporter
proteins run out of ATP.
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Listen The mechanism of membrane transport may involve the following: 1) ATP hydrolysis. O2) Conformation change of membrane proteins. 3) Phosphorylation or dephosphorylation of membrane proteins. 4) ATP hydrolysis and conformation change of membrane proteins. 5) All of these are correct.
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(a)Aquaporins and membrane channel protein in plant and animal,they permit the movement of water across the membrane.Explain why this is necessary.(b) Explain the importance of cell surface membrane to cell
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Osmosis
15. Contrast the following types of solutions:
isotonic -
hypertonic -
hypotonic –
Primary Active Transport
16. Describe primary active transport mechanisms using the sodium-potassium pump as an
example.
Secondary Active Transport
17. a. Define secondary active transport.
b. How does secondary active transport maintain low calcium concentrations in the cytosel
and/or absorption of nutrients into cell?
Endocytosis
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2.
1. Compare and contrast between passive transport, active transport and bulk transport?
Explain (using the correct terminology and drawing an image) what happens to the cells in the
following environments:
a. A human blood cell (0.9% salt) is placed in a salt water tank (27.5% salt).
b. A bacterial cell with 35% organic material in their cytoplasm is living in a tank filled with
35% sulfur.
c. A freshwater plant cell (75% water) is living in a pond that floods over.
3. List and briefly define the two Laws of Thermodynamics (energy).
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Please answer in detail.
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23. Osmotic pressure is the force provided by water molecules as they diffuse through the membrane osmotic pressure is indicated by the height of the water columns observed in this experiment higher columns indicate greater pressure What relationship exists between the difference in the concentration of water on each side of the membrane and the osmotic pressure.
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22. Which of the following statements about passive processes of membrane transport is true?
a. cellular energy is not required
b. substances move along its concentration gradient
c. all require the aid of proteins during transport
d. a and b
e. a and c
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secondary active transport depends on which of the following principles?
a. sodium is pumped out of the cell against a concentration gradient by primary active transport
b. sodium moves out of the cell with a concentration gradient
c. primary active transport is necessary to pump sodium into the cell from a higher to lower concentration
d. diffusion causes sodium to move out of the cell
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Osmosis Practice Activity
Osmosis is the diffusion of water from an area of high concentration to an area of low concentration.
Only water moves in osmosis! The diagrams below show the concentration of water and salt inside
the cell and the concentration of water and salt surrounding the cell. Complete the sentences below
by comparing the concentration of the water inside the cell and the concentration outside the cell.
1.
a. Water will flow
the cell, out of the cell, in both directions).
(into
5% NaCl
95% H20
95% NaCI
5% H20
b. The cell will
(shrink,
burst, stay the same).
a. Water will flow
(into the cell.
2.
5% NaCl
out of the cell, in both directions).
5% NaCl
95% H20
95% H20
b. The cell will
(shrink, burst,
stay the same).
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Terms
Similarity
Difference
Active Transport/Passive
Transport
4. Osmosis - hypertonic/hypotonic/isotonic
Define the following:
Term
Definition
Isotonic
Hypertonic
Hypotonic
Concentration in center of box is the concentration inside the cell. Concentration elsewhere in box is the
concentration outside the cell.
Beaker 1
A. What is the % of water inside the cell?
90% glucose
B. What is the % of water outside the cell?
C. Will osmosis occur?
10% glucose
D. If so, in what direction will osmosis occur?
E. Will glucose diffuse?
F. Will the cell shrink or swell?
G. How do you know?
H. This diagram shows the cell in a(n) (circle one) hypotonic / hypertonic / isotonic solution.
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Liver cells are in contact with the blood and exchange a variety of substances with the blood plasma (the noncellular part of blood). The concentration of water is equal in the cytoplasm of liver cells and in the blood plasma. Explain this observation in terms of membrane permeability and transport mechanisms.
Animal cells typically maintain a higher concentration of Na+ outside the cell and a higher concentration of K+ inside the cell via the Na+-K+ pump. The drug ouabain inhibits the activity of the Na+-K+ pump. A nerve cell is incubated in ouabain. Predict what will happen to the concentrations of Na+ and K+ inside and outside the nerve cell as a result.
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Pertains to membrane transport and signaling
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3. In the following diagram, determine the type of transport protein in A. Justify your answer with
specific reference to the role that Ca²+ and galactose have in this scenario.
Apical
membrane
ATP
2 CI
Basal
membrane
CI™
ADP + Pi
Ca²+
Ca²+
2 Ca²+
Cytosol
Galactose
A
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Part 1: If a gated channel (not a pump) is specific for potassium ions and based on what you know about concentration gradients, when will the potassium ions move through the channel?
a) Is gated channel transport using energy (ATP)?
Part 2: Why does the sodium - potassium pump need to use energy (ATP)?
a) Define active transport in your own words.
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6. For each of the following scenarios described where a molecule or ion is moving from one side
of a membrane to the other, select the method by which the molecule or ion is moving. Each
answer can be used more than once, or not at all.
a. Simple Diffusion
b. Facilitated diffusion by a channel protein
c. Facilitated diffusion by a carrier/transport protein
d. Active transport by a pump
e. Could be B or C, not enough information is given
.
Chloride (Cl-) is an ion that is essential for neuronal signaling and regulating action
potential/excitability in neurons. When chloride receptors are opened with a
neurotransmitter, Cl- flows from high concentration in the synapse (outside of the
cell) to low concentration in the neuron cell.
Oxygen gas must cross from the bloodstream into cells and it has the chemical
structure O=O.
Glucose is a polar molecule that moves from the small intestine, where it is found
high concentra to inside the cells that line the digestive tract, where it is
found…
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Párrafo
Estilos
the glucose molecules are chemically bonded more tightly on one side of the membrane than
on the other.
9. Water moves across a cell membrane through a channel protein, whereas glucose moves across a
cell membrane via a carrier protein. Which statement provides a valid comparison of these two
membrane transport systems?
Glucose moves in a direction from high to low concentration, while water moves in a direction
that is not governed by differing solute concentrations.
Water transport occurs without the cell using energy, whereas glucose transport requires
energy input by the cell.
A cell can add more sites for water transport to increase water movement across the
membrane but cannot achieve the same result for glucose using a similar strategy.
Several water molecules move one after the other through the opening provided by a channel
protein, while glucose is transported across the membrane via a carrier protein one molecule
at a time.
Genetic mutations can alter glucose…
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Please help
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Which of the following statements are correct?
P. Plasma membrane is highly impermeable to all charged molecules
Q. All membrane transport proteins so far known, are transmembrane multipass proteins
R. Ionophores operate by shielding the charge of the transported ion so that it can penetrate the
hydrophobic interior of the lipid bilayer.
S. Na+-K+ ATPase exchanges equal numbers of Na+ and K+ ions in each pumping cycle
P and Q
R and S
P and S
Q and R
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- A8.arrow_forward( Notes 1.Explain what will happen to an animal cell when it is placed in a solution that has a greater solute concentration than that inside the cell. 2.How will a plant cell that is subjected to a solute concentration that is less than that of inside the cell will react? 3.What is the importance of the concentration gidient in passive transport? 4.in which type of transport does the working mechanism of a sodium-potassium pump belongs to? Explain, 5.How do secretory cells perform exocytosis?arrow_forward1. Name the two forms of passive transport. 2. With reference to a named, specific example, describe the processes involved in channel mediated diffusion. In your answe state what kind of transport it is. 3. Explain why the graph obtained for facilitated diffusion when velocity of transport of a given molecule is plotted against its concentration is a hyperbola. In your answer, highlight the events that occur along the hyperbola.arrow_forward
- Item11 Item 11 The sodium-potassium ATPase functions by performing Multiple Choice a. primary active transport. b. secondary active transport. c. exocytosis. d. both exocytosis and endocytosis. e. receptor-mediated endocytosis. Item12 Item 12 The uptake of cholesterol into cells is an example of Multiple Choice a. phagocytosis. b. pinocytosis. c. receptor-mediated endocytosis. d. receptor-mediated exocytosis. e. simple diffusion. Item13 Item 13 The sodium-potassium pump moves Multiple Choice a. sodium and potassium into the cell. b. sodium and potassium out of the cell. c. sodium into the cell and potassium out of the cell. d. sodium out of the cell and potassium into the cell.arrow_forward4. The graph below represents two different modes of transport across a biological membrane. One employs a membrane protein and the other does not. Which line represents transport with a membrane protein? Label each line with the mode of transport. There are three key characteristics of transport across a biological membrane using a membrane protein. What are these three key features? List and describe each feature. 107 A B Concentration difference across the mebrane Rate of Transportarrow_forwardMatchingarrow_forward
- 20. Which of the following is NOT true of ABC transport? A. An example of active transport systems B. ATP-dependent process C. Employ carrier proteins D. It moves molecules against the concentration gradient E. Observed only in Eukaryaarrow_forwardJus give all answer only with little bit explanationarrow_forward33. Which statements concerning passive and active transport are correct? A. Both passive and active transport requires cell energy B. Passive requires cell energy while active transport does not C. Active transport requires cell energy while passive does not D. Neither passive nor active transport requires cell energyarrow_forward
- 23. Look at the diagram of a cross-section of a cell membrane below. CELL MEMBRANE Low Concentration of Substances Outside Cell Cell Membrane Inside Cell High Concentration of Substances The molecules in the diagram are moving through a protein channel. What type of cellular transport does this represent? a. Passive Transport- Osmosis b. Passive Transport- Facilitated Diffusion c. Active Transport- Facilitated Diffusion d. Active Transport- Endocytosis Direction of Substance Movementarrow_forwardrate of transport Vmax 1/2Vmax transporter-mecated diffusion Km simple diffusion concentration of transported molecule The graph at left shows rates of movement across a cell membrane for a substance that uses simple diffusion (green) and a transport mechanism (red). Which of the following is TRUE about the transporters at the point shown by the arrow? A. The transporter proteins are operating more slowly than at lower concentrations. B. The transporter proteins are operating as fast as possible. C. The transporters proteins shut off at that concentration. D. The rate slows because transporter proteins run out of ATP.arrow_forwardListen The mechanism of membrane transport may involve the following: 1) ATP hydrolysis. O2) Conformation change of membrane proteins. 3) Phosphorylation or dephosphorylation of membrane proteins. 4) ATP hydrolysis and conformation change of membrane proteins. 5) All of these are correct.arrow_forward
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