Module 2 Lab Report

An unknown substance "A" was allowed to partition between a mixture of 150 mL water and 80 mL benzene. After titration, you found that 0.75 moles of "A" was dissolved in the water while 0.60 moles dissolved in benzene. Calculate for the partition coefficient of substance "A". What can you infer about the nature of substance "A" based on the value of the partition coefficient?

I need help rewriting this without copying word by word. Could you help me? Could you also use different references from different sources?

Need HELP ASAP Calculate the partition coefficient Kd of X in hexane. Answer in 4 significant figures. Calculate the partition coefficient Kd of X in chloroform. Answer in 4 significant figures.

Three extractions with 50 ml portions of chloroform removed 97% of a solute from 200 ml of an aqueous solution. Calculate the partition coefficient of the solute: KD =Cchloro/Caq- Two weak bases (organic amities) have basic dissociation constants of KbA= 1 x 104 and KbB =1 x 10-8. Both bases have partition coefficients of approximately 10 between chloroform and water. Describe a procedure, making use of the difference in K, for separating the two by extraction. Two weak acids, HX and HY, have partition coefficients, Kp = Cet/Caq, of 5 and 50 respectively, and dissociation constants of 1 x 104 and 1 x 108, respectively. Calculate the distribution ratios of the two acids at integral values of pH of the aqueous solution from pH 4 to pH 11, assuming equal volumes of the two solvents. What is the minimum pH for which the ratio of D values is at least 105?

You add 1 mL of sample and collect 1 mL fractions from a column with a volume of 20 mL where the beads take up 60% of the column and the protein of interest has a partition coefficient of 0.4. What fraction do you want to keep?

what can we discuss/say on solvent polarity with regards to partition coefficient?

Chemistry A 50ml aliquot of a 0.1 M solution of a neutral drug was extracted with 2 x 5 ml ethyl acetate. The drug concentration in the combined organic layers was found to be 0.36 M. Calculate the partition coefficient for this drug under these conditions.

Ethyl heptanoate (EH), a food aroma compound, was added to water and allowed to come to equilibrium with a known volume of air and results showed that its partition coefficient, [EHair]/[EHwater] is equal to 1.8 x 10-2. In the same experiment with oil in place of water, its partition coefficient, [EHair]/[EHoi] is found to be lower at 6.0 x 10-6. Account for the difference between the two values.

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A solution of 3g organic compound X in 200ml of water was extracted with 200 ml of ethyl ether. At equilibrium the concentration of Xin the two phases was ; 2.6g/100ml of ethyl ether ; 0.8g/100 ml of water. Calculate the partition coefficient, Kd, for compound X in the system. Show your calculations and What percentage of the original sample of X was extracted? Show your calculations.

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Simple extractions are particularly useful for separations where only one component has a favorable partition coefficient. True or False?  True  False

Mercury is present in Lake Miramar at a total concentration of 20.4 ng/L. Lab tests suggest an average solids partition coefficient of 105L kg-1  What is the dissolved phase concentration if the particle concentration is 25 mg L-1?

A 78 mg sample of an organic compound (molar mass = 84.0 g/mol) is partitioned between 2.00 mL of water and 2.00 mL of methylene chloride. Separation and processing of the organic phase results in the isolation of 58 mg of the organic compound. Calculate the partition coefficient for the compound between methylene chloride and water (Kpmethylene chloride/water). Your answer should reflect the proper number of significant figures.

A 36.0 mg sample of an organic compound (molar mass = 84.0 g/mol) is dissolved in 10.0 mL of water. This aqueous solution is extracted with 5.0 mL of hexane. Separation and analysis of the aqueous phase shows that it now contains 12.0 mg of the organic compound. Calculate the partition coefficient for the compound between hexane and water (Kphexane/water). Your answer should reflect the proper number of significant figures.

explain flow techniques and relaxation techniques in chemical kinetics?

The octanol - water aqueous buffer partition coefficients (P) for a drug used to treat glaucoma were obtained experimentally at various temperatures (T) and pH values. The results are presented in the following table: pH=7.0 0.72 0.84 pH=6.25 pH=7.25 T= 27 C 0.24 0.89 T= 30 C 0.31 1.06 T= 40 C 1.23 1.49 27.4 mg of this drug were dissolved in 100 mL of buffered water (pH=7.0; T=30) and then partitioned with octanol portions of 37.1 mL. Calculate how many mg of drug will remain in water after in the first extraction (Fill in ONLY numbers approximated to the 2nd decimal place) Answer: 19.01

The following equation describes the dependence of the rate constant (k) with the temperature in dynamic NMR. kgTc -AG*. exp (- RT. k = C where kg and h are physical constants, R is the ideal gas constant, T. is the coalescence temperature and AG* is the activation energy? The following table shows the units of some of these parameters. Parameters Units k s-1 To K h Js R JK-' mol-! AG* J mol- Does k increase with AG*? Explain your answer.

The partition coefficient of iodine between CCl4 and water is Сcc14/CH₂0 = K = 85, where the C₁ represent the concentration in mol/L of iodine in the solvent. (a) If you want to extract 90% of the iodine from 100 mL of an aqueous iodine solution in a single extraction, Calculate the volume of carbon tetrachloride needed. (b) If you want to extract 90% of the iodine from 100 mL of an aqueous iodine solution in two extractions of equal volumes, calculate the volume of carbon tetrachloride needed in each. (c) If ß is the fraction of iodine remaining in the aqueous solution after n extractions with equal volumes of CC14, show that as n→ ∞, the total required volume of CCl4 per unit volume of water for each extraction is given by: Remember that: ln(1+x) ≈ x 2 VCC4,tot VH₂0 + 몰.... 3 In 3 K

Solve using Partition coefficient. A. Single Extraction of 5.0g a caffeine w/ 450mL ether. Inter Given 500mL H₂00 quis k = 5 120 O

Two compounds with partition coefficients of 15 and 18 are to be separated on a column with VSVM=0.30VSVM=0.30.  Calculate the number of theoretical plates needed to produce a resolution of 1.8. Do not worry about significant figures of your final answer.

What volume of chloroform is needed to extract 99.5% of a solute from 200 mL of water, if the partition coefficient is [CHC13]/[CH₂0] = 55? O A. 710 B. 684 C. 724 D. 734

The following equation describes the dependence of the rate constant (k) with the temperature in dynamic NMR. kgTc exp (- -AG* RTc k = h where kg and h are physical constants, R is the ideal gas constant, T. is the coalescence temperature and AG* is the activation energy? The following table shows the units of some of these parameters. Parameters Units k s-l T. K h Js J K-' mol- J mol- R AG+ What are the units of kg? Show your analysis.

Your group was allocated an unknown substance X and instructed to measure its partition coefficient between an organic solvent and water as part of a lab activity. 4 grams of X are dissolved and shaken in a combination of 130 mL benzene and 100 mL water. Finally, your group identified 0.5 g of X in the benzene layer. Calculate the partition coefficient using the information supplied. What can you tell about substance X's chemical composition?

What is the partition Coefficient of phenazopyridine? With illustration