Introduction Lipoprotein A was first discovered in humans by Kare Berg in 1963 whilst a study of variation in LDL antigenicity. The Human gene encoding lipoprotein(a) was cloned in the year 1987(1). Lipoprotein A Structure Lipoprotein A has a similar structure to the LDL molecule with the addition of a covalently bound specific apolipoprotein A (2). Apolipoprotein(A) is a homologue of plasminogen and contains several copies of KRINGLE 4 plasminogen, a single copy of KRINGLE 5 plasminogen and an
PART ONE Medical-Surgical Cases 1 1 Cardiovascular Cardiovascular Disorders Case Study 1 Heart Failure Difficulty: Beginning Setting: Emergency department, hospital Index Words: heart failure (HF), cardiomyopathy, volume overload, quality of life X Scenario M.G., a “frequent flier,” is admitted to the emergency department (ED) with a diagnosis of heart failure (HF). She was discharged from the hospital 10 days ago and comes in today stating, “I just had to come to the hospital today because I
Congestive heart failure, also called heart failure or CHF, is one of the fastest-growing syndromes in the United States and worldwide. It is a condition with high hospitalization and high mortality rates as well as a compound medical regimen that significantly affects the patient’s lifestyle and that of their family. The term alone, “heart failure”, is enough to scare the bravest client and cause the rise of numberless concerns and questions. Patients may worry and exclaim, “Did my heart stop working