Multiple Sclerosis (MS) is an autoimmune demyelinating disorder it is characterized by inflammation and destruction of CNS myelin. It affects approximately 350,000 persons in the united states and more than 1 million worldwide (Porth,2014). The age of onset is typically between 18 and 45 years of age. Women are affected twice more frequently than men. Etiology is the cause or set of causes of a disease or condition. The cause of MS is unknown but it is likely that multiple factors are a cause for it. The first cause is immunologic. Multiple Sclerosis is considered an immune-mediated disease meaning the immune system malfunctions and attacks the central nervous system. Researchers know that the myelin sheath is directly affected, but they do not know what triggers the immune system to attack the myelin. The second possible cause is genetic, several genes play a role in MS. The chance of developing MS is slightly higher if a close relative, such as a parent or a sibling has the disease. According to the Multiple Sclerosis Foundation if one parent has MS, the risk of their children getting it is estimated to be between two and five percent. Many scientist believe that people with MS are born with a genetic susceptibility to react to certain environmental agents. A third possible cause is environmental. Some scientists believe vitamin D may play a role. Studies show that there has been an increase of MS cases in countries that are located further from the equator; people who
MS is characterized by the destruction of myelin, inflammation in the CNS and the formation of lesions in the CNS.
MS is usually occurs at age of 15 to 55 with the average onset at about 30 years of age. Women are twice more likely than men to develop this debilitating autoimmune disease (Love, 2006). Due to the heterogeneity of the disease, where it can affects many sites of the CNS such as the brain cortex, brainstem, spinal cord as well as the optic nerve, thus the clinical symptoms of MS are widely ranged.
Multiple Sclerosis (MS) is a chronic inflammatory disease of the central nervous system. MS affects approximately 3.0 million people globally, with about 300,000 cases in the United States. Twice as many women as men have MS. The average ages for onset of MS is 20-40 years. In MS, cells in the immune system attack and destroy myelin, the fatty tissue surrounding nerve cells (http://www.phylomed.com/MS.html). Scar tissue replaces the myelin, interfering with the transmission of nerve signals and leading to numbness, fatigue, spasticity, loss of muscle control, and various other debilitating symptoms. There are four broad theories
Multiple Sclerosis, commonly known as MS is an autoimmune disease of the central nervous system. Scientists have been studying MS since the 19th century. In MS, the body’s immune system produces cells and antibodies that attack myelin in your brain which is essential for the nerves in your brain and spinal cord to conduct electricity to perform its function. The attack on myelin results in vison loss, paralysis, numbness, muscle weakness, difficulty walking, stiffness, spasms, and bladder and bowel problems. MS has varying degrees of severity and affects people between the ages of 20-50, mostly women. Although there are treatments, there is no cause and cure yet.
In Multiple Sclerosis, an abnormal immune mediated response attacks the myelin coating around the nerves in the nervous system in the body. They also say that Multiple sclerosis is more prevalent in areas farther away from the equator (National MS Society). The environment may even have a small role in the disease. Scientists also believe that Multiple Sclerosis may happen when exposed to different viruses and bacteria. According to PubMed, Infectious pathogens are the likely environmental factors involved in the development of Multiple Sclerosis (PubMed). Multiple Sclerosis is not a contagious disease at all. It is not a genetic
women. Multiple Sclerosis (M.S.) is a disease in which the immune system that is very unpredictable,
Among the many dangerous things that can happen to a human being, the unseen is possibly the most horrifying. That which happens inside your body, goes undetected until it’s too late, and can cause some of the most severe damage. Among many of these ravaging diseases is a destructive abnormal immune-mediated response named Multiple Sclerosis. Multiple Sclerosis(or MS) is a disease that strikes nervous tissue in the brain, and causes severe, irreversible damage.
Multiple Sclerosis; also known as MS, is a chronic and degenerative disease that affects the central nervous system. It is a disease in which the body is attacking its own myelin as if it was a foreign substance. This disease is currently affecting about 2.3 million people in the world (Tran, 2014).
Multiples sclerosis, also known as MS, is a disease in which a patient’s immune system attacks his or her central nervous system. Within the central nervous system, the myelin sheaths of individual nerves are attacked and damaged causing a break in communication between the patient’s brain and his and her body. The location of this disease is within the myelin sheaths on the nerves located in the central nervous system.
“ Multiple Sclerosis is considered an autoimmune disease in which the body's immune system attacks its own tissues.” [1] “In the case of MS, this immune system malfunction destroys myelin (the fatty substance that coats and protects nerve fibers in the brain.”[1] "It isn't clear why MS develops in some people and not others. Researchers believe that a combination of genetics and environmental factors appears to be responsible.”
Multiple Sclerosis, also known as MS, is a disease that obliterates the myelin that surrounds the nerve fibers in the spinal cord and the brain. MS is estimated to affect around 23 million people but it does not affect everyone who possesses it the same. There are four types of MS that one can experience; Relapsing-remitting, Secondary-progressive, Primary-progressive, and Progressive-relapsing.
Multiple Sclerosis also known by the abbreviations (MS) has been known as a devastating disease in which its name literally means many scars. This chronic disease attacks the central nervous system, meaning it affects the brain and the spinal cord and is known as an autoimmune disease. MS happens when your immune system attacks myelin, which is a fatty material that is wrapped around nerve fibers to protect them. Without this outset shell, the nerves become damaged in which scar tissue may form. This damage can produce the brain not to be able to send signals throughout the body to work correctly. In 2007, the World Health Organization (WHO) has estimated that approximately 2.5 million people have MS and over 350,000 people have MS in the
Unfortunately, the exact cause of multiple sclerosis is not known yet however, it is considered an autoimmune disease in which the immune system does not function properly and destroys myelin in the brain. Myelin is the white covering or insulator around the axons or nerve fibers and it is made of proteins and phospholipids. When this myelin is damaged it exposes nerve fibers and they become without the myelin that is supposed to protect it and covers it, this causes messages traveling along the nerve to be slowed, blocked, or damaged and this effects the movement of the patient. Additionally, it is unclear why some people get MS; the causes are unknown, however the factors of increasing the risk of developing the disease could be from mainly
Multiple Sclerosis or “MS” is a very different disease there isn’t an exact cause as to why MS occurs but researchers have stated that it affects the central nervous system of the body so the body is having a disruption of messages that are supposed to be sent to the brain (Danette). The central nervous system is made up of your spine, brain and optic nerves (eye nerves). The immune system become sensitized and will mistakenly attack myelin which is the neurons that let us think, see, speak, hear and feel and when that myelin is attacked at it, it makes those five important functions difficult to do but it’s different for every person (What is MS?).
It is estimated that more than 400,000 Americans are affected with Multiple sclerosis (MS). MS mainly affects the functioning of the nerves which results in the problems like lack of proper vision, weakness, and muscle coordination1. The main source for cause for MS is yet to be known but upon the through research the scientists have found the common factors which indulge this disease are 1) Environmental conditions like temperature 2) Microorganisms like bacteria, virus 3) Genetic factors 2