Aspirin And Plants : Aspirin

Aspirin, Caffeine and Salicylamide were extracted from an over-the-counter pain reliever (BC Powder). These components were separated by manipulating their solubilities by adjusting the acidity and basicity of the solution. By doing this, the three components were forced into conjugate acid (or base) forms, causing selective solubility in either an aqueous or organic solvent. These layers were then separated by use of a separation funnel. Once separated, the components extracted were characterized by measuring the melting point and performing a TLC analysis. Also, the recovered aspirin from the first part of the experiment was recrystallized and compared to that of the

Separation and Purification of the Components of an Analgesic Tablet. Cora Bruno, Lab Section E. Aspirin, Caffeine and Acetaminophen were separated from four analgesic tablets of Excedrin using extraction techniques. 5% wt/vol NaHCO3, 4M HCL, ethyl acetate and deionized water were used to separate the three active components. MgSO4 was used to dry each extraction. Aspirin was isolated using a hot water bath and weighed to determine the percent theoretical recovery and the actual percent recovery of aspirin. After separation, Aspirin (ASA), Caffeine (CAF), and Acetaminophen (ACE) were purified and identified using Thin Layer Chromatography (TLC). Standards and purified ASA, CAF, and ACE were spotted on the silica gel (stationary phase) of the

This experiment involved three steps: synthesis of aspirin, isolation and purification, and the estimation of purity of the final product. The synthesis involved the reaction of salicylic acid and acetic anhydride in the presence of a catalyst, phosphoric acid, H3PO4. When the aspirin was prepared, it was isolated and filtered. The percentage yield of the synthesis was calculated to be 78.42%. The experimental melting point range of aspirin was determined to be 122 -132°C. Due to its wide range, and lower value than that of the theoretical melting point of 136°C, it was

Hofmann worked for Bayer, which then named acetylsalicylic acid compound aspirin. Aspirin became commercially available in 1899 and today it is estimated that over a trillion aspirin tablets have been consumed by those in need of its curative effects.

Aspirin is one of the most consumed painkillers created up to this date due to its reliability and low expense. It is often used to relieve minor aches and pains, reduce fever and as an anti-inflammatory medication. Due to its wide range of uses, the demand for this pharmaceutical is very high. As a result, manufacturers who produce this drug must be efficient in order to reduce the time taken to produce this drug and produce the in very high quantities.

The purpose of this lab was to synthesize aspirin, determine the theoretical yield, compare the percent yield to the theoretical yield and test the purity of aspirin by adding Iron (III) chloride to the product.

Aspirin also known as acetylsalicylic acid is a salicylate drug, often used as an analgesic to relieve minor aches and pains, as an antipyretic to reduce fever, and as an

problems in 1888. Aspirin was developed in 1899 by Felix Hoffman. Aspirin is a juice from

The situation in this case reflects the drug consumption at will. The case reflects the consumption of white aspirin powder for pleasure and delight by a girl named Winnie, who was caught in the act by a security guard. The self-consumption of aspirin by Winnie is believed to be regarded as an illegal dosage of non-permissible aspirin by Winnie as it is declared a drug by Macquarie Dictionary. Aspirin, also known as acetylsalicylic acid, is a medicinal drug that is prescribed by the medical practitioners in case of treating inflammation and for reducing pain. The common side effects of aspirin dosage include dizziness, depression, nausea, abdominal discomfort and constipation. The over dosage of this drug can result in dangerous consequences

| * 90% of customers uses aspirin based analgesics * Many of them are suffering from side effects such as upset stomach, irritation of the stomach lining, or an allergic reaction. * 10% of customers who generally visited doctors and who get prescription use acetaminophen thorough doctor’s recommendation.

Acetaminophen was added to the British Pharmacopoeia in 1963. It became very popular once it was released. The reason why it became very popular was because it had very few side effects, unlike aspirin which irritated the stomach. The United States use generic versions of the drug. The drug acetaminophen is called paracetamol in countries located outside of the United

Acetaminophen also known as paracetamol and APAP, is a prescription and over-the-counter drug that is used to treat moderate pain and reduce fever. It is also paired with other ingredients. For example, acetaminophen is mixed with guaifenesin and phenylephrine to make the allergy medication Mucinex, acetaminophen is also used in over 600 other medications. When mixed with an opioid, such as, tramadol, it can be used to treat more severe pain. It is usually taken through the mouth but it can also be taken through injection and as a

Aspirin: A mainstay at pharmacies ever since its invention, aspirin is great for fevers, colds, and headaches. It even reduces the risk of heart attacks, but like ibuprofen, it's hard on the stomach.

Aspirin is a nonopioid analgesic, which acts on the peripheral nerve ending to relieve to minor pain (Heaves, 2015). The pharmacological effects of aspirin include anti-inflammatory, antiplatelet, antipyretic, analgesic. Bayer Aspirin Regimen Adult Low Strength and St Joseph Adult Aspirin are two brand names that aspirin is available in over the counter. Aspirin in low concentration can be used for prevention of cardiovascular disease (Lexicomp, 2016).

This report presents the synthesis of Aspirin (acetylsalicylic acid), as the product of the reaction of salicylic acid with ethanoic anhydride under acidic conditions. Aspirin was purified through recrystallisation by vacuum filtration, followed by desiccation of the Aspirin crystal over silica gel. The percentage yield was calculated as 44.89% and a sample of Aspirin was analysed using infra-red spectroscopy and compared to the spectrum of pure Aspirin, this served as an introduction to the identification of functional groups in organic compounds. The melting point was calculated using an IA9000M apparatus and recorded to be 35.2°C, which was slightly below the melting point of pure Aspirin; known to be between 138-140°C. Both IR spectroscopy and melting point measurement were used verify the purity of synthetic Aspirin made, which proved to be fairly pure under these laboratory conditions.