Diabetes mellitus is a disease marked by high levels of blood glucose or blood sugar. Chronic hyperglycemia with disturbances of carbohydrate, fat, and protein metabolism resulting from defects in insulin production or secretion, insulin action, or both. According to Centers for Disease Control and Prevention (2011), Diabetes is the leading cause of kidney failure, non-traumatic lower extremities amputations, and new cases of blindness among adults in the United States. It is also known as a major cause of heart disease and stroke. It is the known as the seventh leading cause of death in the United States (CDC, 2011).
Every time we eat, our food is digested, and converted into glucose or sugar. As the blood sugar level rise, the
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Normal fasting glucose plasma is less than 100mg/dL (LeRoith, Taylor, & Olefsky, 2004). Typical symptoms of diabetes are excessive urination (polyuria) which occurs because of glycosuria, excessive thirst (polydipsia) which occurs in response to dehydration, and excessive hunger (Polyphagia), which occurs because of persistent loss of calories as a result of glycosuria and the possible effects of diabetes on satiety signals in the brain (Niewoehner, 2004). Other typical signs and symptoms of Diabetes Type 1 are weight loss, fatigue, increase frequency of infections, and rapid onset.
Type 2 Diabetes is also known as adult onset diabetes or non-insulin dependent diabetes. It results from a progressive secretory defect of the pancreatic Beta cell on the background of insulin resistance (Meeking, 2011). Insulin resistance is a disorder in which the cells do not use insulin properly; as the need for insulin rises, the pancreas gradually loses its ability to produce insulin.
The most common risk factors for Type 2 Diabetes are old age, obesity, family history of diabetes, history of gestational diabetes, impaired glucose metabolism, and physical activity. Natural history of type 2 diabetes is variable resulting from long duration of silent hyperglycemia (Meeking, 2011).
Diet is the basic part of management of diabetes. The goal of dietary treatment is to ensure weight control, allowing good, adequate glycemic control with blood glucose levels as close to normal
The body regulates the blood glucose levels by producing insulin. Insulin is a chemical messenger essential for the entry of glucose into a cell. When the pancreas fails to produce insulin that is sufficient to use, the level of glucose in the blood will remain high. If to much insulin is produced, or given through medication, the level of glucose in the blood will remain low. In type 2 diabetes the cells become resistant to insulin and ignore its message to be absorbed into the cells, this is known as insulin resistance. Insulin deficit results in decreased transportation of glucose from cells in the body, hyperglycemia then arises causing to much glucose to be present in the bloodstream (Gould and Dyer, 2011: 550). The pancreas is located
The overwhelming majority of diabetes sufferers have Type 2 diabetes, usually caused by obesity. Non-insulin dependent diabetes has a genetic predisposition and has a peak age onset between 50-60 years of age. In Type 2 diabetes, the body is not able to utilize insulin properly because of insulin resistance. Type 2 diabetes can be controlled with diet, exercise, and medications when necessary. An approach to adopting a healthy lifestyle as a treatment for this disease is encouraged in both types.
Diabetes, also known as Diabetes mellitus, is an incurable disease that happens when the body is unable to properly use and store glucose. Glucose is a form of sugar that gives your cells energy. In Diabetes, however, that same glucose is not neutralized by insulin and therefore is rejected by the cells. Thus leading it to backing up into the bloodstream, resulting in your blood sugar getting too high. This can be from one of two problems. One of them being, the pancreas (the pancreas is about a six inch organ that rests on the back of the abdomen.) cannot produce enough insulin or it cannot produces. Or two, the cells cannot respond to the insulin, and in other cases, both. For a person who doesn 't have diabetes, after they eat the new food they used to fuel their bodies with is neutralized by insulin and that let’s the glucose to enter your cells giving you energy. For a person who does have diabetes however, their bodies are different. Their bodies cannot produce insulin to treat that glucose and therefore cannot have energy. Not to mention, with the glucose being rejected by the cells, it has to go somewhere else.This meaning that the glucose goes into
The symptoms of type 1 diabetes are sudden with onset and may include excessive thirst, frequent urination, bedwetting in children who previously didn’t wet the bed during the night, increased hunger, unintended weight loss, restlessness, and other mood changes, fatigue and weakness, blurred vision, in females- a vaginal yeast infection. The symptoms for type 2 diabetes may not be detected or may be absent making it difficult to diagnose. Symptoms include
Most symptoms of type two diabetes occur when blood sugar levels are abnormally high. The most common symptoms of type two diabetes include excessive thirst, as your tissues become dehydrated, you will become thirsty and fatigue, feeling worn down. Glucose is normally one of the body’s main sources of energy. When cells cannot absorb sugar, you can become fatigued or feel exhausted. Blurred Vision, high glucose levels can cause a swelling of the lens in the eye. This leads to blurry vision. Unfortunately the is no cure for diabetes, but there are simple strategies that may help reduce the risk of developing diabetes by eating healthy, exercising, maintaining a healthy weight and if diet and exercise aren't enough to manage your diabetes, there diabetes medications or insulin shots to manage your blood sugar.
It’s estimated that more than 16 million Americans have been diagnosed with diabetes. And nearly one in five people over 65 years of age is likely to be diagnosed with diabetes. There are 2 types of diabetes: Type 1 and Type 2. Type 1 diabetes, also known as juvenile diabetes, is usually diagnosed in children and young adults. In type 1 diabetes, the body does not produce insulin. In type 2 diabetes the most common form of diabetes, occurs when the body develops insulin resistance. Insulin resistance is when the body does not use insulin properly. This is called insulin resistance. At first, your pancreas makes extra insulin to make up for it. But, over time it isn't able to keep up and can't make enough insulin to keep your blood glucose
Type 2 diabetes is a chronic condition, in which the body has problems regulating sugar. People with diabetes have high blood sugar because their bodies do not produce enough insulin or their cells are non-responsive to insulin. Type 2 diabetes specifically, does not produce enough insulin for your body to break down sugar. According to the National Diabetes Statistic Report of 2014, over 29 million people that live in the United States have a form of diabetes. It is more common in men than woman and is most affected in people from the ages of 45-64. Diabetes is a serious disease and is only increasing in America each year (NDSR, 2014).
Normally when we eat food, in particular carbohydrates (starches and sugars) the level of glucose in our blood increases. In response to this the pancreas produces insulin which brings the level of glucose back to normal. Insulin is a hormone which is produced by a small organ in the body called the pancreas.
There are million of people that are diagnosed of diabetes in United States, mainly Type 2 DM. Some major factors are history of DM in parents or siblings, obesity, physical inactivity and race. Other risk factors are a person that has hypertension,
Diabetes is often referred by doctors as diabetes mellitus. It is a group of metabolic diseases in which the person has high blood glucose, either because insulin production is insufficient or because the body’s cells do not respond properly to insulin. Insulin is necessary to keep blood glucose level stable in the body, It is a hormone produced in the islets of langerhans in the pancreas, it is important for metabolism and utilization of energy from the ingested nutrients especially glucose (DiabetesUK).
Type 2 diabetes is also known as adult-onset or noninsulin-dependent diabetes. It is a condition that affects the way your body breaks down sugar which is your body 's key source of energy. “In people with this condition, the pancreas cannot secrete enough insulin to compensate for the IR (insulin resistance), which
As we all know diabetes is a very well-known health disorder known around the world. Diabetes is a disorder of metabolism in which the body’s inability to produce any or enough insulin causes elevated levels of glucose in the blood. An estimated 23.6 million people in the United States have diabetes, a serious, lifelong condition. Half of the diabetic population have been diagnosed with this specific condition while others have not. Every year, about 1.6 million people aged 20 or older are diagnosed with diabetes. Furthermore, our bodies use digested food for growth and energy so our bodies can maintain a steady metabolism. Most of the food we eat is broken down into glucose, which is a form of sugar in the blood. Glucose is the main
There are three known aspects of diabetes. Type 1, Type 2, and gestational diabetes. Type 1 diabetes that some people call “juvenile diabetes” occurs in children and young adults. The symptoms for Type 1 diabetes are frequent urination, extreme thirst and hunger, unusual weight loss, and exhaustion. Young adults are able to
The treatment of diabetes is dependent on its type and its severity, insulin, exercise, and a diabetic diet is used to treat type 1 diabetes, whiles type 2 diabetes is initially controlled with weight loss, type 2 diabetic diet and physical activity; when these initiatives fail to balance elevated blood sugars, oral medications are prescribed and if that proves few futile then insulin and multiple injectable medications are introduced (Medicinenet2). One cannot prevent type 1 diabetes; however, one can prevent type 2 diabetes by sustaining a balanced weight and engaging in regular physical activity (Medicinenet2). I will conduct an investigation to determine whether Insulin used in the
Hickey et al. (1998) compared 6 women who had undergone gastric bypass and achieved a stable weight to a control group of 6 other women who had achieved the same weight through non-surgical conventional methods thus isolating food-route as the only differing factor. Food bypassed the foregut (distal stomach, antrum, duodenum and proximal jejunum) in the surgical group. Serum leptin, fasting plasma insulin and fasting plasma glucose were all lower in the surgical group than the control group with insulin sensitivity higher in the surgical group. Faraj et al. (2003) hypothesised that the bypass of the distal stomach (and foregut) in a RYGB reduces circulating ghrelin and increases plasma adiponectin not only aiding in weight loss after bypass surgery but causing the alterations in hormones that lead to the alterations in glucose metabolism and insulin sensitivity. Hanusch-Enserer and Brabant (2003) confirmed that grehlin concentrations were not decreased after adjustable gastric banding explaining why although both procedures reduce stomach volume, there is an underlying mechanism to explain the increased efficacy of the RYGB in resolving metabolic disease. However, it cannot be said that LAGB does not resolve metabolic disease because Dixon et al. (2003) found significant improvements in insulin sensitivity and beta-cell function one year after LAGB surgery.