Characteristics Of The Functional Area Of Human Genome

2127 Words Aug 20th, 2014 9 Pages
This has been known from decades that the small segment of human genome is formed of protein sequences while some of the non coded DNA indicates biological functions. Along with the coding of genomes, they are also consisted of sequence which is transcript into RNA like tRNA, rRNA .New challenges of these sequences in the non protein are most prevalent. They are known to identify the functional area in the human genome which is studied by (ENCODE) project. The characteristics which are acting upon the regulatory variations amongst the human beings is elusive due to the difficulty in explaining the functional DNA.Genomic scale maps are combine with Regulatory DNA from 138 cells along with the genomic sequences. This is an initiative to decrease the variety of patterns in regulation of genetic variations of human beings.Harbor is able to work more functionally in the DNA as compared to the protein coded areas. But some effect of the same has been observed in their sizes.Heterogenicity is the stage of functional constraint of the regulatory DNA in which there are different cell types.

A strong approach is required to find out the conservation of DNA which is functionally more important but the fraction of these sites is encodes the practical forms of transcriptional control elements. Some of the other data indicates that large of this proportion is specific for regulatory elements (Dermitzakis and Clark 2002; The ENCODE Project Consortium2007, 2012; Blow et al. 2010; Schmidt…

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