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Dapsone Research Paper

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Leprosy or Hansen’s disease can be treated by a multi-drug therapy, which consists of three drug prescriptions of Dapsone, Rifampicin, and Clofazimine, for at least 24 months. Dapsone is given in 100 mg tablets, Rifampicin 10 mg tablets, and 50mg tablets of Clofazimine. Dapsone acts as a mycobacterial bactericidal or bacteriostatic. Adverse reactions with dapsone are hemolysis, methemoglobinemia, and leukopenia. Contraindications include hypersensitivity to the components of the drug or the drug itself. Nursing considerations for dapsone are treating a patient’s anemia complications first before letting the doctor prescribe, and observe for toxic epidermal necrolysis. Rifampicin will inhibit DNA dependent RNA polymerase, also making it

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