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Microscopic And One Celled Organisms

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I. Introduction A. Question (s) 1. What are parasites a. A parasite lives within or on a separate organism it acquires benefits at the hosts expense i. Protozoa are microscopic and one celled organisms ii. Helminths are large and are multicellular organisms that can be seen by the naked eye during its adult stages iii. Ectoparasites usually serve as vectors and are the cause of much mortality because of disease they spread 2. Affect on organism a. Survival and transmission i. Protozoa is able to reproduce inside humans contributing to their survival can be free living or parasitic in nature ii. Helminths also can be free living or parasitic in nature but once they reach adulthood they cannot reproduce in humans iii. Ectoparasites …show more content…

found in Central West Africa and South Pacific islands C. Life cycle 1. Symptoms a. Reoccurring attacks i. Shaking chills ii. As body temperature declines sweating increases iii. High fever 2. Effect on host a. Organ failure and coma 3. Transmission a. Vector is Anopheles mosquito b. Can be passed to other humans through blood transfusions D. Cure 1. Drugs against Plasmodium a. Combination therapy 2. Resistance E. Null Hypothesis 1. No difference in mechanism used in resistance F. Alternative 1. Is a difference in mechanism used in resistance II. Compare and contrast A. History of Resistance 1. Region where resistance started a. Cambodia-Thailand border i. Artemisinin resistance started here 2. Regions where resistance is more prominent B. Treatment Failure 1. Correct dosage not used a. Patients do not follow through with complete treatment 2. Poor drug quality 3. Rapid Elimination from body a. Patients are so sick they may vomit and not allow proper absorption of the medicine C. Causes of resistance 1. Mutations in parasite strains a. Genetic event causes parasite to be resistant and then these resistant parasites are selected for i. Genetic mutations occur independently from the drug 2. Drug-resistant parasite selected over sensitive parasites a. Selection of drug-resistant mutant happens when the parasite is exposed to subtherapeutic drug concentrations i. If not treated with proper drug

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