Pharyngitis Case Study

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1.1 Introduction Both Pharyngitis and Tonsillitis are two common upper respiratory tract infections (URTI) causing ill health in children presenting to primary care physicians (West, 2002).` Pharyngitis in most cases is quite painful, and is the most common cause of sore throat, can be chronic or acute. Pharyngitis can result in very large tonsils, which cause trouble in swallowing and breathing (Marx and John, 2010). It can be caused by infectious agents (viruses, bacteria and fungi) or physicochemical factors (such as smoking, snoring, shouting, tracheal intubation, medications, or concomitant illness) or environmental factors (including indoor and outdoor air pollutants, temperature and humidity, and hazardous or…show more content…
The success of (GABHS) as a pathogen relies on the production of multiple virulence factors involved in various aspects of host-pathogen interactions. GABHS Pharyngitis is most common in individuals aged 5-15 years, although adults may also acquire the disease (Tart et al., 2007 ; Alter et al., 2011). Streptococcal Pharyngitis seems to be very uncommon in children younger than 3 years with the exception of children with risk factors such as an older close or household contact with group A β-hemolytic Streptococci (GABHS) infection (Centor et al.,…show more content…
Staph. aureus is a frequent resident of human nose and skin in many individuals (Brook and Foote, 2006 ; Wos-Oxley et al., 2010). It is able to cause a large diversity of both benign and lethal infections in humans and animals because of a wide range of virulence factors that include various toxins and enzymes. It also has a major impact as a causative agent of a variety of serious infections including those of the skin and soft tissue (Bal and Gould, 2005 ; Miller and Kaplan, 2009). This species is predominant specially in recurrent patients. Long term persistence is likely be due to an intracellular location rather than biofilm formation. Staph. aureus isolates did not offer a straight forward conservative approach to eradicate the bacteria from their intracellular asylum (Zautner et al.,
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