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Physiological Adaptation Lab Report

Decent Essays

Physiological Adaptations to Oxygen Changes in Diving Mammals
Diving mammals adapt to oxygen and pressure changes during diving by several mechanism. To pressure changes, diving mammals adapt to the direct or mechanical effects of pressure and associated problems such as increased solubility of gases such as Nitrogen and Oxygen, which occur as pressure increases (Li, Morris & Lee, 159). Diving mammals adapt to breath-holding or oxygen deprivation by modifying their metabolism, blood circulation and their capacity to store oxygen (Terrie, 166). For quite some time, the role of globins in oxygen regulation has been researched and known to biologists and other disciplines. However, for a long time, it was assumed that only myoglobin and hemoglobin are the only globins in vertebrates (Costa, 5).

Neuroglobin (Ngb)
At the beginning of the 21st century, through a process of mining the genome sequence, biologists discovered a new type of globin; neuroglobin. The discovered globin was distinctive in its favored expression in the …show more content…

Watanabe et al (2012) conducted a study based on the premise that mammalian neuroglobin (Ngb) is integral to neuroprotection in conditions of oxidative stress. In other terms, neuroglobin (Ngb) prevents cell death during oxidative stress. In their study, Watanabe (2012) established that in conditions of oxidative stress, neuroglobin acts as a guanine nucleotide dissociation inhibitor to repress the activation of Gαi/o. Nevertheless; neuroglobin has to be recruited to lipids through its interaction with flotillin-1. Though the study was conducted on human beings, more recent studies have established that neuroglobin is a neuroprotective mechanism not only for human beings but also for other mammals, especially cetaceans that dive to deep ends of water bodies where they are deprived of

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