Polycystic Ovary Syndrome (PCOS Study

Hyperandrogenism often presents itself in the physical form with acne, hirsutism (male-patterned hair growth), and alopecia. While insulin resistance is typically present in a patient with a higher BMI, 70% of women with PCOS have this condition, putting them at a higher risk of developing Type 2 diabetes (Goodarzi et al., 2011). Other metabolic complications can occur with PCOS, including hypertension and dyslipidemia (Madnani, 2013). The hormonal secretions of the body’s endocrine glands are affected by the hormonal secretions of the ovaries and vice versa via feedback mechanisms. The disruption of normal hormone secretions, particularly hypersecretion of luteinizing hormone (LH), can reduce the chance of conception and increase the risk of miscarriage (Balen,

Polycystic Ovary Syndrome is a common endocrine disorder that can affect many women. It is also “an incurable disorder that affects 1 in 10 women and over 50% do not know they have it” (PCOS Awareness Association, 2014). An ultrasound exam can reveal that women with PCOS have a collection of follicles on enlarged ovaries. The particular cause of polycystic ovary syndrome is unknown. It could be connected to long-term complications; therefore, doctors recommend weight loss to reduce this risk. Also, early diagnosis and treatment can have an impact on deciphering if a woman will have long-term complications. Such complications include type 2

The motive of this paper is to present a analysis of current research on polycystic ovary syndrome more commonly known as PCOS. Pcos is one the most common endocrine disorders in women of reproductive age, affecting 5-10% of the population. Despite it's prevalence, pcos remains largely unknown. The main focus of this paper will be explaining what PCOS is, the causes, the diagnosis and the treatment of polycystic ovary syndrome.

Some foods, on the other hand, have been shown to increase inflammation and should be avoided,

The summer before my freshman year, I was diagnosed with Polycystic Ovarian Syndrome (PCOS). PCOS is an endocrine disorder that is characterized by fatigue, unmanageable weight, infertility, increased androgen levels, and excess insulin, among others. I was prescribed a medicine called Metformin, which, while considered a medication for Type 2 diabetics, is effective in treating PCOS as well. Later I was also put on a birth control pill to regulate my hormones. Throughout the past three years I have had to learn about nutrition, and specifically a PCOS diet, and exercise and why my body needs proper nutrition and exercise more than others might. This has been difficult for me because even though I consider myself active, I had never before worked out with a purpose to be healthier.

According to PubMed Health, Polycystic Ovary Syndrome (PCOS) is a condition in which women possess abnormally high level of male hormones. The high hormone levels lead to risks of irregular or absent menstrual cycles, insulin resistance, ovarian cysts, issues related to the circulatory system, obesity, heart disease, diabetes and etc. Symptoms differ between each woman therefore, despite research data collected showing that PCOS affects 5-10% of women between the age of 18-44, there are many women who live their lives unaware that they have PCOS. The most common symptoms include: absences of ovulation, high levels of androgen present, and abnormal hair growth. The cause of PCOS is still unknown as more research is much-needed to better understand the disorder.

have a high risk of getting type 2 diabetes. Prediabetes, is a condition in which your blood sugar

One study done on one hundred patients with PCOS showed that administration of metformin and pioglitazone shows 50 percent effectiveness in helping menstrual cycle irregularities by the end of six-months of treatment. Both medications also showed a decrease in LDL and an increase in HDL overall, but this was seen more in the pioglitazone group. This study showed that 64% of women with PCOS also had hyperinsulinism. HOMA-IR, used to assess insulin resistance, was shown to have a 15% decrease with metformin and a 50% decrease in patients who used pioglitazone. Thus, for protection from diabetes pioglitazone may be the better treatment. Ovulation was shown to be restored in up to 56% of patients on metformin and pioglitazone. This study showed that pioglitazone may be a new and better option for treatment of PCOS since it can delay onset of type II diabetes, help with signs of hyperandrogenism, and regulate menstrual cycles (sangeeta,

If a patient complains with the signs and symptoms previously described along with abdominal pain, amenorrhea, or difficulty to conceive, a physician will take these necessary measures to diagnosing PCOS. During a physical examination, lab work will be ordered such as a fasting lipid profile, a glucose test, hormone levels, and an insulin test. The results will give detail information on hormone levels such as prolactin and thyroid levels, FSH to LH ratio and androgen levels. A transvaginal ultrasound will also be recommended and administered to indicate a pearl-necklace pattern of cysts

Although both of these article conclude that hirsutism had the most impact on reduction on health related quality of life. The other domains of PCOS must also be evaluate as to how they will impact quality of life from a physical and psychological aspect and individualized strategies to improve quality of life in these

For this article there were no research questions, but the authors wanted to focus on the pathogenesis, diagnosis and treatment of PCOS. They found that polycystic ovary syndrome (PCOS) is common in women, with a10% prevalence in women of reproductive age. Polycystic ovary syndrome is defined as ovarian dysfunction with polycystic ovaries. It also includes androgen excess which is shown by testosterone levels being elevated. Increased levels of testosterone can be seen through excess body hair. Obesity is seen in many women with PCOS, this can lead to insulin resistance and Type II Diabetes. Genetics has an impact on polycystic ovary syndrome with 20-40% of people with PCOS having first-degree relatives with the syndrome.

Diet foods to eat sparingly, include: refined wheat baked goods, potatoes, beets, carrots, bananas, pineapple, watermelon and honey.

It is safe to consume red meat, as long it is no more than once a week. Garlic contains high level of antioxidants, which can boost one’s immune system. Whole grains such as corn, rice, corn, and quinoa provide abundant amounts of vitamins and minerals compared to refined grains. Toxins tend to reside in animal fat, especially fish, that can impair the immune defenses against abnormal cells in women with

There is one dream that every little girl has when growing up, that is becoming a mother; to love and watch her children grow. No one ever dreams of that not happening to them or being part of that group being label as infertile. It happens to millions of women living in the United States every day. Polycystic Ovary Syndrome is the most common endocrine disease that affects women of reproductive age, which is typically puberty to menopause. Polycystic Ovary Syndrome does not only affect a woman’s ovaries and chances of conceiving, but it affects the whole endocrine system in the body. It can cause Excess Androgen Production, Insulin Resistant, Obesity, Hirsute and Cardiovascular problems.

Role of leptin in PCOS. Leptin is a hormone secreted mainly from the adipose tissue, serum levels of which are influenced by obesity, insulin resistance and the levels of sex steroids (androgens and estrogens) and insulin. It is mainly involved in the regulation of body weight by decreasing appetite and increasing energy expenditure. Besides regulating the energy metabolism of the body, leptin has important actions on the reproductive system, which makes it an important link between the adipose tissue and hypothalamus– pituitary–gonadal (HPG) axis (2). Long-term hyperinsulinemia in humans, as is the case in PCOS patients, stimulates leptin secretion from adipose tissue (9). Significantly higher leptin (P = 0.0028), and insulin concentrations, insulin: glucose ratio (IGR), and a significant correlation between leptin and fasting insulin concentrations, IGR, WHR and LH have been reported in obese PCOS women than in normal-weight women with PCOS. There is a significant negative correlation between leptin and LH concentrations, independently of either BMI or IGR, suggesting a possible involvement of leptin in LH hypersecretion (10). Estrogens increase, whereas androgens suppress leptin production, suggesting sexual dimorphism in leptin levels (2).