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The Circulatory System

Decent Essays

The circulatory system consists of blood contained in a network of vessels called the vascular system. The above figure is a schematic of the human circulatory system, the heart pumps oxygenated blood from the left side to different parts of the body and returns back to the right side of the heart making a closed loop, this loop is called the systemic circuit. The blood from the heart is pumped into large muscular arteries from which it moves into smaller arteries and finally into the areole from which it is transported into the capillaries across which exchange of gases and nutrients through diffusion takes place
The compartmentalization technique to simulate multi organ function and response
The idea of compartmentalization is derived from the study of the cell organelles in an eukaryotic cell where each cell and its organelles are surrounded by a porous membrane that separated it from other components in its vicinity; the incorporation of this approach allows isolation of constraints and physical parameters to accurately define the micro habitat of these cells. Modern micro fabrication techniques can develop and control the characteristic features of the barrier separating different compartments. This results in a more accurate and relevant model of the human organ system where a group of cells forming tissues are contained in environments with well-defined parameters interact with each other to produce organ like function. These compartments de3veloped by micro

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