experiment is to determine the relative effectiveness of several anti-microbial substances on developing pathogens. (E. coli) BACKGROUND – E. coli is a food-borne bacterium that inhabits the bowels of warm blooded creatures such as humans and animals. If the individual is infected by E. coli, some symptoms can be “diarrhea, gas, abdominal cramping, fatigue, fever and vomiting.” (Pietrangelo”) If someone is infected with this bacterium, anti-biotics, which is explained by Oxford Dictionaries as “A medicine
of these systems are rare in natural products, but important in many studies for preparation of potentially, biologically active analogues. Indolizines are such type of systems, which contain ring junction nitrogen and are very rare in nature (Srikanth et al, 2011). Most indolizine compounds present interesting pharmacological effects (Singh and Mmatli, 2011) and several biologically active indolizines were reported to possess biological activities like; anti-inflammatory activities (Malone et al
of milk by reducing its overall microbial load. This method is the best because it does not add anything to the milk. A strong chemical for antimicrobial treatment is the preservation of meat or other food through preservatives. The presence of nitrates or high sodium content can cause foods to keep much longer and kill off addition microbes which attempt to form on the product, this is beneficial to other methods as you do not need to physically alter the product with heat or other physical changes
represent a major and as yet largely untapped source of great new pharmaceutical products. The most noteworthy medicinal effect of mushrooms and their metabolites that they fascinated the attention of the public in the modern years is their antitumour property. Many pharmaceutical ingredients with potent and unique properties were isolated from mushrooms and spread worldwide. Many of them are not strictly pharmaceutical products but represent the novel class of dietary supplements of approx. 10,000 known
Synthesis, Thermolysis, Photolysis and Animicrobial Evaluation of some Novel Semicarbazones and Thiosemicarbazones Derived from 3-Methyl-2-benzothiazolinone Hydrazone. Hisham Abdallah A. Yosef * and Nabila M. Ibrahim Department of Organometallic and Organometalloid Chemistry, National Research Centre, El-Behouth Street, P.O. 12622, Dokki, Giza, Egypt. Abstract: Reaction of 3-Methyl-2-benzithiazolinone hydrazone (1) with some seleceted isocyanate and isothiocyanate reagents 2a−j gave the respective
Over the past few decades, herbal drugs have become more popular among the people in the world. A regular and widespread use of herbs throughout the world has increased serious concerns over their quality, safety and efficacy. Further about 80% of world population depends on herbal preparations for primary healthcare needs. In many developed countries, 70 to 80 per cent of the populations have used some form of complementary or alternative medicines composed primarily of herbal medicines (Firenzuoli
- Introduction: Antibiotics are an expansive class of antimicrobial drugs, also referred to as antibacterial agents, which are mainly used to overcome bacterial infections by either eliminating or inhibiting the growth of these infectious agents (Demain and Fang, 2000). Antibiotics, alongside vaccination, played a key role in revolutionizing medicine during the 20th century, as well as coming close to eradicating diseases such as tuberculosis (Berdy, 2005). Moreover, these antimicrobial drugs are
1. Introduction 1.1 Introduction to HPLC 1.2 Types of HPLC techniques 1.3 HPLC instrumental parameters 1.4 Significance of Analytical Method Validation 1.5 ICH Guidlines Pharmaceutical analysis: It is the interdisciplinary subject and it is derived from various branches of sciences like chemistry,physics, microbiology, nuclear science and electronics which deals with analysis
shape, color and other markings necessary to identify the product. Tablets must retain all these functional attributes which include drug stability and efficacy.(Remington.,1998). Advantages of tablets Large scale manufacturing is feasible in comparison to other dosage forms. Therefore, economy can be achieved. Accuracy of dose is maintained since tablet is a solid unit dosage form. Longer expiry period and minimum microbial spillage owing to lower moisture content. As tablet is