hardy

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Population Genetics / Hardy-Weinberg Problems

Directions: Work out the following problems on a separate piece of paper. Show ALL work and circle your answers.

1) If the frequency of a recessive allele is 30% in a population of 100 people, how many would you predict would be carriers of this allele, but would not express the recessive phenotype? q= 0.30 p= 0.70

Carriers = 2pq = 2(.3)(.7) = .42
#= (.42)(100) = 42 individuals

2) From a sample of 278 American Indians, the following MN blood types were obtained: MM = 78, MN = 139, NN = 61. Calculate the allele frequency of M and N.
M= 0.53
N= 0.47

MM = 78/278 = 0.281 = p2 p = 0.530 = 53%
MN = 139/278 = 0.50 = 2pq q = 0.468 = 46.8%
NN = 61/139 = 0.219 = q2

3)
Complete the following chart based on this information.
The frequency of the (H) allele =
0.7
The total number of homozygous nonallergic Pago Fuagens =
2450
(5000 x 0.49)
The frequency of the (h) allele =
0.3
The total number of Pago Fuagans that are carriers of the (g) allele and phenotypically normal =
2100
(5000 x 0.42)
The total number of (h) alleles on Pago Fuago =
3000
(10,000 x 0.3)
The total number of Pago Fuagens that suffer from this