. At pH 4.4, there exists in solution equal amounts of the neutral and charged atropine molecules b. Atropine is a non-electrolyte drug c. Atropine releases its proton at pH 4.4 d. Atropine is most soluble at pH values higher than 4.4 e. If atropine is to be prepared in transdermal patches, the solution in the patch reservoir should have a pH

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a. At pH 4.4, there exists in solution equal amounts of the neutral and charged atropine molecules b. Atropine is a non-electrolyte drug c. Atropine releases its proton at pH 4.4 d. Atropine is most soluble at pH values higher than 4.4 e. If atropine is to be prepared in transdermal patches, the solution in the patch reservoir should have a pH less than 4.4 for maximum absorption.
Atropine (Structure is shown below) is an
anticholinergic drug used to treat certain
types of nerve agents and pesticide
poisonings. If the pKb of atropine is 4.4,
which of the following statements about
atropine must be true?
'N.
Atropine
Transcribed Image Text:Atropine (Structure is shown below) is an anticholinergic drug used to treat certain types of nerve agents and pesticide poisonings. If the pKb of atropine is 4.4, which of the following statements about atropine must be true? 'N. Atropine
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