Answered: Draw a titration curve for the…

Draw a titration curve for the tetrapeptide Trp-Asp-Lys-Gly. Label all pK,s, the pl and the net molecular charges at pH 1 and pH 14 on the graph with their values.

Chemistry: Principles and Reactions

8th Edition

ISBN:9781305079373

Author:William L. Masterton, Cecile N. Hurley

Publisher:William L. Masterton, Cecile N. Hurley

Chapter23: Organic Polymers, Natural And Synthetic

Section: Chapter Questions

Problem 29QAP: For alanine, Ka1=5.1105,Ka2=1.81010 . Calculate the ratios [Z]/[C+] and [Z]/[A+] at pH (a) 2.00. (b)...

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Question

4) Draw a titration curve for the tetrapeptide Trp-Asp-Lys-Gly. Label all pK,s, the pl and the net
molecular charges at pH 1 and pH 14 on the graph with their values.

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Given tetrapeptide:

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Structural representation

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Determination of pI

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Determination of pI (continued)

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Determination of pI (continued)

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Determining charge at pH 1

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Determining charge at pH 14

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Titration curve

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