Introduction to General, Organic and Biochemistry
11th Edition
ISBN:9781285869759
Author:Frederick A. Bettelheim, William H. Brown, Mary K. Campbell, Shawn O. Farrell, Omar Torres
Publisher:Frederick A. Bettelheim, William H. Brown, Mary K. Campbell, Shawn O. Farrell, Omar Torres
Chapter20: Carbohydrates
Section: Chapter Questions
Problem 20.14P
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Question
Several steps in the synthesis of optically active duloxetine, an
antidepressant sold under the trade name Cymbalta, are shown. Identify
the structure of intermediates A–C and the final product duloxetine,
including stereochemistry, in this reaction sequence.
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