1. Predict the membrane orientation of a protein that is synthesized with the following features:(Draw the protein on the membrane and indicate where the N-terminus and C-terminus are).ERSSSTOPStartCcvtosolER lumenWhere would we find the N and C termini as this moves through the ER and Golgi?If this were a membrane protein, where we we find the N and C termini?

The insertion of membrane proteins in their right orientation is decided by multiple sequences that…

1. Predict the membrane orientation of a protein that is synthesized with the following features: (Draw the protein on the membrane and indicate where the N-terminus and C-terminus are). N ERSS STOP Start C cvtosol ER lumen Where would we find the N and C termini as this moves through the ER and Golgi? If this were a membrane protein, where we we find the N and C termini?

1. Predict the membrane orientation of a protein that is synthesized with the following features: (Draw the protein on the membrane and indicate where the N-terminus and C-terminus are). N ERSS STOP Start C cvtosol ER lumen Where would we find the N and C termini as this moves through the ER and Golgi? If this were a membrane protein, where we we find the N and C termini?

Biology 2e

2nd Edition

ISBN:9781947172517

Author:Matthew Douglas, Jung Choi, Mary Ann Clark

Publisher:Matthew Douglas, Jung Choi, Mary Ann Clark

Chapter5: Structure And Function Of Plasma Membranes

Section: Chapter Questions

Problem 6RQ: What is the primary function of carbohydrates attached to the exterior of cell membranes?...

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Similar questions

1. Working as an engineer in the R&D section of a biotech industry, you are asked to select a membrane to concentrate a solution containing a protein with a molecular weight of 200 kDa; Fortunately, it has three types of membrane in the cellar: one for MF, one for UF and one for RO. Which one would you choose to perform the required service? Could you establish some characteristics of the chosen membrane?
1. Explain in detail how amino acids can be transported across the plasma membrane 2. By using the concept of endomembrane system, explain how plasma membrane involves in the protein synthesis of a cell. 3. With suitable examples, compare the structural and functional differences between a fibrous and globular protein. 4. A person suffers from a skin condition and loss of muscle. A doctor suspects the patient has protein deficiency. Justify why the doctor thinks so.
2 For each protein, identify the following: If the protein is an integral, peripheral, or amphitropic membrane protein. Explain. If the protein monotopic, bitopic, or polytopic. Explain Proteins: 5EH4, 7CNE, 6GIQ, 1GYG
5.5. Protein modifications occurring in the Golgi apparatus include : BIOCHEMISTRY_advanced a) removal of sialic acid. b) BiP-mediated protein folding. c) removal of the signal peptide. d) ubiquitination. e) modification of high-mannose and complex N-linked oligosaccharides.
1. Researchers have discovered a new membrane protein that has three transmembrane domain αhelixes that span the lipid bilayer. a. If the lipid bilayer is 30 Å thick, what is the smallest number of amino acid residues that can be in each α-helixes for them to be long enough to span the bilayer? b. If one of the three α-helixes is titled at a 32° angle relative to an axis perpendicular to the surface of the lipid bilayer, what is the smaller number of amino acid helixes required for that helix to still span the lipid bilayer? c. How many hydrogen bonding interactions would there be in the smallest possible tilted transmembrane α-helix? d. If the tilted α-helix was a 310 helix instead how many amino acid residues would be required to span the lipid bilayer? How many amino acid residues would be required if it was a π-helix?
1) Identify THREE macromolecules that are components of the plasma membrane in a eukaryotic cell and discuss the structure and function of each.
1)You add a drug to cells that can pass through hydrophilic or hydrobic environments (e.g., membranes & cytosol). The drug specifically prevents the binding of KDEL (ER retention signal) to any other molecules. In the short term, what would happen to the synthesis and localization of translocon proteins? a. New complete translocon proteins would be made, but they would end up in the golgi apparatus. b. New complete translocon proteins would be made, but they would end up at the plasma membrane c. No new intact translocon proteins would be synthesized d. New complete translocon proteins would be made, but they would be secreted e. New complete translocon proteins would be made and localized normally
Imagine protein X, destined to span theplasma membrane. Assume that the mRNA carrying the geneticmessage for protein X has already been translated by ribosomesin a cell culture. If you fractionate the cells (see Figure 6.4), inwhich fraction would you find protein X? Explain by describingits transit through the cell.
A scientist compares the plasma membrane composition of an animal from the Mediterranean coast with one from the Mojave Desert. Which hypothesis is most likely to be correct? The cells from the Mediterranean coast animal will have more fluid plasma membranes The cells from the Mojave Desert animal will have a higher cholesterol concentration in the plasma membranes The cells’ plasma membranes will be indistinguishable The cells from the Mediterranean coast animal will have a higher glycoprotein content, while the cells from the Mojave Desert animal will have a higher lipoprotein content.
Which of the following structures is not used in eukaryotic protein manufacture and sectretion? a. ribosome b. lysosome c. rough ER d. secretory vesicle e. Golgi complex
What is the primary function of carbohydrates attached to the exterior of cell membranes? identification of the cell flexibility of the membrane strengthening the membrane channels through membrane
The freeze-fracture technique demonstrated: a. that the plasma membrane is a bilayer with individual proteins suspended in it. b. that the plasma membrane is fluid. c. that the arrangement of membrane lipids and proteins is symmetric. d. that proteins are bound to the cytoplasmic side but not embedded in the lipid bilayer. e. the direction of movement of solutes through the membrane.