11, Gene mutation and DNA repair: Outline Mutations How mutations happen: spontaneous How mutations happen: induced Ames test DNA repair Double-strand breaks and recombination Transposable elements

Q: Which of the following is considered to be a spontaneous source of mutations that impact the genome?…

A: Any Change in the genetic material, which is not caused by recombination, that leads to altered…

Q: You graduate and land a job in a medical genetics laboratory.  A particular family has been…

A:

Q: Used as markers for identification purposes, ___________ are locations on the chromosome that…

A: The size of the human genome is largely due to the presence of 3.2 billion base pairs in DNA. The…

Q: Which type of mutation involves only one base pair? a. insertion b. deletion c. inversion d.…

A: A mutation occurs when DNA molecules are copied or replicated, resulting in DNA variants that can be…

Q: Explain the connection between defects in DNA repair systemsand the inherited human disease…

A: Genetic disorder It is also called as inherited disorder and is caused due to, Chromosomal…

Q: In the procedure for isolating DNA, what is the purpose of adding washing-up liquid? 1.Washing up…

A: Extraction of DNA is an important and delicate procedure from the nucleus of the cells. The ability…

Q: Mutated DNA Template Strand #1: 3’-T A C T G T C T G A C G A T C-5’ Amino acid sequence of peptide:…

A: Point mutation

Q: Which of the following is FALSE about DNA methylation? O a. the base to be methylated is found in…

A: The CpG sites or CG sites are regions of DNA where a cytosine nucleotide is followed by the guanine…

Q: Which of the following can only arise as a spontaneous mutation? Group of answer choices Gamma rays…

A: A mutation is a change in the sequence of the DNA. It affects the codons of the DNA or mRNA, which…

Q: Which of the following is considered to be a spontaneous source of mutations that impa the genome? O…

A: The genome is the finished arrangement of hereditary information in a organic entity. It gives all…

Q: Which of the following is not a factor that increases mutations?   A. replication errors   B.…

A: A mutation is a variation that happens in the DNA chain, due to errors during the DNA is duplicated…

Q: Mutations are the original source of genetic variation. How can mutations accumulate in DNA, given…

A: A mutation is a change in a DNA sequence. Mutations can result from DNA copying mistakes made during…

Q: How does E. coli determine which nucleotide to "fix" in a base mismatch? The appropriate DNA repair…

A: MutS recruits MutL and two MutH proteins to the mismatch.

Q: If a person is lacking a gene that codes for a protein involved in nucleotide excision repair, then…

A: DNA can experience a variety of chemical reactions, as in any other molecule. However, since DNA is…

Q: Compare and contrast the action of DNA damaging agents that lead to: 1. Point mutations . 2.…

A: 1. Point mutation... Point mutation is the single nucleotide mutation in DNA. In this mutation…

Q: An induced mutation occurs when a non-disjunction event happens during mitosis. a non-disjunction…

A: DNA( deoxyribonucleic acid) is the double-stranded molecule that is the genetic material in most…

Q: 3 2 If there are no mutations during this process, which of the following pairs of strands will have…

A: DNA replication is the process by which a double stranded DNA first splits up into two separate…

Q: Which one is correct about telomeres? Choose at least one correct answer TTAGGG sequence is…

A: The distinctive structures that are found at the ends of our chromosomes and  consist of the…

Q: Which of the following is involved in the repair of cyclobutane pyrimidine dimers?   DNA pol I…

A: The process by which a cell uses a series of special enzymes to repair mutation (changes ) in DNA…

Q: Why are mutations more likely to occur in repeated DNA sequences? a. These bases are unstable b.…

A: Repetitive DNA sequence Repetitive DNA refers to the stretches of DNA that repeat throughout the…

Q: what type of mutation can be avoided when doing the following: 1. Eating healthy foods 2. avoiding…

A: A mutation is an alteration in a DNA sequence caused due to various factors such as exposure to…

Q: ____________ proliferate by cutting and pasting the original copy to another part of the genome,…

A: Genetic material is nothing but the sequence of nucleic acids which is called as DNA. It contains…

Q: Which of the following are the correct types of chromosomal mutation as shown from Figure 1.4? *…

A: Correct option is B i.e.  Inversion Insertion Deletion Translocation

Q: The most common source of DNA mutation is _____; however, these mistakes are typically corrected.​…

A: To understand the structure of nucleic acid, it is necessary to first understand the structure of…

Q: One of the mechanisms that leads to the DNA mutations is a process known as DNA polymerase slippage…

A: DNA slippage is a type of DNA strand misfiring mechanism that occurs in the repeated nitrogenous…

Q: What affect one or just a few base pairs in the DNA and thus alter only one gene at a time?

A: DNA (deoxyribonucleic acid) is a macromolecule that functions as the genetic material. It contains…

Q: When dna is methylated, which of the following is an associated characteristed? (select the best…

A: DNA is the geentic material which is controlled by various means for controlling it's gene…

Q: Define the following terms: a. single nucleotide polymorphism b. nonsense mutation c. indel d.…

A: Answer- Mutations are the changes in the DNA sequence that happen due to the exposure of mutagens…

Q: Point mutations affect. can be classified by Answer 1 Answer 2 Answer 8 in which nucleotide base…

A: Mutations are the result of a change in the genetic code of an organism. It can occur DNA or RNA or…

Q: Generate a concept map that includes all the specifics below: Classification based on: 1. their…

A: A concept map, also known as a conceptual diagram, is a graphic that shows possible connections…

Q: When does DNA replication occur in the cell cycle? Replicate this strand of DNA: ATTCGC TAG…

A: The cell cycle is a sequence of events before cell division occurs, it prepares cells for division.…

Q: Which of the following is NOT a function of DNA polymerase III? Group of answer choices Exonuclease…

A: The main activity of DNA polymerase 3 is to add nucleotides to the short RNA primers. This is the…

Q: Which of the following is FALSE about "classic" transposons and retrotransposons? Ac is an…

A: Barbara McClintock discovered two classes of controlling elements in maize plant known as…

Q: Which of the following statements is/are TRUE about DNA repair?   Question 24 options:     Ensure…

A: DNA repair It is a collection of processes by which a cell identifies and corrects damage to the…

Q: The first 15 bases of the original informational strand of DNA (which continues after what is shown)…

A: Mutation is the change in DNA sequence caused due to various factors. Mutations take place during…

Q: Huntington’s disease is a hereditary central nervous system disorder characterized by tandem repeats…

A: Several genetic disorders are related to polymorphic sequences. It is studied under the domain of…

Q: List two specific causes of DNA mutations.  - environmental agents like ultraviolet light or…

A: A mutation is a change in the sequence of DNA which can result from DNA copying mistakes made during…

Q: ______________ is a kind of spontaneous mutation that results from a short-term, reversible…

A: Spontaneous mutations that is changes in the DNA sequence arise from a variety of sources, including…

Q: Which of the following is a transition mutation? OC--> G OC --> T OC --> A

A: Transition is a point mutation where replacement of base pair occurs.

Q: What will be the results of chemically modifying one nucleotide baseof a gene? What role is played…

A: A permanent change in the DNA’s base sequence is termed as mutation. Any alteration in DNA may cause…

Q: Describe 6 different types of mutations that can occur at the chromosomal and nucleotide levels.…

A: Mutation is a permanent change in the nucleotide sequence of an organism's genome, virus,…

Q: Mutations can be caused by which process?   faulty DNA repair   nondisjunction   base sequence…

A: Mutation is defined as any heritable change in the genetic makeup of an individual. It is a sudden…

Q: DNA before and after mutation. Which of on. Which of the following are CORRECT about the types of…

A: Mutation is the change in the nucleotide of the DNA sequence which ultimately affects the Amino acid…

Q: Zinc finger nuclease is a Gene editing tool: Question 13 options: which uses a site-specific…

A: These are multiple choice questions.

Q: What are the steps in DNA Methylation? Take note, that important enzymes and chemicals are needed in…

A: We must provide an explanation of the steps involved in DNA methylation in accordance with the…

Q: DNA to Protein 1. Describe the mutation that created the Hbs allele: type of mutation, location of…

A: sickle cell anaemia is an autosomal linked recessive trait that can be transmitted from parents to…

Q: The mutation for drug resistance in Mycobacterium tuberculosis, the bacteria that causes the disease…

A: M. tuberculosis is a bacterial species which is responsible for causing tuberculosis of all kinds…

Q: Which of the following is not an example of a spontaneousmutation?a. A mutation caused by an error…

A: The mutation is a permanent alteration, a structural change in the ribonucleic acid (RNA) or…

Mitochondrial Mutations

A mitochondrion is a cellular organelle that serves as the site for cellular respiration and energy production (ATP or Adenosine Triphosphate). It is a double-membrane-bound organelle and is only present in eukaryotic cells.