Question
Asked Nov 4, 2019
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How are trisomies and monosomies related to deletions and duplications respectively?

What is the significance of the following concepts in the image attached below and how are they linked (big picture)

 

11, Gene mutation and DNA repair: Outline
Mutations
How mutations happen: spontaneous
How mutations happen: induced
Ames test
DNA repair
Double-strand breaks and recombination
Transposable elements
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11, Gene mutation and DNA repair: Outline Mutations How mutations happen: spontaneous How mutations happen: induced Ames test DNA repair Double-strand breaks and recombination Transposable elements

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Expert Answer

Step 1

Trisomy is the condition in which a diploid organism will have one duplicate copy of one of its chromosomes or segments of a chromosome. This occurs due to the error during the meiosis. At the end of meiosis gamete should be haploid, but sometimes there will be no separation of chromosomes. So the resulting embryo will be an aneuploidy embryo. Example of this condition is Down syndrome.

 

Step 2

Monosomy is the state where there will be only a single copy of the chromosome instead of two copies. This occurs as a result of the deletion of part of the chromosome during cell division. This will result in abnorm...

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