Homework Help is Here – Start Your Trial Now!
Engineering
Chemical Engineering
11.16. Proteins in aqueous solution fold to unique three-dimensional structures at ambient conditions. However, they also have a first-order-like transition to a state of less-structured, floppy configurations that can be accomplished in a number of ways. The most common is by increasing T past the folding tempera- ture at ambient pressure. They can also be unfolded by extreme compression, cooling, and expansion into the negative-pressure regime, at least in theory Figure 11.8 gives a schematic of the "phase" behavior and these four mechanisms of unfolding. (a) For each mechanism, indicate the signs of the volume and entropy changes associated with the folded-to-unfolded transition, namely AV Vunfolded Vfolded and AS Sunfolded Sfolded Figure 11.8. Proteins can exist in folded and unfolded states depending on the pressure and temperature. The gray line denotes the boundary between the two, called the folding curve. The indicates ambient conditions. compression folded heat cold -T unfolded expansion/stretching (b) Explain why the cooling and stretching mechanisms might be difficult or impossible to realize in an experiment. Hint: what would happen if the solution contained no proteins?

11.16. Proteins in aqueous solution fold to unique three-dimensional structures at ambient conditions. However, they also have a first-order-like transition to a state of less-structured, floppy configurations that can be accomplished in a number of ways. The most common is by increasing T past the folding tempera- ture at ambient pressure. They can also be unfolded by extreme compression, cooling, and expansion into the negative-pressure regime, at least in theory Figure 11.8 gives a schematic of the "phase" behavior and these four mechanisms of unfolding. (a) For each mechanism, indicate the signs of the volume and entropy changes associated with the folded-to-unfolded transition, namely AV Vunfolded Vfolded and AS Sunfolded Sfolded Figure 11.8. Proteins can exist in folded and unfolded states depending on the pressure and temperature. The gray line denotes the boundary between the two, called the folding curve. The indicates ambient conditions. compression folded heat cold -T unfolded expansion/stretching (b) Explain why the cooling and stretching mechanisms might be difficult or impossible to realize in an experiment. Hint: what would happen if the solution contained no proteins?

Introduction to Chemical Engineering Thermodynamics
Introduction to Chemical Engineering Thermodynamics
8th Edition
ISBN:9781259696527
Author:J.M. Smith Termodinamica en ingenieria quimica, Hendrick C Van Ness, Michael Abbott, Mark Swihart
Publisher:J.M. Smith Termodinamica en ingenieria quimica, Hendrick C Van Ness, Michael Abbott, Mark Swihart
Chapter1: Introduction
Section: Chapter Questions
Problem 1.1P
See similar textbooks
icon
Related questions
Question

This problem is (11.16) from a book  "Thermodynamics and Statistical Mechanics An Integrated Approach by M. Scott Shell"

11.16. Proteins in aqueous solution fold to unique three-dimensional structures at ambient conditions. However, they also have a first-order-like transition to a state of less-structured, floppy configurations that can be accomplished in a number of ways. The most common is by increasing T past the folding tempera- ture at ambient pressure. They can also be unfolded by extreme compression, cooling, and expansion into the negative-pressure regime, at least in theory Figure 11.8 gives a schematic of the "phase" behavior and these four mechanisms of unfolding. (a) For each mechanism, indicate the signs of the volume and entropy changes associated with the folded-to-unfolded transition, namely AV Vunfolded Vfolded and AS Sunfolded Sfolded Figure 11.8. Proteins can exist in folded and unfolded states depending on the pressure and temperature. The gray line denotes the boundary between the two, called the folding curve. The indicates ambient conditions. compression folded heat cold -T unfolded expansion/stretching
Transcribed Image Text:11.16. Proteins in aqueous solution fold to unique three-dimensional structures at ambient conditions. However, they also have a first-order-like transition to a state of less-structured, floppy configurations that can be accomplished in a number of ways. The most common is by increasing T past the folding tempera- ture at ambient pressure. They can also be unfolded by extreme compression, cooling, and expansion into the negative-pressure regime, at least in theory Figure 11.8 gives a schematic of the "phase" behavior and these four mechanisms of unfolding. (a) For each mechanism, indicate the signs of the volume and entropy changes associated with the folded-to-unfolded transition, namely AV Vunfolded Vfolded and AS Sunfolded Sfolded Figure 11.8. Proteins can exist in folded and unfolded states depending on the pressure and temperature. The gray line denotes the boundary between the two, called the folding curve. The indicates ambient conditions. compression folded heat cold -T unfolded expansion/stretching
(b) Explain why the cooling and stretching mechanisms might be difficult or impossible to realize in an experiment. Hint: what would happen if the solution contained no proteins?
Transcribed Image Text:(b) Explain why the cooling and stretching mechanisms might be difficult or impossible to realize in an experiment. Hint: what would happen if the solution contained no proteins?
Expert Solution
trending now

Trending now

This is a popular solution!

steps

Step by step

Solved in 4 steps with 2 images

SEE SOLUTIONCheck out a sample Q&A here
Blurred answer
Knowledge Booster
Enzymatic and non Enzymatic reactions
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, chemical-engineering and related others by exploring similar questions and additional content below.
Recommended textbooks for you
Introduction to Chemical Engineering Thermodynami…
Introduction to Chemical Engineering Thermodynami…
Chemical Engineering
ISBN:
9781259696527
Author:
J.M. Smith Termodinamica en ingenieria quimica, Hendrick C Van Ness, Michael Abbott, Mark Swihart
Publisher:
McGraw-Hill Education
Elementary Principles of Chemical Processes, Bind…
Elementary Principles of Chemical Processes, Bind…
Chemical Engineering
ISBN:
9781118431221
Author:
Richard M. Felder, Ronald W. Rousseau, Lisa G. Bullard
Publisher:
WILEY
Elements of Chemical Reaction Engineering (5th Ed…
Elements of Chemical Reaction Engineering (5th Ed…
Chemical Engineering
ISBN:
9780133887518
Author:
H. Scott Fogler
Publisher:
Prentice Hall
Process Dynamics and Control, 4e
Process Dynamics and Control, 4e
Chemical Engineering
ISBN:
9781119285915
Author:
Seborg
Publisher:
WILEY
Industrial Plastics: Theory and Applications
Industrial Plastics: Theory and Applications
Chemical Engineering
ISBN:
9781285061238
Author:
Lokensgard, Erik
Publisher:
Delmar Cengage Learning
Unit Operations of Chemical Engineering
Unit Operations of Chemical Engineering
Chemical Engineering
ISBN:
9780072848236
Author:
Warren McCabe, Julian C. Smith, Peter Harriott
Publisher:
McGraw-Hill Companies, The
SEE MORE TEXTBOOKS