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- 1.Enumerate the enzymes of the alpha ketoglutarate dehydrogenase complex and write its mechanism of action1. Discuss the synthesis and utilization of ketone bodies. 2. Describe adequately the beta-oxidation of fatty acids. 3. What are the different pathways of glucose metabolism?1. Discuss fully the synthesis of triacylglycerol in the adipose tissue, muscles, intestines and liver. 2. Describe adequately the beta-oxidation of fatty acids. 3. Discuss the synthesis and utilization of ketone bodies.
- 1.Why do you think glutathione occurs in a concentration as high as glucose? 2.Explain why glutathione must be transported from cytosol to mitochondria. 3.Explain why glutathione can confer therapeutic benefit when taken orally.Radiolabeling with 14C-Glutamate Describe the labeling pattern that would result from the introduction into the TCA cycle of glutamate labeled at Cy with 14C.3. How is acetyl coA carboxylase being regulated?
- 1.a. Given what you know about glycolysis and gluconeogenesis, does it make sense that insulin activates PDH phosphatase? Why? b.How do vitamins increase to the breadth of chemical reactions available within a biological system?1. What is the difference between ketogenic and glucagenic amino acids? 2. What is the difference between transamination and oxidative deamination?Malonyl-CoA synthesized by the action of acetyl-CoA carboxylase II is primarily used:a. To synthesize fatty acidsb. To inhibit fatty acid oxidationc. Both a and bd. Neither a nor b
- What is the likely substrate of α ketoglutatrate dehydrogenase? A) water B) alpha ketoglutatrate C) protons D) ketoacids1. Malonyl Co A: a. Produced during the elongation of fatty acid degradation ċ .b. A key intermediate in fatty acid synthesis c. Produced as a result of decarboxylation of acetyl Co A ċ d. A key intermediate in fatty acid degradation37-Which of the following would be the best way to increase your intake of very long omega-3 fatty acids? a.Eat more fish. b.Eat more plants. c.Eat more seed oils. d.Take supplements.