19. Tumor suppressor genes/Oncogenes: Describe how viruses can lead to cancer formation in animal hosts. In your response, describe the terms tumor suppressor gene, proto-oncogene, and oncogene. Use HPV as an example of how different types of tumors may develop and why it may be advantageous to a virus to interfere with proto- oncogenes or tumor suppressor genes.

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Asked Oct 18, 2019

19. Tumor suppressor genes/Oncogenes: Describe how viruses can lead to cancer formation in animal hosts. In your response, describe the terms tumor suppressor gene, proto-oncogene, and oncogene. Use HPV as an example of how different types of tumors may develop and why it may be advantageous to a virus to interfere with proto- oncogenes or tumor suppressor genes.

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Expert Answer

Step 1

A microscopic infective agent that consists of nucleic acid (DNA/RNA) enclosed in a protein coat is referred to as the virus. The viruses could not survive individually and they are capable of multiplying only in a living host cell by using the host’s metabolism.

Step 2

When the viruses infect the animal host, they incorporate their genetic material (DNA) into the DNA of the host cell. Then it affects the healthy genetic makeup of the host cell and potentially leading them to turn into cancer.

Step 3

Tumor-suppressor gene: 

Tumor-suppressor gene is a type of gene that synthesizes a protein called tumor-suppressor protein. This protein plays an essential role in controlling the growth of the cell. The tumor-suppressor gene is involved in regulating the cell during its division and replication. Mutations or alterations in this gene might lead to cancer.

Proto-oncogene: 

The proto-oncogenes are the normal cellular genes that are involved in cel...

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