7) The protein VEGF plays an important role in stimulating the formation of new blood vessels. In some circumstances, cancer cells will produce too much VEGF. The drug PTC299 is currently being researched as a potential anti-cancer drug. It works by binding to VEGF MRNA, stopping this mRNA from being read by the ribosome. Therefore, not as much VEGF protein is produced. (National Cancer Institute. nd. NCI Drug Dictionary. Retrieved from: https://www.cancer.gov/publications/dictionaries/cancer-drug/def/vegf-inhibitor-ptc299) a) If approved, what kind of cancer treatment would it be considered (radiotherapy, gene therapy- anti-angiogenesis)? b) Briefly explain why you think PTC299 fits the kind of cancer treatment you indicated in a). Use information from the text to support your answer. c) Would PTC299 be considered a traditional or a targeted therapy?

Biology: The Dynamic Science (MindTap Course List)
4th Edition
ISBN:9781305389892
Author:Peter J. Russell, Paul E. Hertz, Beverly McMillan
Publisher:Peter J. Russell, Paul E. Hertz, Beverly McMillan
Chapter16: Regulation Of Gene Expression
Section: Chapter Questions
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7) The protein VEGF plays an important role in stimulating the formation of new blood vessels.
In some circumstances, cancer cells will produce too much VEGF.
The drug PTC299 is currently being researched as a potential anti-cancer drug. It works by
binding to VEGF mRNA, stopping this mRNA from being read by the ribosome. Therefore, not
as much VEGF protein is produced. (National Cancer Institute. nd. NCI Drug Dictionary. Retrieved
from: https://www.cancer.gov/publications/dictionaries/cancer-drug/def/vegf-inhibitor-ptc299)
a) If approved, what kind of cancer treatment would it be considered (radiotherapy, gene therapy.
anti-angiogenesis)?
b) Briefly explain why you think PTC299 fits the kind of cancer treatment you indicated in a).
Use information from the text to support your answer.
c) Would PTC299 be considered a traditional or a targeted therapy?
Transcribed Image Text:7) The protein VEGF plays an important role in stimulating the formation of new blood vessels. In some circumstances, cancer cells will produce too much VEGF. The drug PTC299 is currently being researched as a potential anti-cancer drug. It works by binding to VEGF mRNA, stopping this mRNA from being read by the ribosome. Therefore, not as much VEGF protein is produced. (National Cancer Institute. nd. NCI Drug Dictionary. Retrieved from: https://www.cancer.gov/publications/dictionaries/cancer-drug/def/vegf-inhibitor-ptc299) a) If approved, what kind of cancer treatment would it be considered (radiotherapy, gene therapy. anti-angiogenesis)? b) Briefly explain why you think PTC299 fits the kind of cancer treatment you indicated in a). Use information from the text to support your answer. c) Would PTC299 be considered a traditional or a targeted therapy?
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