2. Amide are considered to be a bad leaving group because of what electronic effect a. +I b. -I с. + М d. - M

Q: 1. Give a synthetic route (hint: protecting group). OH

A:

Q: Show the stepwise mechanism for the reaction between methanoyl bromide and  methyl amine.  Use…

A:

Q: Scheme 2: Synthesis of a common antihistamine from benzaldehyde. Mg, ether 1. Ether 2. 1M HCI HBr…

A: Diphenhydramine is an antihistamine. Synthesis of antihistamine from benzaldehyde:

Q: B) Cyclopent-2-en-one to 3-oxocyclopentane carboxylic acid C) Cyclopentane to N,N-diethyl…

A:

Q: What is the difference, in terms of chemical components, between Benedict's and Fehling's reagent?…

A: Interpretation: We have to tell the difference between Benedict's reagent and Fehling's reagent.

Q: Explain why the reaction of an alkyl halide with ammonia gives a low yield of primary amine.

A: Since after the first step of the reaction, we get a C attached to the N in the molecule as shown in…

Q: Which is the stronger base: N-methylaniline (C6H5NHCH3) or benzylamine (C6H5CH2NH2). Explain your…

A: The stronger base out of N-methylaniline and benzylamine has to be determined on the basis of…

Q: Fill in the blanks: B A OH Compound A can be converted to cyclobutanol using the reagent Compound B…

A:

Q: Why is anisole nitrated more rapidly than thioanisole under the same conditions?

A: Nitration is an electrophilic substitution reaction in which nitronium ion attacks on the benzene…

Q: 27(c) Most basic nitrogen A or B? (Hint: The lone pairs on the two play different roles in the…

A: The basicity of the nitrogen depends on the availability of electron density on the nitrogen atom in…

Q: a) A specific example of the Curtius rearrangement of an acyl azide to an isocyanate. b) The anionic…

A: We have find out solution. Note -As per our company guidelines we are supposed to answer only first…

Q: How is an amide converted to an anhydride? Water with strong acid → PCl5 → Carboxylic Acid PCl5 →…

A:

Q: Chlorine is a(n) (CIRCLE one) ortho-para/meta director. Explain your answer.

A: Please find your solution below : Chlorine has dual nature when it is attached to benzene ring. It…

Q: a) What would be the electron pushing mechanism for transformation of Meldrum's acid into A? b)…

A: Hello. Since your question has multiple parts, we will solve first question for you. If you want…

Q: Chemistry   Draw the product formed when phenylacetaldehyde (C6H5CH2CHO) is treated with reach…

A: Detail mechanistic pathway is given below to find out the product in every case

Q: A retrosynthetic analysis of 1 was undertaken suggesting a forward synthesis starting from compounds…

A: Epoxides can be converted to aminoalcohols by the reaction of epoxide directly with ammonia or first…

Q: Explain which position in indole will be susceptible to SEAr reactions

A: Indole has C3 position that is susceptible to SEAr, aromatic electrophilic substitution reaction.

Q: What would be the product (s) of treating a mixture of 1.0 mmol of 2-methylpyridine and 1.0 mmol of…

A:

Q: Why is alkoxide (RO-) a stronger base than Chloride? Why are alcohols typically poor electrophiles?

A: 1. alkoxide ions are better proton acceptors as compared to hydroxide ion which makes them stronger…

Q: Explain

A: Since you have asked multiple question, we will solve the first question for you.If you want any…

Q: (a) How will you convert the following :(i) Propanone to Propan-2-ol                (ii) Ethanal to…

A: Oxidation It is the process of gaining of oxygen Different oxidizing agents are; alkaline KMnO4, Br2…

Q: NABH4 CH3CH2OH

A: In this question, we have to find out the correct answer of given problem by the help of the…

Q: Asssign R and s configuration to naproxen. What are the percentage of R and S in the mixture

A:

Q: Briefly explain why OtBu- sometimes favored over hydroxide as an elimination reagent?

A:

Q: Rank the following compounds in order of increasing basicity: I. p-nitroaniline II.…

A:

Q: To prepare butanoic acid from 1-propanol, which sequence of reagent(s) is/are best employed?   a)…

A: Scheme 1: Step 1 : propanol is converted into bromo propane using PBr3. Step 2: Bromo propane is…

Q: c) Scheme 1 shows the retrosynthetic analysis of compound M to the precursors via Functional Group…

A: The given transformation can be done by following reagents  A= 1)Mg/Ether, 2) CO2 3) H3O+ B= 1)…

Q: Why is an alkylamine more basic than ammononia?

A: Because of electron delivering nature, the alkyl gathering (R) pushes electrons towards nitrogen in…

Q: d. Aflatoxin B, hemiacetal racemizes readily in basic solution. OCH3 O: OH Aflatoxin B1 hemiacetal

A: As per the rules, only the first question can be answered. Organic reaction mechanism.

Q: Give the structure of the product from the reaction of propanal with 1M ethanol in dry acid . (…

A: Organic compounds are the compounds which are mainly composed C and H atoms. The branch of chemistry…

Q: In what major form would this diol-aldehyde exist? Н НО ОН НО. НО -ОН НО. B НО Он НО, "ОН D

A: The major form of given diol-aldehyde exist can be drawn as

Q: Draw structural formulas for both resonance structures of the enolate ion obeained by treating the…

A: Enolate ion :-  Enolate ion is obtained by the abstraction of alpha hydrogen atom from aldehydes or…

Q: Tertiary (3°) aromatic amines react with NaNO2 and HCl to afford products of electrophilic aromatic…

A: The electron withdrawing /electron releasing groups have important role in the activation and…

Q: A retrosynthetic analysis of 1 was undertaken suggesting a forward synthesis starting from compounds…

A: We have to synthesize organic compound 1 :

Q: The 1H NMR spectrum of N,N-dimethylformamide shows three singlets at 2.9, 3.0, and 8.0 ppm. Explain…

A: To explain this, 1) Draw the resonance structure of N,N-dimethylformamide. 2) Check whether rotation…

Q: How would you separate toluene (C6H5CH3), benzoic acid (C6H5CO2H), and aniline (C6H5NH2) by an…

A: The solvent extraction method should be adopted to separate the three components present in the…

Q: Explain why pyridine ( Kb=2.3x10-9) is a much stronger base than pyrrole (Kb=2.5x10-14)

A: Hey, since there are multiple questions posted, we will answer first question. If you want any…

Q: (ii) Give two reasons why only one equivalent of ethanol can be added to the carboxylic acid even…

A:

Q: Propose an explanation for the fact that the trifluoromethyl group is almost exclusively meta…

A:

Q: The reaction of a nitrile with an alcohol in the presence of a strong acid forms an N-substituted…

A:

Q: Explain the Nitration ?

A: Nitration is the addition of nitrogen to the the compound.

Q: Consider the following reaction schemes involving the reaction of an imine with an organolithium…

A: Non-bulky organolithiums like n-BuLi can undergo halogen exchange reaction as well as nucleophilic…

Q: How would the experiement change if we instead used racemic methylbenzylamine?

A: