2. Comparing the endogenous opioids in Table 1, identify the sequence that is the same among all the opioid peptides in the list This conserved sequence is most likely the segment that binds to the protein receptor Table 1. The most common endogenous opioid peptides produced in humans Рeptide Enkephalins Leu-enkephalin YGGFL Met-enkephalin YGGFM Metorphamide YGGFMRRV-NH2 Peptide E Peptide Sequence YGGFMRRVGRPEWWMDYQKRYGGFL Endorphins B-endorphin Y-endorphin a-endorphin YGGFMTSEKSQTPLVTLF KNAIIKNAYKKGE YGGFMTSEKSQTPLVTL YGGFMTSEKSQTPLVT Dynorphins Dynorphin A Dynorphin B Dynorphin1-8 YGGFLRRQ a-neoendorphin YGGFLRKYPK B-neoendorphin YGGFLRKYP YGGFLRRIRPKLKWDNQ YGGFLRRQFKWT

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Chapter9: Cell Communication
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Problem 8RQ: Endocrine signals are transmitted more slowly than paracrine signals because.___ the ligands are...
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2. Comparing the endogenous opioids in Table 1, identify the sequence that is the same among all
the opioid peptides in the list
This conserved sequence is most likely the segment that binds to the protein receptor
Transcribed Image Text:2. Comparing the endogenous opioids in Table 1, identify the sequence that is the same among all the opioid peptides in the list This conserved sequence is most likely the segment that binds to the protein receptor
Table 1. The most common endogenous opioid peptides produced in humans
Рeptide
Enkephalins
Leu-enkephalin YGGFL
Met-enkephalin YGGFM
Metorphamide YGGFMRRV-NH2
Peptide E
Peptide Sequence
YGGFMRRVGRPEWWMDYQKRYGGFL
Endorphins
B-endorphin
Y-endorphin
a-endorphin
YGGFMTSEKSQTPLVTLF KNAIIKNAYKKGE
YGGFMTSEKSQTPLVTL
YGGFMTSEKSQTPLVT
Dynorphins
Dynorphin A
Dynorphin B
Dynorphin1-8 YGGFLRRQ
a-neoendorphin YGGFLRKYPK
B-neoendorphin YGGFLRKYP
YGGFLRRIRPKLKWDNQ
YGGFLRRQFKWT
Transcribed Image Text:Table 1. The most common endogenous opioid peptides produced in humans Рeptide Enkephalins Leu-enkephalin YGGFL Met-enkephalin YGGFM Metorphamide YGGFMRRV-NH2 Peptide E Peptide Sequence YGGFMRRVGRPEWWMDYQKRYGGFL Endorphins B-endorphin Y-endorphin a-endorphin YGGFMTSEKSQTPLVTLF KNAIIKNAYKKGE YGGFMTSEKSQTPLVTL YGGFMTSEKSQTPLVT Dynorphins Dynorphin A Dynorphin B Dynorphin1-8 YGGFLRRQ a-neoendorphin YGGFLRKYPK B-neoendorphin YGGFLRKYP YGGFLRRIRPKLKWDNQ YGGFLRRQFKWT
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