2. The electron transfer potential of NADH and FADH2, relative to O2, drives oxidative phosphorylation and ATP synthesis. Oxidation of NADH occurs by the following reaction (1) : (1) 0.5 02 + NADH + H* H20 + NAD* The reaction above can be expressed in terms of the following half reactions: (2) 0.5 O2 + 2 H* + 2 e > H20 (3) NAD* + 2 H* + 2 e → NADH E. E, = -0.32 V = +0.82 V а. Calculate AE'0 and AGO for the oxidation of NADH (Reaction 1). b. What is AG'" for the synthesis of ATP from ADP? С. Using your results from Parts (a) and (b), explain how the electron transfer potential of NADH drives ATP synthesis.

2. The electron transfer potential of NADH and FADH2, relative to O2, drives oxidative phosphorylation and ATP synthesis. Oxidation of NADH occurs by the following reaction (1) : (1) 0.5 02 + NADH + H* H20 + NAD* The reaction above can be expressed in terms of the following half reactions: (2) 0.5 O2 + 2 H* + 2 e > H20 (3) NAD* + 2 H* + 2 e → NADH E. E, = -0.32 V = +0.82 V а. Calculate AE'0 and AGO for the oxidation of NADH (Reaction 1). b. What is AG'" for the synthesis of ATP from ADP? С. Using your results from Parts (a) and (b), explain how the electron transfer potential of NADH drives ATP synthesis.

Chemistry & Chemical Reactivity

10th Edition

ISBN:9781337399074

Author:John C. Kotz, Paul M. Treichel, John Townsend, David Treichel

Publisher:John C. Kotz, Paul M. Treichel, John Townsend, David Treichel

Chapter24: Biochemistry

Section: Chapter Questions

Problem 34GQ: The first step of the metabolic process known as glycolysis is the conversion of glucose to glucose-...

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