2',3'-Dideoxyinosine has been approved as an anti-HIV drug' Propose a mechanism by which it might block the growth of the HIV virus.
Q: Propose a unique target for a drug that would inhibit replication of retroviruses in humans
A: Viruses are obligate intracellular microorganisms that require a living cell for their growth and…
Q: Explain the mechanism by which some (+)ssRNA viruses are able to produce many (e.g. ~10) proteins…
A: In general viruses depend on host cells for: (1) energy, mainly in the form of nucleoside…
Q: Can you get reinfected with COVID-19 
A: COVID-19 Is an infectious disease that occurs by a virus called Coronavirus disease. It is a highly…
Q: HIV requires an enzyme called ______________ to convert its RNA genome to a DNA version. Why is this…
A: Human Immunodeficiency Virus attacks the body’s immune system threatening life with opportunistic…
Q: Besides being a general base, what's the other function of Asp in mechanism of HIV-1 aspartate…
A: HIV-1 Aspartate Protease is a retropepsin enzyme i.e., retroviral aspartyl protease enzyme. Besides…
Q: The anticlotting property of heparin is partly the result of the negative charges it carries. ( Q.)…
A: Introduction Heparin is the member of glycosaminoglycan family which contains sulfonate ions. It…
Q: Give an example of a nucleoside analogue that has been used successfully as an antiretroviral drug.…
A: Nucleoside analogue can be defined as a class of drugs ,which are mainly used to as antiviral agent…
Q: Draw and illustrate how latex agglutination works to bind to ASO and form agglutinates
A: Agglutination Test -- Tests are regarded as screening tests .There are many tests based on the…
Q: Clinical studies showed that zinc significantly shortens the duration of symptoms during rhinovirus.…
A: The common cold is caused by rhinovirus infections (rhinovirus implies "nose"). They can also induce…
Q: intercalating agent
A: Intercalation is the process in which there is the insertion of molecules between the planar bases…
Q: An antiviral drug that is a guianine analog would have an antiviral mode of action that: a) blocks…
A: Antimicrobial drugs are agents that inhibit the growth of microorganisms and kill them. They are…
Q: Describe: a.) the mechanism of action of PF-07321332, the active compound found in the antiviral…
A: Asked : PF-07321332 mechanism of action , viral target and product
Q: What properties make ribavirin an effective antiviral compound? Give an example of a virus and yay…
A: Infectious diseases are mainly caused by microorganisms such as bacteria, viruses, and fungi, etc.…
Q: xplain using 2-3 sentences the biological significance of the following peptides. Ceruloplasmin…
A: A peptide bond is generally a covalent chemical bond that conncedting two consecutive amino acid…
Q: Emtricitabine (2,3-dideoxy-5-fluoro-3'-thiacytidine, abbreviated as FTC) is a nucleoside analog that…
A: HIV: (human immunodeficiency virus) this is a virus that can attack our immune system. This virus…
Q: Q. "Pericarditis-myocarditis syndrome" is caused by which of the following cytotoxic agent?? A.…
A: Pericarditis- myocarditis syndrome:- Pericarditis is the inflammation of the outer fibro-serous…
Q: Explain how Stearic acid works again virus and kill virus? Explain the mechanism of action? Please…
A: Stearic acid prompted development constraint at absorption less than 50 μM, because higher…
Q: Because penicillin prevents peptidoglycan synthesis, it is more effective on cells.
A: In this question, effect of penicillin on the cell wall of different types of bacteria is to be…
Q: Biotransformation is an important concept in pharmacology, which amongst others, enables the…
A: Introduction:- A crucial stage in the cessation of action and removal of therapeutically useful…
Q: 00 Examine the structures below of several anti-viral drugs. Match the anti-viral drugs with the…
A: Inhibits the viral DNA polymerase of herpesvirus : Acyclovir Acyclovir triphosphate inhibits viral…
Q: Dr Janis toboggan has two patients who were admitted to her hospital with covid-19. And she gave…
A: The null hypothesis is the hypothesis which the researcher tries to disapprove or nullify whereas…
Q: One of the first and most important targets for drugs to fight infection with HIV (a retrovirus) is…
A: Human immunodeficiency virus (HIV) is a retrovirus that contains single-strand RNA genome. It…
Q: The structures of two antiviral drugs are shown below. Draw the structures of the natural compounds…
A: Antiviral drugs are considered as the class of medications, which is used to treat the infections…
Q: prevention of covid 19 should be done by everyone especially those with higher risks such as the…
A: COVID-19 is an infectious viral diseases caused by agent corona virus.
Q: how to cure from covid 19
A:
Q: what Mutations that cause penicillin resistance
A: Mutation is a sudden change in the structure of gene which results into a variant form that can be…
Q: Describe the mechanism through which oseltamivir (Tamiflu) inhibits influenza virus reproduction.
A: Oseltamivir (also known as TamifluR) is an antiviral neuraminidase inhibitor used to treat and…
Q: Tenofovir, an analog of adenosine monophosphate, is a nucleoside reverse transcriptase inhibitor…
A: Tenofovir, an analog of adenosine monophosphate, is a nucleoside reverse transcriptase inhibitor…
Q: a. Draw and label the different components of an antibody drug conjugate. Give examples of the…
A: Antibody Drug Conjugates are the class of drugs , which targets on cancerous cells. They are also…
Q: Explain the role of RNase H (a component of reverse transcriptase)during the synthesis of HIV DNA.
A:
Q: Many patients become resistant to HIV protease inhibitors with the passage of time, owing to…
A: HIV is the human immunodeficiency virus that causes immune deficiency syndrome in humans. They are…
Q: 2a.) Illustrate below the image you see when you observe the onion skin with the 4x and 40x…
A: Onion cells are smaller, thinner, and bricked together. The skin of the onion peel is a single cell…
Q: Replication of both strands of DNA in adenoviruses occurs ina continuous (leading) fashion. How can…
A: Adenovirus is the most common virus which causes common cold and flu. Adenovirus has a broad range…
Q: Illustrate how latex agglutination works to bind to ASO and form agglutinates
A: Answer: Introduction: The assessment of latex agglutination rest on what kind of sample is required.…
Q: The structures of two antiviral drugs are shown below. Draw the structures of the natural compounds
A:
Q: Imagine you are designing a new candidate molecule that can be used as an anti-viral drug to treat…
A: COVID is a deadly viral disease that has spread all over the world. Drug discovery and development…
Q: 1. Explain how acyclovir can be used to treated virus-infected cells.
A: The discovery of antiviral agents has been facilitated by advances in the fields of molecular…
Q: Nucleoside and nucleotide analogs are two closely related classes of anti-viral drugs that inhibit…
A: Nucleoside and nucleotide analogs are two classes of antiviral drugs. The difference between the two…
Q: Name a nucleoside analog. Explain how that nucleoside analog works. Which viruses are effectively…
A: Nucleoside analogues are nucleosides that contain a sugar and a nucleic acid counterpart. Nucleoside…
Q: why is testing known inhibitors of viral proteases from other viruses a logical first step in…
A: Protease in Corona virus cleaves the polyprotein in virus at 11 conserved sites. It is a kind of…
Q: Knowing that retroviruses operate on the principle of reversing thedirection of transcription from…
A: Retroviruses could do reverse transcription. That is, retroviruses could make DNA (deoxyribonucleic…
Q: Vaccines are an attractive prophylactic treatment against both viral and bacterial diseases. A…
A: Vaccines at molecular levels are antigens, a compound that binds antibodies. Since there is no live…
Q: Which of the following statement is false regarding the SARS-CoV-2 protease Mpro? a) Mpro catalyze…
A: The coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory…
Q: 17. The following is a true statement regarding hydroquinone as depigmenting agents.... A. has a…
A: Skin lightening agents are chemicals that lighten skin color. Hydroquinone, kojic acid, mono benzyl…
Q: Which of the following drugs inhibits protein synthesis through binding to ribosomal 30S subunit: a.…
A: Aminoglycide class of drugs works by irreversibly binding to the site on the bacterial 30S ribosome,…
Trending now
This is a popular solution!
Step by step
Solved in 2 steps
- Give an example of a nucleoside analogue that has been used successfully as an antiretroviral drug. How does it work thanksDescribe in some detail the mechanism of action of the penicillin drugs.Explain using 2-3 sentences the biological significance of the following peptides. Ceruloplasmin Oxytocin
- Below is the structure of an intercalating agent. By making reference to the structure of the compound, outline the essential structural features for the activity of intercalating drugs acting on DNA.Why is HIV protease a good target for anti-HIV therapy and drug discovery?Are the HIV-1 protease inhibitors transition state analogs? Why or why not?