Biology 2e
2nd Edition
ISBN: 9781947172517
Author: Matthew Douglas, Jung Choi, Mary Ann Clark
Publisher: OpenStax
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Textbook Question
Chapter 15, Problem 2VCQ
Figure 15.13 Errors in splicing are implicated in cancers and other human diseases. What kinds of mutations might lead to splicing errors? Think of different possible outcomes if splicing errors occur.
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Which of the following is an example of a post-translational modification?
Select an answer and submit. For keyboard navigation, use the up/down arrow keys to select an answer.
a
Splicing out introns!
b
Attachment of a poly-A tail!
c
Splicing out inteins!
d
Recruitment of 31 Mediator proteins that assemble around TATA.
Which of the following methods is utilized by eukaryotes to control their gene expression that is different from the type of control found in bacteria?
a) control of chromatic remodeling.
b) control of RNA splicing.
c) transcriptional control.
d) control of both RNA splicing and chromatin remodeling.
Alternative splicing
a. increases the number of proteins made from one gene
b. increases the number of primary transcripts made from one gene
c. increases the number of exons
d. increases the number of introns
Chapter 15 Solutions
Biology 2e
Ch. 15 - Figure 15.11 A scientist splices a eukaryotic...Ch. 15 - Figure 15.13 Errors in splicing are implicated in...Ch. 15 - Figure 15.16 Many antibiotics inhibit bacterial...Ch. 15 - The AUC and AUA codons in mRNA both specify...Ch. 15 - How many nucleotides are in 12 mRNA codons? 12 24...Ch. 15 - Which event contradicts the central dogma of...Ch. 15 - Which subunit of the E. coli polymerase confers...Ch. 15 - The -10 and -35 regions of prokaryotic promoters...Ch. 15 - Three different bacteria species have the...Ch. 15 - Which feature of promoters can be found in both...
Ch. 15 - What transcripts will be most affected by low...Ch. 15 - How do enhancers and promoters differ? Enhancers...Ch. 15 - Which pre-mRNA processing step is important for...Ch. 15 - What processing step enhances the stability of...Ch. 15 - A scientist identifies a pre-mRNA with the...Ch. 15 - The RNA components of ribosomes are synthesized in...Ch. 15 - In any given species, there are at least how many...Ch. 15 - A scientist introduces a mutation that makes the...Ch. 15 - Imagine if there were 200 commonly occurring amino...Ch. 15 - Discuss how degeneracy of the genetic code makes...Ch. 15 - A scientist sequencing itiRNA identifies the...Ch. 15 - If mRNA is complementary to the DNA template...Ch. 15 - In your own words, describe the difference between...Ch. 15 - A fragment of bacterial DNA reads: 3’...Ch. 15 - A scientist observes that a cell has an RNA...Ch. 15 - Chronic lymphocytic leukemia patients often harbor...Ch. 15 - Transcribe and translate the following DNA...Ch. 15 - Explain how single nucleotide changes can have...Ch. 15 - A normal mRNA that reads 5’ -...
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- IS. Alternative splicing has been estimated to occur in more than 95% of multi-exon genes. Which of the following is not an evolutionary advantage of alternative splicing? Alternative splicing increases diversity without increasing genome size Different gene isoforms can be expressed in different tissues Alternative splicing creates shorter mRNA transcripts Different gene isoforms can be expressed during different stages of development.arrow_forwardWhy is alternative splicing beneficial?arrow_forwardWhat is the purpose of alternative splicing a. Alternative spiicing allows a protein to be included by multiple genes b. Alternative spicing allows for mutations to accumulate that won't affect the expression of a gene c. Alternative splicing allows for multiple mRNAs to be produced to ensure that the single proteins the gene and codes will be translated. d.arrow_forward
- The asterisk (*) in the diagram below indicates a single base mutation in the 5' splice site of the second intron of a eukaryotic gene. Due to this mutation, the second intron is now not ‘spliced out’ during the splicing process. What are the most likely consequences of this mutation with respect to the size of the pre-mRNA and the size of the mature mRNA? a. The pre-mRNA will be longer and the mature mRNA will be longer. b. The pre-mRNA will be longer and the size of the mature mRNA will not be affected c. The size of the pre-mRNA will not be affected and the mature mRNA will be longer d. The size of the pre-mRNA will not be affected and the size of the mature mRNA will not be affectedarrow_forwardHow would each of the following types of mutations affect proteinfunction or the amount of functional protein that is expressed froma gene?A. Nonsense mutationB. Missense mutationC. Up promoter mutationD. Mutation that affects splicingarrow_forwardThe pre-mRNA transcript and protein made by several mutant genes were examined. The results are given below. Determine where in the gene a likely mutation lies: the promoter region, exon, intron, cap on mRNA, or ribosome binding site. a. normal-length transcript, normal-length nonfunctional protein b. normal-length transcript, no protein made c. normal-length transcript, normal-length mRNA, short nonfunctional protein d. normal-length transcript, longer mRNA, shorter nonfunctional protein e. transcript never madearrow_forward
- Different forms of a protein are produced in the liver and in the brain by alternate splicing of its mRNA. How would a researcher clone the gene encoding that protein to study the form that was produced in the liver?arrow_forwardWhich of the following is likely associated with the mRNA processing step of alternative splicing? 1. A gene is discovered to encode for two different proteins one protein has 46 amino acids and the other protein has 86 amino acid 2. A gene has 7 exons. one processed mRNA transcript from this gene contains exons 3, 4, 6 and 7. a second process mRNA transcript from this gene contains exons 2, 3, 5, and 7 3. The open reading frame of a gene contains 90 nucleotides but the translated polypeptide contains only 29 amino acids 4. Complexity of the transcrptome ( # of different mRNA molecules) increasesarrow_forwardThe animated figure below shows formation of the lariat during mRNA splicing. Consider this figure as you answer the following question.arrow_forward
- Which of the following makes alternative RNA splicing possible? Group of answer choices A. Parts of a gene can function as exons or introns B. DNA methylation C. Parts of a gene can be either transcribed or not D. Histone Acetylation E. Parts of a gene can bind to RNA polymerase or notarrow_forwardHow is it possible that alternative splicing can effectively increase the number of genes in the genome?arrow_forwardExplain how each of the following processes complicates the concept of colinearity. Q. Alternative splicingarrow_forward
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