7. Describe the mutation that causes sickle cell anemia. a. What is the change that occurs in DNA? b. What is the amino acid change that happen? Is it a conservative (similar amino acid) change or not? C. What is the change in tertiary structure? d. What is the change in quaternary structure? e. How is it possible that such a (small) change causes such an extreme effect?

7. Describe the mutation that causes sickle cell anemia. a. What is the change that occurs in DNA? b. What is the amino acid change that happen? Is it a conservative (similar amino acid) change or not? C. What is the change in tertiary structure? d. What is the change in quaternary structure? e. How is it possible that such a (small) change causes such an extreme effect?

Biology (MindTap Course List)

11th Edition

ISBN:9781337392938

Author:Eldra Solomon, Charles Martin, Diana W. Martin, Linda R. Berg

Publisher:Eldra Solomon, Charles Martin, Diana W. Martin, Linda R. Berg

Chapter12: Dna: The Carrier Of Genetic Information

Section: Chapter Questions

Problem 1TYU: When Griffith injected mice with a combination of live rough-strain and heat-killed smooth-strain...

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1. Below is the base sequence of protein for normal hemoglobin and the base sequence for the sickle cell hemoglobin:Normal: GGG CTT CTT TTTSickle: GGG CAT CTT TTTa. Transcribe and translate the normal and sickle cell DNA. b. Identify this as a point or frameshift mutation. Explain. c. If the base sequence read GGG CTT CTT AAA instead, would this result in sickle cell hemoglobin? Explain.
5. If 18% of the nucleotide bases in a DNA molecule are Guanine (G) A. What % of the bases are cytosine (A)? B. What % of the bases are adenine (A) and thymine (T) combined? C. What % of the bases are thymine alone?
1. a) What does DNA stand for? b)What is the name of the DNA structure?
6. The basic functional and structural unit of heredity is A. Gene B. Nucleotide C. Phosphate D. Nitrogen
4. If a DNA triplet is CGA A. What is the mRNA codon? B. What is the tRNA anticondon? C. What amino acid does the mRNA code for? 5. If 18% of the nucleotide bases in a DNA molecule are Guanine (G) A. What % of the bases are cytosine (A)? B. What % of the bases are adenine (A) and thymine (T) combined? C. What % of the bases are thymine alone?
5. If 30% of the bases in human DNA are A, (a) whatpercentage are C? (b) What percentage are T?(c) What percentage are G?
When Griffith injected mice with a combination of live rough-strain and heat-killed smooth-strain pneumococci, he discovered that (a) the mice were unharmed (b) the dead mice contained living rough-strain bacteria (c) the dead mice contained living smooth-strain bacteria (d) DNA had been transferred from the smooth-strain bacteria to the mice (e) DNA had been transferred from the rough-strain bacteria to the smooth-strain bacteria
The two complementary strands of the DNA double helix are held to each other by (a) ionic bonds between deoxyribose molecules (b) ionic bonds between phosphate groups (c) covalent bonds between nucleotide bases (d) covalent bonds between deoxyribose molecules (e) hydrogen bonds between nucleotide bases
The experiments in which Meselson and Stahl grew bacteria in heavy nitrogen conclusively demonstrated that DNA (a) is a double helix (b) replicates semiconservatively (c) consists of repeating nucleotide subunits (d) has complementary base pairing (e) is always synthesized in the 5 3 direction
7.What type of mutation occurred in the example above (question #6)? Did the polypeptide change? Why or why not?
1. Explain the central dogma - how DNA, RNA, and proteins are related.
5)Which type of nucleic acid would have the sequence "ACCGAUUG"? a)DNA b)mRNA c)Another type of nucleic acid d)More information is needed