A family has an X-linked dominant form of congenital generalizedhypertrichosis (excessive hairiness). Although the allele is dominant,males are more severely affected than females. Moreover, the womenin the family often have asymmetrical, hairy patches on their bodies.How does X chromosome inactivation explain this observation?

Q: Let’s suppose that two different X-linked genes exist in mice,designated with the letters N and L.…

A: The distance between the two genes N and L  can be surveyed by making crosses and by examining the…

Q: In this pedigree, affected individuals have a disease causing the inability to walk forward, called…

A: Genes are the hereditary unit of an organism. The genes have DNA (deoxyribonucleic acid) which code…

Q: The ABO blood type locus has been mapped on chromosome 9. A father who has type AB blood and a…

A: A cross is made between a male and a female the male having an 'AB 'blood group and the mother…

Q: Cystic fibrosis is a genetic disorder that damages the tissues of the lungs. A – normal a -…

A: Sir Gregor Mendel was a priest and a teacher who did the famous hybridization experiment on garden…

Q: Xg is an antigen found on red blood cells. This antigen is caused by an Xlinked allele (Xa) that is…

A: X linked alleles are those alleles which are present on the X chromosome. They have distinctive…

Q: What sex ratio would you expect among the offspring of a cross between a normal mape mouse and a…

A: Sex ratio is defined as the ratio of males and females in the population. Generally in sexually…

Q: Xg is an antigen found on red blood cells. This antigen is caused by an Xlinked allele (Xa) that is…

A: The X alleles are present in the X chromosome, which is a sex-chromosome. The number of X…

Q: The ABO blood type locus has been mapped on chromosome 9. A father who has type AB blood and a…

A: A cross is made between a father and a mother the father have an 'AB' blood group and the mother…

Q: The prenatal cells have" Aacc" type alleles, which gamete is not possible?

A: There are majorly three laws proposed by Mendel, which include law is Segregation that describes the…

Q: Why is the development of individuals with Klinefelter's and Turner's syndromes relatively normal,…

A: This syndrome occur due to presence of an additional copy of X chromosomes resulting into karyotype…

Q: A person with Down syndrome has three copies of chromosome 21. Which of the following words should…

A: Triploid is used for defining the genomic content of an organism so, here the genomic content is 3n.…

Q: Butterflies have an X-Y sex-determination system that is different from that of flies or humans.…

A: -The butterfly shown has a completely unique pattern of colors because o a special trait- it has two…

Q: A purebred, red-eyed female fruit fly is mated with a white-eyed, male fruit fly. White eyes are…

A: All mammalian organisms exhibit sexual dimorphism. It means that there is the presence of a male and…

Q: In humans, hemophilia is an X-linked recessive gene and will only be expressed in females if  they…

A: Hemophilia is a X linked recessive disorder so which is inherited in homozygous condition. In rare…

Q: Why is an X chromosome needed for survival?

A: The sex chromosomes or allosomes are X and Y chromosomes which determine the biological sex of an…

Q: Human sex-linked disorders in which male children are affected and female children are carriers are…

A: Sex-linked or X-linked disorders mainly affect the males. Some sex-linked disorders are colour…

Q: . Researchers discovered recently that the sole functionof the SRY protein is to activate an…

A: There are various genetic disorders that develop due to anomalies in sex chromosomes. They normally…

Q: For the following chromosome complements, what is the phenotypic sex of a person who has Q. XX with…

A: The sex-determining region Y (SRY) is located on the short branch of the Y chromosome, which…

Q: How many Barr bodies in a person with genotype XXXXX? How is the structure of a Barr body different…

A: The mammalian males contain XY chromosome and females contain XX chromosome. So, the number of…

Q: Xg is an antigen found on red blood cells. This antigen is caused by an Xlinked allele (Xa) that is…

A: The offspring (diploid) receives one set of chromosomes from both the parents. The one set received…

Q: Explain why a person with Klinefelter Syndrome (XXY) still exhibits abnormal phenotypes despite the…

A: The human sex is determined at the time of fertilization in the fallopian tube of the female…

Q: Explain the difference between X-linked recessive traits and X-linked dominant traits. What are the…

A: Some diseases are inherited genetically. These diseases are either autosomal or sex-linked. Genes of…

Q: . A woman with Turner syndrome is found to be colorblind (an X-linked recessive phenotype). Both her…

A: Turner syndrome is a chromosomal disorder that impairs women's development. Half of the sex…

Q: What kind of chromosomal mutations is/are produced by unequal crossing over?

A: Mutation refers to both the process of altering a gene or chromosome and the outcome of that…

Q: What is the phenotype of a person who has XXXY sex chromosomes? a. Klinefelter syndromeb. Turner…

A: Genetics is the branch of biology that deals with the study of genes, their variation, and heredity…

Q: Which of the following karyotypic sex chromosome abnormalities result(s) in a male phenotype?…

A: Genetic diseases are caused by mutations in genes.

Q: Duchenne muscular dystrophy is a recessive disorder caused by a rare,loss-of-function allele that is…

A: Duchenne muscular dystrophy (DMD) is a quickly progressive type of muscular dystrophy that happens…

Q: Why does a single X chromosome cause infertility and other abnormalities in Turner Syndrome…

A: Turner syndrome (TS) is a genetic disorder that mostly affects females. The clinical features of…

Q: Which of the following statements is false?

A: Aneuploidy is the addition or deletion of one or more chromosomes.  Trisomy is the addition of one…

Q: Describe when X-chromosome inactivation occurs and how thisleads to phenotypic results at the…

A: Chromosomes are the carrier of genetic material deoxyribonucleic acid (DNA). They are coiled in…

Q: A homozygous gray female is crossed with a yellow male. The F1 are intercrossed to produce the F2.…

A: It is given that a homozygous gray female is crossed with the yellow male. The yellow color due to…

Q: Chorionic villus sampling is a procedure to determine if there are any abnormalities in chromosome…

A: Chorionic villus sampling is also used for the same purpose. Chorion is basically a membrane that…

Q: EXAMPLE Ah nas a rare X-linked dominant condition called amelogenesis Imperfecta, whicn results in…

A: Amelogenesis imperfecta is due to the malfunction of the proteins in the enamel as a result of…

Q: A normal female Drosophila produces abnormal eggs that contain all (a complete diploid set) of her…

A: Although the two mammals and fruit flies produce XX females and XY male, their chromosomes…

Q: Researchers discovered recently that the sole functionof the SRY protein is to activate an autosomal…

A: Sex-determining region of Y (SRY) is responsible for maleness in males. Mutation in the SRY region…

Q: On average, what will be the proportion of X-linked genes in the second individual that are the same…

A: Genetics is the study of genes, their interactions, and the effect of environment on genes. Broadly…

Q: A human child is born with hemophilia (a condition in which the blood does not clot).  Neither…

A: Given: A human child is born with hemophilia (a condition in which the blood does not clot). Neither…

Q: Some individuals grow ear hair later in life, the gene for this trait is beleived to be carried on…

A: The phenotypic expression is the ultimate product of a gene. All of our phenotypic characteristics…

Q: Men have XY​ (or YX) chromosomes and women have XX chromosomes.​ X-linked recessive genetic…

A: The trait is X linked recessive in nature.  The X chromosome encodes normal phenotype. It is…

Q: Can a female parent pass a X-Linked Trait to a XY offspring?

A: Inheritance is the process in which genetic information is passed from one generation to another.…

Q: Incontinentia pigmenti, a rare, X-linked dominant disorder inhumans, is characterized by swirls of…

A: Incontinentia pigmenti is a genetic disorder that damages the skin and is more frequent in females…

Q: In 1952, an article in the British Medical Journalreported interesting differences in the behavior…

A: In the given data, hemophilia is an X-linked recessive disorder. There are interesting differences…

Q: Why do individuals with an excessive number of sex chromosomes often show minimum phenotypes?

A: Introduction :- The X and Y chromosomes are found in humans and most other mammals. Males have both…

Q: In 1916, Dorothy Osborn suggested that pattern baldness is a sex-influenced trait that is dominant…

A: Pattern baldness is a sex-influenced trait that is dominant in males and recessive in females. The…

Q: Xg is an antigen found on red blood cells. This antigen is caused by an Xlinked allele (Xa) that is…

A: There are two types of chromosomes present in human: autosomes and sex chromosomes. The transmission…

Q: In elegans, lon-2 and unc-2 are recessive mutations that are 8 map units apart on the X chromosome.…

A: A map unit is defined as the distance between two linked gene pairs where 1% of the products of…

Mitochondrial Mutations

A mitochondrion is a cellular organelle that serves as the site for cellular respiration and energy production (ATP or Adenosine Triphosphate). It is a double-membrane-bound organelle and is only present in eukaryotic cells.