a. 2,2,2-Trifluoroethanol vs. ethanol F3C НО. pKa = 12.5 16.0 b. Thiophenol vs. phenol SH HO pKa = 6.6 10.0 c. Protonated methanol vs. protonated methylamine COH2 'HN pka = -2.5 10.6

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NMR Spectroscopy

NMR stands for Nuclear Magnetic Resonance in which the study of different molecules is done based on the interaction of radiofrequency electromagnetic radiations with the nuclei of molecules placed in a strong magnetic field. A precise study of spectra of visible light and all bands of electromagnetic radiation is called spectroscopy.