a. The eyeless gene is required for eye formation in Drosophila. It encodes a homeodomain. What would you predict about the biochemical function of the Eyeless protein?b. Where would you predict that the eyeless gene is expressed in development? How would you test your prediction? c. The Small eye and Aniridia genes of mice and humans, respectively, encode proteins with very strong sequence similarity to the fly Eyeless protein, and they are named for their effects on eye development. Devise one test to examine whether the mouse and human genes are functionally equivalent to the fly eyeless gene.

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
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Chapter1: The Human Body: An Orientation
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a. The eyeless gene is required for eye formation in
Drosophila. It encodes a homeodomain. What would you
predict about the biochemical function of the Eyeless
protein?
b. Where would you predict that the eyeless gene is
expressed in development? How would you test your
prediction?
c. The Small eye and Aniridia genes of mice and humans,
respectively, encode proteins with very strong sequence
similarity to the fly Eyeless protein, and they are named
for their effects on eye development. Devise one test to
examine whether the mouse and human genes are
functionally equivalent to the fly eyeless gene.

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