Although both hexokinase and phosphofructokinase catalyze irreversible steps in glycolysis and the hexokinase-catalyzed step is first, phosphofructokinase is nonetheless the pacemaker of glycolysis. What does this information tell you about the fate of the glucose 6- phosphate formed by hexokinase?

Although both hexokinase and phosphofructokinase catalyze irreversible steps in glycolysis and the hexokinase-catalyzed step is first, phosphofructokinase is nonetheless the pacemaker of glycolysis. What does this information tell you about the fate of the glucose 6- phosphate formed by hexokinase?

Concepts of Biology

1st Edition

ISBN:9781938168116

Author:Samantha Fowler, Rebecca Roush, James Wise

Publisher:Samantha Fowler, Rebecca Roush, James Wise

Chapter4: How Cells Obtain Energy

Section: Chapter Questions

Problem 17CTQ: Both prokaryotic and eukaryotic organisms carry out some form of glycolysis. How does ha fact...

See similar textbooks

Related questions

Q: If glutamate were labeled with C-14 at the delta-carbon and added via transamination to the citric…

A: Citric Acid Cycle: is the cyclic metabolic pathway for the oxidation of various intermediates…

Q: The glucose/glucose-6-phosphate substrate cycle involves distinct reactions of glycolysis and…

A: Hello. Since your question has multiple parts, we will solve the first question for you. If you want…

Q: How does control of the glucose6-phosphatase reaction differ from that of the fructose-1,6-…

A: Gluconeogenesis is the formation of glucose. It resembles reversal of glycolysis. Three steps of…

Q: What effect will an increase in oxaloacetate in mitochondria have on fatty acid biosynthesis? (b)…

A: Fatty acid biosynthesis occurs through condensation of C2 units, the reverse of fatty acid…

Q: For each of the following conditions, state whether this condition would be occurring during…

A: As per the honor code, we answer only three subparts at a time. Therefore we are answering the first…

Q: Which of the following products of the non-oxidative stage of PPP is an intermediate of the…

A: The hexose monophosphate shunt, also known as the pentose phosphate pathway, is a shunt from…

Q: In the citric acid cycle, the coenzyme NAD is required for which of the following reactions (Choose…

A: NAD or Nicotinamide adenine dinucleotide is a type of coenzyme that plays a crucial role in cellular…

Q: How does control of the glucose-6-phosphatase reaction differ from that of the…

A: Glucose-6-phosphatase is an enzyme that catalyzes the hydrolysis of glucose-6-phosphate into glucose…

Q: Glucose is converted to pyruvate in glycolysis, yielding a netsynthesis of 2 ATP. In certain cells…

A: Gluconeogenesis is the process of synthesis of glucose from non-carbohydrate sources such as amino…

Q: How does the hydrolysis of fructose-1,6- bisphosphate bring about the reversal of one of the…

A: Glycolysis is a metabolic process that breaks down glucose to form pyruvate and two adenosine…

Q: Which enzyme catalyzes a freely reversible reaction? Pyruvate dehydrogenase Aconitase…

A: The citric acid cycle enzymes are membrane proteins present in the matrix of the mitochondria except…

Q: Why, do you suppose, the coenzyme for the reaction in the citric acid cycle that is catalyzed by…

A: Succinate dehydrogenase is an enzyme complex found in inner mitochondrial membrane and participates…

Q: How many turns of the citric acid cycle are implicated in accounting for the net oxidation of one…

A: The citric acid cycle, which is found to be a part of cellular respiration, takes place inside the…

Q: Although most enzymes are quite specific, they can catalyze side reactions with compounds that are…

A: NAD NAD is Nicotinamide adenine dinucleotide NAD is the coenzyme form of Vitamin B5 (Niacin). It…

Q: Hexokinase catalyzes the first step of glycolysis, in which glucose is phosphorylated to form…

A: Glycolysis is a process in which glucose is converted into pyruvate.

Q: The glycerol derived from lipolysis of triacylglycerols is converted into glyceraldehyde…

A: Glycolysis is considered as a process in which glucose is converted into pyruvate molecule.

Q: What is the effect of an increase in the levels of glyceraldehyde-3-phosphate (G3P) on glycolysis.…

A: Amid the oxidation of glyceraldehyde 3-phosphate to 1,3-diphosphoglycerate, which is the as it were…

Q: aking into consideration glycolysis, the pyruvate dehydrogenase complex and the citric acid cycle,…

Q: How many ATPs would result from the reaction involving the alpha-ketoacid dehydrogenase complex…

A: 1 mole of a substance consists of 6.02 x 1023 molecules.1 mole of glucose would consist of 6.02 x…

Q: The Km and kcat for fumarase with fumarate as a substrate are 5 × 10−6 M and 8 × 102 s−1,…

A: The citric acid cycle is the metabolic pathway, during which the oxaloacetate is formed from the…

Q: The pyruvate →lactate reaction in animals is reversible, but the pyruvate → ethanol fermentation in…

A: Anaerobic respiration or fermentation is conversion of glucose into energy which is very less as…

Q: The conversion of 1 mol of fructose 1,6-bisphosphate to 2 mol of pyruvate by the glycolytic pathway…

A: Glycolysis involves converting glucose into pyruvate in order to generate ATP, the energy currency…

Q: List the three different routes to catabolize glucose to Why is it necessary to start by spending…

A: Glucose catabolism - The breakdown of glucose to produce energy is called glucose catabolism. Only…

Q: What are the two most common inhibitors of stepsof the citric acid cycle and the reaction catalyzed…

A: The citric acid cycle that takes place in the mitochondrial matrix is the second step of aerobic…

Q: How many moles of ATP are synthesized by adding stearate to TCA through B-oxidation? Why is that?…

A: From the Beta oxidation process: The P/O ratios, which give the number of ATP produced per molecule,…

Q: What glycolytic intermediate does glycogenolysis produce? Explain in brief..

A: Glycolysis is a metabolic pathway in which glucose is converted to pyruvate. The principal sugars…

Q: Which of the following products of the non-oxidative stage of PPP is an intermediate in the…

A: PPP : Pentose phosphate pathway The non-oxidative phase of PPP links the glycolysis to the pentose…

Q: DEFINE THE FOLLOWING TERMS: a) Gluconeogenesis b) Glycolysis c) Citric Acid…

A: Metabolic pathways play important role in the maintenance of life. Complex molecules are broken down…

Q: The malaria parasite Plasmodium falciparum does not carry out oxidative phosphorylation and…

A: Krebs cycle is the metabolic pathway that oxidizes acetyl CoA into oxaloacetate in series of…

Q: Which one of the following regarding the chemistry of glycolysis & gluconeogenesis is FALSE?

A: Glycolysis is breakdown of glucose while gluconeogenesis is formation of glucose. Gluconeogenesis…

Q: What are the similarities and differences between the reactions catalyzed by pyruvate dehydrogenase…

A: Introduction Respiration is a metabolic process involving the oxidation of organic compounds to form…

Q: The oxidation of glyceraldehyde 3-phosphate to 1,3-bisphosphoglycerate, catalyzed by glyceraldehyde…

A: Glycolysis is the process of oxidation of glucose molecule where it occurs in two phases:…

Q: Which of the following enzymes is found in gluconeogenesis but not in glycolysis? a. phosphohexose…

A: Other metabolites can be transformed into glucose through gluconeogenesis. Aside from leucine and…

Q: Which of the following events does not occur during Krebs Cycle? Citrate synthase catalyzers the…

A: Statements related to Krebs cycle events are given.

Q: Other than oxidative phosphorylation, what other metabolic pathway does "Complex 2" participate in?…

A: Oxidative phosphorylation is the process by which ATP is synthesized as a result of electron…

Q: A rate limiting enzyme for glycolysis is, while a rate limiting enzyme for gluconeogenesis is . O…

A: Glycolysis is a metabolic pathway. In this pathway, the glucose is broken down and energy in the…

Q: Why is it advantageous for citrate, the product of Reaction 1 of the citric acid cycle, to inhibit…

A: Glycolysis is the process by which one molecule of glucose is converted into two molecules of…

Q: what is one physiological consequence that might occur if gluconeogenesis was the exact opposite of…

A: Gluconeogenesis is a process by which glucose molecules are produced from non-carbohydrate…

Q: How many steps in gluconeogenesis are not the exact reversal of the steps in glycolysis? What kind…

A: Glycolysis is the process in which degradation of glucose occurs while gluconeogenesis is the…

Q: In the first stage of glycolysis, fructose-1,6-bisphosphate iscleaved to form…

A: All cells require energy (ATP) to carry out various cellular processes, such as active transport,…

Q: Why is there such a large range of ∆G for the second step of glycolysis?

A: Glycolysis is the sequence of reactions that are used to break down glucose into two three-carbon…

Q: .What would happen in the Krebs cycle with the loss of activity of phosphoglycerate kinase? What…

A: Hi! Since you have posted multiple questions and have not mentioned which question to answer, we…

Q: Each of the following enzymes are similar in that they are all regulation points for the…

A: Enzymes are chemical substances that function in several biochemical reactions and help in the…

Q: Which steps of glycolysis are irreversible? What bearing does this observation have on the reactions…

A: Glycolysis is a catabolic process that involves the breakdown of glucose into pyruvate whereas…

Q: catalyzed by TPI, as illustrated at the beginning of Question #3. Explain why this step is suitable…

A: Glycolysis is a biochemical process that consists of ten biochemical reactions to convert glucose…

Q: What is the ATP yield from lactate if lactate is fully catabolized aerobically? (Note: This process…

A: Pyruvate is converted to pyruvate by lactate dehydrogenase enzyme (LDH) under anaerobic conditions.…

Q: Relate the names and function and functions of the following glycolytic enzymes to steps in the…

A: Glycolysis is the metabolic pathway that converts glucose into pyruvate. The free energy released in…

Q: Step 4 of the pentose phosphate pathway converts ribulose-5-phosphate to ribose-5-phosphate. Which…

A: There are two types of sugars- One containing the ketone as functional group. They are known are…

Concept explainers

Metabolic pathways

Metabolism is defined as the group of life-supporting, enzyme-mediated chemical reactions in organisms. A metabolic pathway is a set of these chemical reactions that involve anabolism (synthesis of complex biomolecules) and catabolism (breakdown of biomolecules into small molecules) that occur inside a cell. Metabolites are the reacting substances, products, and intermediate substances of an enzymatic process that are altered by a series of chemical events catalyzed by enzymes.

Question

Expert Solution

This question has been solved!

Explore an expertly crafted, step-by-step solution for a thorough understanding of key concepts.

This is a popular solution!

SEE SOLUTION Check out a sample Q&A here

Step 1

VIEW

Step 2

VIEW

Trending now

This is a popular solution!

Step by step

Solved in 2 steps

SEE SOLUTION Check out a sample Q&A here

Knowledge Booster

Learn more about

Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biochemistry and related others by exploring similar questions and additional content below.

Similar questions

Both prokaryotic and eukaryotic organisms carry out some form of glycolysis. How does ha fact support or not support the assertion that glycolysis is one of the oldest metabolic pathways?
Based on your knowledge of the structure of NAD+ and an assumption that coenzyme dissociation is the rate limiting step of the alcohol dehydrogenase mechanism, hypothesize why a N249W mutation at the coenzyme binding site would increase the rate of catalysis.
Why is it advantageous for citrate, the product of Reaction 1 of the citric acid cycle, to inhibit phosphofructokinase, which catalyzes the third reaction of glycolysis?
What if the phosphate group for the glycolysis reaction with enzyme glyceraldehyde 3-phosphate dehydrogenase was from ATP instead of Pi? What would the complete, balanced, net rxn of glycoslysisequation be and how does this impact the overall glycolysis rxn?
Xylulose-5-phosphate is an intermediate in the pentose phosphate pathway (see Figure). As xylulose-5-phosphate levels rise in response to excess glucose shunting through the pentose phosphate pathway, does flux through glycolysis increase or decrease?
If glutamate were labeled with C-14 at the delta-carbon and added via transamination to the citric acid cycle to produce alpha-ketoglutarate, how long would it take for the compounds containing C-14 to be reduced by 25% (assume 10 seconds per turn of the cycle)?
The conversion of 1 mol of fructose 1,6-bisphosphate to 2 mol of pyruvate by the glycolytic pathway results in what type of net formation?
Why is the isomerization of glucose-6-phosphate (G6P) to fructose-6-phosphate (F6P) an important step in glycolysis? How is the isomerization of F6P back into G6P prevented?
How many steps in gluconeogenesis are not the exact reversal of the steps in glycolysis? What kind of conversion of substrate to product does each involve? What is the common theme in each of these reactions?
The glycerol derived from lipolysis of triacylglycerols is converted into glyceraldehyde 3-phosphate, which then enters into step 6 of the glycolysis pathway. What further transformations are necessary to convert glyceraldehyde 3-phosphate into pyruvate?
The conversion of glyceraldehyde-3-phosphate to 1,3-bisphosphoglycerate is the only oxidative reaction of glycolysis. True or false?
Hexokinase catalyzes the first step of glycolysis, in which glucose is phosphorylated to form glucose‑6‑phosphate. Give two reasons why a Mg2+ cation is required to facilitate this reaction.