B1. Complete the Kreb's Cycle Acetyl CoA Citric Acid Malate dehydrogenase NADH NAD Isocitrate NAD Isocitrate Fumarase dehydrogenase NADH Fumarate
Q: Consider the Kreb's Cycle below. Fill in the blanks using the pool of answers below. Acetyl-SCOA…
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Q: Acetyl CoA 1. Citric Acid 9. Malate dehydrogenase NADH NAD Isocitrate 8. NAD 1- Isocitrate Fumarase…
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Q: mechanism of Fatty acid oxidation
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Q: Name the vitamin to which each of these coenzymes is related.(a) FAD (b) Coenzyme A(c) NAD+
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A: Fasting and starvation both are different terms.
Q: Define beta oxidation.
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Q: i) Acetyl-CoA ii) FADH2 and NADH
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Q: B1. Complete the Kreb's Cycle Acetyl CoA Citric Acid Malate dehydrogenase NADH NAD Isocitrate NAD…
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A: Pyruvate dehydrogenase reaction is a reaction in which pyruvate is converted into acetyl-CoA.
Q: Define the following terms:a. b-oxidationb. carnitinec. ketogenesisd. ketone bodiese. ketosis
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Q: is slowed down due to oxaloacetate being diverted to for citric acid cycle, gluconeogenesis O citric…
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- Understanding the Mechanism of Hemolytic Anemia Genetic defects in glycolytic enzymes can have serious consequences for humans For example, defects in the gene for pyruvate kinase can result in a condition known as hemolytic anemia. Consult a reference to learn about hemolytic anemia, and discuss why such genetic defects lead to this condition.GTP or ATP is produced during the conversion of isocitrate into ketoglutarate succinyl CoA into succinate fumarate into malate malate into oxaloacetateComplete oxidation of a 16-carbon fatty acid can yield 129 molecules of ATP Study Figure 19.2 and determine how many ATP molecules would be generated if a 16-carbon fatly acid were metabolized solely by the TCA cycle, in the form of S acetyl-CoA molecules.
- Radiolabeling with 14C-Glutamate Describe the labeling pattern that would result from the introduction into the TCA cycle of glutamate labeled at Cy with 14C.Complete the table below. Consider docosanoic acid (C21H43CO2H) Questions Show complete solutions Answers a. How many acetyl CoA molecules are formed by complete B-oxidation? b. How many cycles of B-oxidation are needed for complete oxidation? c. How many molecules of ATP are formed from the complete catabolism of this fatty acid?Discuss the metabolic control for HMG CoA reductase synthesis and activity
- Indicate what will happen ( increase, decrease or no effect) tothe activity of the enzyme or rate of the metabolic pathway in the given conditions a. release of glucagon in the blood to the activity of carnitine acyl transferase 1 b. high malonyl CoA to the activity of carnitine acyl transferase I C. Epinephrine to the activity og glycogen synthase d. high citrate to the activity of acetyl CoA carboxylase e. high acetyl CoA to ketogenesisGive answer of 1,2,3, MCQ's 1. Which of the following statements about delto-ALA (amino amino ievulinate Synthases are FALSE? A It catalyzes the rate limiting step in the pathway of heme synthesis B. It is allosterically activated by heme C. It synthesizes delta-ALA from glycine and acetyl-CoA D. It has a decreased activity in case of vitamin 87 deficiency E. Heme influences the concentration of delta-ALA synthase in the red blood cell precursor. 2. Select the correct statements about heme degradation: A. It involves the removal of Fe2+ from heme molecule with the generation of protoporphyrin B. During heme degradation, the protoporphyrin ring is opened and CO is released C Bilirubin is conjugated with UDP glucuronic in the spleen D. The conjugated bilirubin is transported in plasma by albumin E. The stercobilin that arises by the oxidation of urobilinogen confers the characteristic color of the feces 3. Which of the following represent possible consequences of an intense hemolysis…Pharmaceuticals in a class called the statins inhibit theenzyme HMG-CoA reductase. What is the primary effect ofthis drug on patients?
- Consider the fatty acids: (a) Arachidic acid (C20H40O2); molar mass = 312.5 g/mol) (b) Palmitoleic acid(C16H30O2); molar mass = 256.4 g/mol). i. How many cycles of β -oxidation are needed for complete oxidation?ii. How many molecules of acetyl CoA are formed from its complete catabolism?iii. Calculate the number of molecules (moles) of ATP formed (net) by the completecatabolism of each fatty acid (show your calculation).iv. Calculate number of moles of ATP formed per gram of each fatty acid metabolized.Consider docosanoic acid C12H43CO2H a. Label the alpha and beta Carbons. Show the beta-oxidation in an EXPANDED structure. b. Draw each acyl CoA derived from this fatty acid. c. How many acetyl Co A molecules are formed by complete beta-oxidation? d. How many cycles of beta-oxidation are needed for complete oxidation? e. How many molecules of ATP are formed from the complete catabolism of this fatty acid? Show the complete computation. f. How many moles of ATP per gram of fatty acid is formed from the complete catabolism of the given fatty acid? g. What is the molar mass of the given fatty acid? Solution: Show here the complete computations, [from a to e]In the context of fatty acid oxidation to acetyl CoA, indicate whether each of the following substances is involved in (1) fatty acid activation, (2) fatty acid trans-port, or (3) b-oxidation pathway. More than one choice may be correct in a given situation. a. AMp b. FAD c. Acyl CoA d. H2O